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All HBS Web
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- Faculty Publications (139)
- 2021
- Working Paper
SSRIs and Non-SSRIs (through 1999): Case Histories of Significant Medical Advances
By: Amar Bhidé, Srikant M. Datar and Katherine Stebbins
Our case history describes the development of Prozac, a blockbuster drug that transformed the treatment of depression – and became a cultural phenomenon in the United States. Specifically, we chronicle the: 1) prior treatments for depression and the research that...
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Keywords:
Health Care and Treatment;
Technological Innovation;
Innovation Strategy;
Technology Adoption;
Collaborative Innovation and Invention;
Innovation and Invention;
Governing Rules, Regulations, and Reforms
Bhidé, Amar, Srikant M. Datar, and Katherine Stebbins. "SSRIs and Non-SSRIs (through 1999): Case Histories of Significant Medical Advances." Harvard Business School Working Paper, No. 20-135, July 2020. (Revised June 2021.)
- 2021
- Working Paper
Tamoxifen: Case Histories of Significant Medical Advances
By: Amar Bhidé, Srikant Datar and Katherine Stebbins
Our case history describes the development of tamoxifen, considered a “gold standard” treatment for millions of breast cancer patients. Specifically, we describe breast cancer treatments prior to tamoxifen’s development; the initial development of tamoxifen from 1960...
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Keywords:
Health Care and Treatment;
Technological Innovation;
Innovation and Invention;
Innovation Strategy;
Technology Adoption;
Collaborative Innovation and Invention;
Governing Rules, Regulations, and Reforms
Bhidé, Amar, Srikant Datar, and Katherine Stebbins. "Tamoxifen: Case Histories of Significant Medical Advances." Harvard Business School Working Paper, No. 20-134, July 2020. (Revised May 2021.)
- 2020
- Book
Fit to Compete: Why Honest Conversations About Your Company's Capabilities Are the Key to a Winning Strategy
By: Michael Beer
Is Silence Killing Your Strategy?
In his thirty years of working in corporations, Harvard Business School professor Michael Beer has witnessed firsthand how organizational silence derails strategic objectives. When employees can't speak truth to power, senior... View Details
In his thirty years of working in corporations, Harvard Business School professor Michael Beer has witnessed firsthand how organizational silence derails strategic objectives. When employees can't speak truth to power, senior... View Details
Keywords:
Honesty;
Communication;
Organizational Culture;
Trust;
Strategy;
Performance Effectiveness
Beer, Michael. Fit to Compete: Why Honest Conversations About Your Company's Capabilities Are the Key to a Winning Strategy. Boston: Harvard Business Review Press, 2020.
- 2020
- Working Paper
Cutting the Gordian Knot of Employee Health Care Benefits and Costs: A Corporate Model Built on Employee Choice
By: Regina E. Herzlinger and Barak D. Richman
The U.S. employer-based health insurance tax exclusion created a system of employer-sponsored insurance (ESI) with limited insurance choices and transparency that may lock employed households into health plans that are costlier or different from those they prefer to...
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Keywords:
After-tax Income;
Consumer-driven Health Care;
Health Care Costs;
Health Insurance;
Income Inequality;
Tax Policy;
Health Care and Treatment;
Cost;
Insurance;
Employees;
Income;
Taxation;
Policy;
United States
Herzlinger, Regina E., and Barak D. Richman. "Cutting the Gordian Knot of Employee Health Care Benefits and Costs: A Corporate Model Built on Employee Choice." Duke Law School Public Law & Legal Theory Series, No. 2020-4, December 2019. (Revised January 2021.)
- September 2019 (Revised August 2020)
- Case
Engineering an Inclusive Bioeconomy
By: Tarun Khanna, Raffaella Sadun and Susie L. Ma
In 2019, entrepreneur Juan Carlos Castilla-Rubio was developing a project he hoped could generate and share wealth from the natural resources of the Amazon without destroying those resources. His idea, called Earth Bank of Codes (EBC), would create a library of the...
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Keywords:
Decision Making;
Development Economics;
Entrepreneurship;
Innovation and Invention;
Intellectual Property;
Emerging Markets;
Market Design;
Marketplace Matching;
Science;
Genetics;
Natural Environment;
Environmental Sustainability;
Climate Change;
Social Enterprise;
Strategy;
Strategic Planning;
Information Technology;
Ownership;
Social Psychology;
Trust;
Society;
Biotechnology Industry;
South America;
Amazon Basin
Khanna, Tarun, Raffaella Sadun, and Susie L. Ma. "Engineering an Inclusive Bioeconomy." Harvard Business School Case 720-356, September 2019. (Revised August 2020.)
- 2019
- Working Paper
Soul and Machine (Learning)
By: Davide Proserpio, John R. Hauser, Xiao Liu, Tomomichi Amano, Alex Burnap, Tong Guo, Dokyun Lee, Randall Lewis, Kanishka Misra, Eric Schwarz, Artem Timoshenko, Lilei Xu and Hema Yoganarasimhan
Machine learning is bringing us self-driving cars, improved medical diagnostics, and machine translation, but can it improve marketing decisions? It can. Machine learning models predict extremely well, are scalable to “big data,” and are a natural fit to rich media...
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Proserpio, Davide, John R. Hauser, Xiao Liu, Tomomichi Amano, Alex Burnap, Tong Guo, Dokyun Lee, Randall Lewis, Kanishka Misra, Eric Schwarz, Artem Timoshenko, Lilei Xu, and Hema Yoganarasimhan. "Soul and Machine (Learning)." Harvard Business School Working Paper, No. 20-036, September 2019.
- 2021
- Working Paper
Coronary Artery Bypass Grafting: Case Histories of Significant Medical Advances
By: Amar Bhidé, Srikant M. Datar and Fabio Villa
We describe how Coronary Artery Bypass Grafting (CABG, or more popularly, “bypass”) operations revolutionized the treatment of coronary disease (that can produce fatal heart attacks and debilitating angina). We first provide a simplified overview of coronary disease...
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Keywords:
Health Care and Treatment;
Technological Innovation;
Innovation Strategy;
Technology Adoption;
Collaborative Innovation and Invention;
Innovation and Invention;
Governing Rules, Regulations, and Reforms
Bhidé, Amar, Srikant M. Datar, and Fabio Villa. "Coronary Artery Bypass Grafting: Case Histories of Significant Medical Advances." Harvard Business School Working Paper, No. 20-010, July 2019. (Revised May 2021.)
- 2021
- Working Paper
Laparoscopy: Case Histories of Significant Medical Advances
By: Amar Bhidé, Caitlin N. Bowler and Srikant M. Datar
We describe how operations through laparoscopes—tubular instruments inserted into abdominal cavities—revolutionized gynecological and other surgeries inside the abdomen such as gall bladder removal. Specifically, we chronicle the: 1) foundational technologies and...
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Keywords:
Health Care and Treatment;
Technological Innovation;
Innovation Strategy;
Technology Adoption;
Collaborative Innovation and Invention;
Innovation and Invention;
Governing Rules, Regulations, and Reforms
Bhidé, Amar, Caitlin N. Bowler, and Srikant M. Datar. "Laparoscopy: Case Histories of Significant Medical Advances." Harvard Business School Working Paper, No. 20-008, July 2019. (Revised May 2021.)
- 2021
- Working Paper
Who Do We Invent for? Patents by Women Focus More on Women's Health, but Few Women Get to Invent
By: Rembrand Koning, Sampsa Samila and John-Paul Ferguson
Has the increase in female medical researchers led to more medical advances for women? In this paper, we investigate if the gender of inventors shapes their types of inventions. Using data on the universe of U.S. biomedical patents, we find that patents with women...
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Keywords:
Innovation;
Biomedical Research;
Innovation and Invention;
Diversity;
Gender;
Research;
Health;
United States
Koning, Rembrand, Sampsa Samila, and John-Paul Ferguson. "Who Do We Invent for? Patents by Women Focus More on Women's Health, but Few Women Get to Invent." Working Paper. (Harvard Business School Working Paper, No. 19-124, June 2019; SSRN Working Paper Series, No. 3401889, June 2019.)
- April 2019
- Article
Incentives for Public Goods Inside Organizations: Field Experimental Evidence
By: Andrea Blasco, Olivia S. Jung, Karim R. Lakhani and Michael Menietti
Understanding why employees go the extra mile at work is a key problem for many organizations. We conduct a field experiment at a medical organization to study motivations for employees to submit project proposals for organizational improvement. In total, we analyze...
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Keywords:
Field Experiment;
Innovation;
Contest;
Incentives;
Free-rider Problem;
Healthcare Organizations;
Employees;
Motivation and Incentives;
Innovation and Invention;
Organizations;
Performance Improvement;
Perspective
Blasco, Andrea, Olivia S. Jung, Karim R. Lakhani, and Michael Menietti. "Incentives for Public Goods Inside Organizations: Field Experimental Evidence." Journal of Economic Behavior & Organization 160 (April 2019): 214–229.
- March 2019 (Revised April 2021)
- Case
The DivaCup: Navigating Distribution and Growth
By: Ayelet Israeli
When the mother-daughter founders of DivaCup set out with a mission to disrupt the menstrual care industry with an innovative product form, they initially struggled to gain legitimacy and convince retailers to carry their unique product. Fifteen years later, the...
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Keywords:
Female;
Female Ceo;
Female Entrepreneur;
Female Protagonist;
Health & Wellness;
Healthcare;
Price Policies;
Minimum Advertised Price;
Differentiation;
Positioning;
Growth;
Health;
Health Care and Treatment;
Price;
Disruption;
Distribution;
Distribution Channels;
Competitive Strategy;
Competition;
Growth Management;
Mission and Purpose;
Product Development;
Product Marketing;
Product Launch;
Product Positioning;
Advertising;
Business Startups;
Internet and the Web;
Entrepreneurship;
Social Entrepreneurship;
Social Issues;
Social Enterprise;
Medical Devices and Supplies Industry;
Medical Devices and Supplies Industry;
Medical Devices and Supplies Industry;
Medical Devices and Supplies Industry;
Medical Devices and Supplies Industry;
Medical Devices and Supplies Industry;
Medical Devices and Supplies Industry;
Medical Devices and Supplies Industry;
Canada;
United States;
United Kingdom
Israeli, Ayelet. "The DivaCup: Navigating Distribution and Growth." Harvard Business School Case 519-055, March 2019. (Revised April 2021.)
- September 2018
- Article
An Exploratory Study of Product Development in Emerging Economies: Evidence from Medical Device Testing in India
By: Budhaditya Gupta and Stefan Thomke
Recent research has studied innovation in emerging economies. However, microlevel product development processes in these economies are relatively unexplored, and the mechanisms by which the emerging economy context might affect such processes are still unclear. In this...
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Keywords:
India;
Product Development;
Emerging Markets;
Situation or Environment;
Medical Devices and Supplies Industry;
India
Gupta, Budhaditya, and Stefan Thomke. "An Exploratory Study of Product Development in Emerging Economies: Evidence from Medical Device Testing in India." R&D Management 48, no. 4 (September 2018): 485–501.
- July–August 2018
- Article
When Technology Gets Ahead of Society
By: Tarun Khanna
New technologies can be unsettling for industry incumbents, regulators, and consumers, because norms and institutions for dealing with them don’t yet exist. Interestingly, businesspeople in emerging economies face similar challenges: The rules are unclear and...
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Keywords:
Technological Innovation;
Society;
Situation or Environment;
Infrastructure;
Entrepreneurship;
Performance Effectiveness;
Cooperation
Khanna, Tarun. "When Technology Gets Ahead of Society." Harvard Business Review 96, no. 4 (July–August 2018): 86–95.
- Article
A Field Experiment on Search Costs and the Formation of Scientific Collaborations
By: Kevin Boudreau, Tom Brady, Ina Ganguli, Patrick Gaule, Eva C. Guinan, Anthony Hollenberg and Karim R. Lakhani
We present the results of a field experiment conducted at Harvard Medical School to understand the extent to which search costs affect matching among scientific collaborators. We generated exogenous variation in search costs for pairs of potential collaborators by...
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Keywords:
Search Costs;
Cost;
Marketplace Matching;
Groups and Teams;
Science;
Collaborative Innovation and Invention
Boudreau, Kevin, Tom Brady, Ina Ganguli, Patrick Gaule, Eva C. Guinan, Anthony Hollenberg, and Karim R. Lakhani. "A Field Experiment on Search Costs and the Formation of Scientific Collaborations." Review of Economics and Statistics 99, no. 4 (October 2017): 565–576.
- August 2017
- Case
RoboTech: Storming into the U.S. Market
By: Christopher A. Bartlett, Rachel Gordon and John J. Lafkas
This case describes the challenges facing the CEO of a small, Singapore-based industrial robotics company that decides to diversify away from its core industrial robot business by leveraging its expertise into the medical-devices industry. It launches an innovative...
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Keywords:
Market Entry and Exit;
Diversification;
Product Launch;
Competitive Strategy;
Globalized Firms and Management;
Medical Devices and Supplies Industry;
Medical Devices and Supplies Industry;
Singapore;
United States
Bartlett, Christopher A., Rachel Gordon, and John J. Lafkas. "RoboTech: Storming into the U.S. Market." Harvard Business School Brief Case 918-501, August 2017.
- 2017
- Working Paper
Tort Reform and Innovation
By: Alberto Galasso and Hong Luo
Current academic and policy debates focus on the impact of tort reforms on physicians’ behavior and medical costs. This paper examines whether these reforms also affect incentives to develop new technologies. We develop a theoretical model which predicts that the...
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Keywords:
Lawsuits and Litigation;
Laws and Statutes;
Innovation and Invention;
Medical Devices and Supplies Industry
Galasso, Alberto, and Hong Luo. "Tort Reform and Innovation." Working Paper, August 2017. (Accepted for publication in Journal of Law and Economics.)
- August 2017
- Article
Tort Reform and Innovation
By: Alberto Galasso and Hong Luo
Current academic and policy debates focus on the impact of tort reforms on physicians’ behavior and medical costs. This paper examines whether these reforms also affect incentives to develop new technologies. We develop a theoretical model that predicts that the impact...
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Keywords:
Governing Rules, Regulations, and Reforms;
Health Care and Treatment;
Technological Innovation;
Legal Liability;
Medical Devices and Supplies Industry
Galasso, Alberto, and Hong Luo. "Tort Reform and Innovation." Journal of Law & Economics 60, no. 3 (August 2017): 385–412.
- July 2017 (Revised October 2017)
- Supplement
Becton Dickinson: Innovation and Growth (B)
By: Raffaella Sadun, Michael Beer and James Weber
This (B) case supplements the (A) case by providing additional information and updates through early 2016.
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Keywords:
Transformation;
Change Management;
Innovation Leadership;
Mergers and Acquisitions;
Organizational Change and Adaptation;
Organizational Culture;
Organizational Design;
Strategy;
Medical Devices and Supplies Industry;
Medical Devices and Supplies Industry;
Medical Devices and Supplies Industry;
United States
Sadun, Raffaella, Michael Beer, and James Weber. "Becton Dickinson: Innovation and Growth (B)." Harvard Business School Supplement 717-504, July 2017. (Revised October 2017.)
- June 2017 (Revised October 2017)
- Case
Becton Dickinson: Innovation and Growth (A)
By: Raffaella Sadun, Michael Beer and James Weber
In late 2015, CEO Vince Forlenza was reviewing Becton Dickinson’s transformation efforts designed to enable the company to innovate and grow in a changing environment. Becton Dickinson had been a successful medical device company for over 100 years. In recent years,...
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Keywords:
Transformation;
Change Management;
Innovation Leadership;
Mergers and Acquisitions;
Organizational Change and Adaptation;
Organizational Culture;
Organizational Design;
Strategy;
Growth and Development Strategy;
Medical Devices and Supplies Industry;
Medical Devices and Supplies Industry;
Medical Devices and Supplies Industry;
United States
Sadun, Raffaella, Michael Beer, and James Weber. "Becton Dickinson: Innovation and Growth (A)." Harvard Business School Case 717-419, June 2017. (Revised October 2017.)
- May 2017 (Revised June 2017)
- Case
ATH Technologies (A): Making the Numbers
By: Robert Simons and Jennifer Packard
An exercise that takes students through five stages of growth in an entrepreneurial start-up in the medical devices industry: 1) founding, 2) growth, 3) push to profitability, 4) refocusing process, and 5) takeover by new management. At each stage, students must...
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Keywords:
Strategy And Execution;
Management Control Systems;
Balancing Innovation And Control;
Performance Management;
Business Growth and Maturation;
Business Startups;
Profit;
Geographic Location;
Governance Controls;
Innovation and Invention;
Management Succession;
Performance Evaluation;
Medical Devices and Supplies Industry
Simons, Robert, and Jennifer Packard. "ATH Technologies (A): Making the Numbers." Harvard Business School Case 117-013, May 2017. (Revised June 2017.)