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All HBS Web
(1,143)
- Faculty Publications (276)
- Article
Use of Connected Digital Products in Clinical Research Following the COVID-19 Pandemic: A Comprehensive Analysis of Clinical Trials
By: Caroline Marra, William J. Gordon and Ariel Dora Stern
Objectives: In an effort to mitigate COVID-19 related challenges for clinical research, the U.S. Food and Drug Administration (FDA) issued new guidance for the conduct of ‘virtual’ clinical trials in late March 2020. This study documents trends in the use of...
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Keywords:
Connected Digital Products;
Telehealth;
Remote Monitoring;
Health Testing and Trials;
Research;
Governing Rules, Regulations, and Reforms;
Information Technology
Marra, Caroline, William J. Gordon, and Ariel Dora Stern. "Use of Connected Digital Products in Clinical Research Following the COVID-19 Pandemic: A Comprehensive Analysis of Clinical Trials." BMJ Open 11, no. 6 (2021).
- 2021
- Working Paper
Venture Capital's 'Me Too' Moment
By: Sophie Calder-Wang, Paul A. Gompers and Patrick Sweeney
In this paper, we document the historically low rate of hiring of women in the venture capital sector. We find that the high-profile Ellen Pao v. Kleiner Perkins gender discrimination trial had dramatic treatment effects. In difference-in-differences regressions, we...
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Keywords:
Gender Discrimination;
Founders;
Venture Capital;
Selection and Staffing;
Gender;
Lawsuits and Litigation
Calder-Wang, Sophie, Paul A. Gompers, and Patrick Sweeney. "Venture Capital's 'Me Too' Moment." NBER Working Paper Series, No. 28679, April 2021.
- Article
Ushering in Safe, Effective, Secure, and Ethical Medicine in the Digital Era
By: William J. Gordon, Andrea Coravos and Ariel Dora Stern
From clinical trials to care delivery, advanced, digitally enabled technologies and analytics offer new approaches to how we think about medicine, health, and biology. The COVID-19 pandemic has accelerated this conversation, and forced a roadmap, once measured in years...
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Gordon, William J., Andrea Coravos, and Ariel Dora Stern. "Ushering in Safe, Effective, Secure, and Ethical Medicine in the Digital Era." npj Digital Medicine 4, no. 56 (2021).
- February 2021
- Article
The Department of Justice as a Gatekeeper in Whistleblower-Initiated Corporate Fraud Enforcement: Drivers and Consequences
By: Jonas Heese, Ranjani Krishnan and Hari Ramasubramanian
We examine drivers and consequences of U.S. Department of Justice (DOJ) oversight of whistleblower cases of corporate fraud against the government. We find that the DOJ is more likely to intervene in and conduct longer investigations of cases that have a higher chance...
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Keywords:
Whistleblowing;
Department Of Justice;
DOJ Enforcement;
Performance Measures;
False Claims Act;
Crime and Corruption;
Governance Compliance;
Law Enforcement
Heese, Jonas, Ranjani Krishnan, and Hari Ramasubramanian. "The Department of Justice as a Gatekeeper in Whistleblower-Initiated Corporate Fraud Enforcement: Drivers and Consequences." Journal of Accounting & Economics 71, no. 1 (February 2021).
- 2021
- Working Paper
The Health Costs of Cost-Sharing
By: Amitabh Chandra, Evan Flack and Ziad Obermeyer
We use the design of Medicare’s prescription drug benefit program to demonstrate three facts about the health consequences of cost-sharing. First, we show that an as-if-random increase of 33.6% in out-of-pocket price (11.0 percentage points (p.p.) change in...
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Chandra, Amitabh, Evan Flack, and Ziad Obermeyer. "The Health Costs of Cost-Sharing." NBER Working Paper Series, No. 28439, February 2021.
- February 2021
- Article
Trust and Disintermediation: Evidence from an Online Freelance Marketplace
By: Grace Gu and Feng Zhu
As an intermediary improves trust between the two sides of its market to facilitate matching and transactions, it faces an increased risk of disintermediation: with sufficient trust, the two sides may circumvent the intermediary to avoid the intermediary’s fees. In...
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Keywords:
Disintermediation;
Intermediaries;
Online Marketplace;
Platform Strategy;
Trust;
Marketplace Matching;
Digital Platforms
Gu, Grace, and Feng Zhu. "Trust and Disintermediation: Evidence from an Online Freelance Marketplace." Management Science 67, no. 2 (February 2021): 794–807.
- January 2021 (Revised August 2021)
- Case
ByteDance: TikTok and the Trials of Going Viral
By: William C. Kirby and John P. McHugh
In 2020, TikTok became the most valuable start-up ever. The short-form, video-sharing social media platform emerged as the crown jewel of the Chinese technology firm ByteDance, realizing 850 million monthly users and an estimated worth of $180 billion. However, a...
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Keywords:
China;
Technology;
Startup;
Start-up;
International Strategy;
Global Strategy And Leadership;
Innovation;
Political Risk;
Regulations;
Trump;
Foreign Policy;
Foreign Investment;
Chinese Internet Market;
Global Strategy;
Crisis Management;
Risk and Uncertainty;
Entrepreneurship;
Globalized Economies and Regions;
Government Legislation;
Innovation and Management;
Governing Rules, Regulations, and Reforms;
Internet and the Web;
Social Media;
Technology Industry;
China;
United States
Kirby, William C., and John P. McHugh. "ByteDance: TikTok and the Trials of Going Viral." Harvard Business School Case 321-110, January 2021. (Revised August 2021.)
- June 2021
- Article
From Predictions to Prescriptions: A Data-driven Response to COVID-19
By: Dimitris Bertsimas, Léonard Boussioux, Ryan Cory-Wright, Arthur Delarue, Vassilis Digalakis Jr, Alexander Jacquillat, Driss Lahlou Kitane, Galit Lukin, Michael Lingzhi Li, Luca Mingardi, Omid Nohadani, Agni Orfanoudaki, Theodore Papalexopoulos, Ivan Paskov, Jean Pauphilet, Omar Skali Lami, Bartolomeo Stellato, Hamza Tazi Bouardi, Kimberly Villalobos Carballo, Holly Wiberg and Cynthia Zeng
The COVID-19 pandemic has created unprecedented challenges worldwide. Strained healthcare providers make difficult decisions on patient triage, treatment and care management on a daily basis. Policy makers have imposed social distancing measures to slow the disease, at...
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Keywords:
COVID-19;
Health Pandemics;
AI and Machine Learning;
Forecasting and Prediction;
Analytics and Data Science
Bertsimas, Dimitris, Léonard Boussioux, Ryan Cory-Wright, Arthur Delarue, Vassilis Digalakis Jr, Alexander Jacquillat, Driss Lahlou Kitane, Galit Lukin, Michael Lingzhi Li, Luca Mingardi, Omid Nohadani, Agni Orfanoudaki, Theodore Papalexopoulos, Ivan Paskov, Jean Pauphilet, Omar Skali Lami, Bartolomeo Stellato, Hamza Tazi Bouardi, Kimberly Villalobos Carballo, Holly Wiberg, and Cynthia Zeng. "From Predictions to Prescriptions: A Data-driven Response to COVID-19." Health Care Management Science 24, no. 2 (June 2021): 253–272.
- December 2020 (Revised January 2022)
- Supplement
Michael Ku and Global Clinical Supply at Pfizer Inc.: Bringing Hope to Patients (B)
By: Linda A. Hill and Emily Tedards
In 2011, Michael Ku became Pfizer’s Vice President of Global Clinical Supply (GCS) after the company had undergone three large-scale mergers and acquisitions. As Ku and his new leadership team set out to build a proactive, end-to-end, digital and physical clinical...
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Keywords:
Digital Technology;
Customer-centricity;
Innovation;
Customer Focus;
Talent;
Talent Management;
Leadership;
Innovation and Invention;
Transformation;
Organizational Culture;
Customer Focus and Relationships;
Change Management;
Talent and Talent Management;
Supply Chain;
Mission and Purpose
Hill, Linda A., and Emily Tedards. "Michael Ku and Global Clinical Supply at Pfizer Inc.: Bringing Hope to Patients (B)." Harvard Business School Supplement 421-037, December 2020. (Revised January 2022.)
- December 2020
- Supplement
France Télécom (C): An Unprecedented Trial
In the C case we learn that former CEO Didier Lombard, Deputy Chief Executive Louis-Pierre Wenes, Human Resources Head Olivier Barberot and France Telecom itself were charged for institutional harassment by French authorities, a first for a CAC 40 company. In December...
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Keywords:
Human Behavior;
Human Dignity;
Human Resource Practices;
Corporate Change And Sustainability;
Corporate Culture;
Strategic Corporate Decisions;
Strategic Change;
Strategic Decision Making;
Emotion;
Management Challenges;
Corporate Accountability;
Organizational Culture;
Human Resources;
Crisis Management;
Law;
Courts and Trials;
Labor;
Labor and Management Relations;
Management Practices and Processes;
Employees;
Well-being;
Telecommunications Industry;
Europe;
European Union
Montgomery, Cynthia A., and Ashley V. Whillans. "France Télécom (C): An Unprecedented Trial." Harvard Business School Supplement 721-422, December 2020.
- November 2020
- Teaching Note
DayTwo: Going to Market with Gut Microbiome
By: Ayelet Israeli
Teaching Note for HBS Case No. 519-010. DayTwo is a young Israeli startup that applies research on the gut microbiome and machine learning algorithms to deliver personalized nutritional recommendations to its users in order to minimize blood sugar spikes after meals....
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Keywords:
Start-up Growth;
Startup;
Positioning;
Targeting;
Go To Market Strategy;
B2B Vs. B2C;
B2B2C;
Health & Wellness;
AI;
Machine Learning;
Female Ceo;
Female Protagonist;
Science-based;
Science And Technology Studies;
Ecommerce;
Applications;
DTC;
Direct To Consumer Marketing;
US Health Care;
"USA,";
Innovation;
Pricing;
Business Growth;
Segmentation;
Distribution Channels;
Growth and Development Strategy;
Business Startups;
Science-Based Business;
Health;
Innovation and Invention;
Marketing;
Information Technology;
Business Growth and Maturation;
E-commerce;
Applications and Software;
Food and Beverage Industry;
Food and Beverage Industry;
Food and Beverage Industry;
Food and Beverage Industry;
Food and Beverage Industry;
Israel;
United States
- 2023
- Working Paper
Personalized Game Design for Improved User Retention and Monetization in Freemium Games
By: Eva Ascarza, Oded Netzer and Julian Runge
One of the most crucial aspects and significant levers that gaming companies possess in designing
digital games is setting the level of difficulty, which essentially regulates the user’s ability to
progress within the game. This aspect is particularly significant in...
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Keywords:
Freemium;
Retention/churn;
Field Experiment;
Field Experiments;
Gaming;
Gaming Industry;
Mobile App;
Mobile App Industry;
Monetization;
Monetization Strategy;
Games, Gaming, and Gambling;
Mobile and Wireless Technology;
Customers;
Retention;
Product Design;
Strategy
Ascarza, Eva, Oded Netzer, and Julian Runge. "Personalized Game Design for Improved User Retention and Monetization in Freemium Games." Harvard Business School Working Paper, No. 21-062, November 2020. (Revised December 2023.)
- October 2020
- Teaching Plan
Merck: COVID-19 Vaccines
By: Willy C. Shih
COVID-19 infections were still climbing across the U.S. and many other parts of the world in September 2020, and it seemed that every time Ken Frazier, the CEO of Merck & Co. consented to an interview in recent months he always seemed to hear the same question,...
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- October 2020 (Revised November 2023)
- Case
COVID-19 Testing at Everlywell
By: Jeffrey J. Bussgang and Olivia Hull
In March 2020, as COVID-19 spreads rapidly across the U.S., Everlywell founder Julia Cheek considers how to respond as a small start-up specializing in at-home lab testing. After making dramatic budget cuts, she decides to pivot the organization to address the...
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Keywords:
Entrepreneurship;
Business Strategy;
Venture Capital;
Health Care and Treatment;
Health Disorders;
Leading Change;
Technology Adoption;
Digital Platforms;
Competitive Strategy;
Science;
Adaptation;
Corporate Social Responsibility and Impact;
Crisis Management;
Social Entrepreneurship;
Ethics;
Government Legislation;
Health;
Health Testing and Trials;
Health Pandemics;
Consumer Products Industry;
Health Industry;
Technology Industry;
Texas;
United States
Bussgang, Jeffrey J., and Olivia Hull. "COVID-19 Testing at Everlywell." Harvard Business School Case 821-001, October 2020. (Revised November 2023.)
- Fall 2020
- Article
Sizing Up Corporate Restructuring in the COVID Crisis
By: Robin Greenwood, Benjamin Iverson and David Thesmar
In the wake of the COVID-19 pandemic, the financial and legal system will need to deal with a surge of financial distress in the business sector. Some firms will be able to survive, while others will face bankruptcy and thus need to be liquidated or reorganized. Many...
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Greenwood, Robin, Benjamin Iverson, and David Thesmar. "Sizing Up Corporate Restructuring in the COVID Crisis." Brookings Papers on Economic Activity (Fall 2020). (Also NBER Working Paper, No. 28104.)
- September 2020
- Case
Merck: COVID-19 Vaccines
By: Willy C. Shih
COVID-19 infections were still climbing across the U.S. and many other parts of the world in September 2020, and it seemed that every time Ken Frazier, the CEO of Merck & Co. consented to an interview in recent months he always seemed to hear the same question,...
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Keywords:
Vaccines;
COVID-19 Pandemic;
Health Pandemics;
Health Testing and Trials;
Innovation and Management;
Innovation Strategy;
Technological Innovation;
Business Strategy;
Product Launch;
Pharmaceutical Industry
Shih, Willy C. "Merck: COVID-19 Vaccines." Harvard Business School Case 621-028, September 2020.
- September 2020
- Case
Disrupting Justice at RightNow: Persevere, Pivot or Perish
By: Shikhar Ghosh and Amir Reza Rezvani
The case examines the focus of an early stage company, and how an unexpected external incidence can threaten or void the business model. It encompasses issues such as defining and pivoting a business model, organizational requirements for a pivot, investor relations,...
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Keywords:
Legal Aspects Of Business;
Startup;
Teams;
Pivot;
Financing;
Entrepreneurship;
Law;
Venture Capital;
Business Startups;
Financing and Loans;
Business Model;
Organizational Change and Adaptation;
Legal Services Industry;
Germany
Ghosh, Shikhar, and Amir Reza Rezvani. "Disrupting Justice at RightNow: Persevere, Pivot or Perish." Harvard Business School Case 821-027, September 2020.
- September 2020 (Revised September 2021)
- Supplement
Student Success at Georgia State University (B)
By: Michael W. Toffel, Robin Mendelson and Julia Kelley
This is a supplement to the Student Success at Georgia State University (A) case. The (B) case includes the results of a randomized control trial that Georgia State conducted to test education technology start-up AdmitHub’s chatbot solution as a strategy for improving...
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Keywords:
Education;
Higher Education;
Learning;
Curriculum and Courses;
Demographics;
Diversity;
Ethnicity;
Income;
Race;
Values and Beliefs;
Leadership;
Goals and Objectives;
Measurement and Metrics;
Operations;
Organizations;
Mission and Purpose;
Organizational Culture;
Outcome or Result;
Performance;
Performance Effectiveness;
Performance Evaluation;
Performance Improvement;
Planning;
Strategic Planning;
Social Enterprise;
Nonprofit Organizations;
Social Issues;
Wealth and Poverty;
Equality and Inequality;
Information Technology;
Digital Platforms;
Education Industry;
Atlanta
Toffel, Michael W., Robin Mendelson, and Julia Kelley. "Student Success at Georgia State University (B)." Harvard Business School Supplement 621-039, September 2020. (Revised September 2021.)
- 2020
- Working Paper
(When) Does Appearance Matter? Evidence from a Randomized Controlled Trial
By: Prithwiraj Choudhury, Tarun Khanna, Christos A. Makridis and Subhradip Sarker
While there is evidence about labor market discrimination based on race, religion, and gender, we know little about whether physical appearance leads to discrimination in labor market outcomes. We deploy a randomized experiment on 1,000 respondents in India between...
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Keywords:
Behavioral Economics;
Coronavirus;
Discrimination;
Homophily;
Labor Market Mobility;
Limited Attention;
Resumes;
Personal Characteristics;
Prejudice and Bias
Choudhury, Prithwiraj, Tarun Khanna, Christos A. Makridis, and Subhradip Sarker. "(When) Does Appearance Matter? Evidence from a Randomized Controlled Trial." Harvard Business School Working Paper, No. 21-038, September 2020.
- September–October 2020
- Article
The Past, Present, and (Near) Future of Gene Therapy and Gene Editing
By: Julia Pian, Amitabh Chandra and Ariel Dora Stern
Emerging gene therapy and gene-editing technologies will have a growing impact on patient lives and health-care delivery. We analyzed a decade of data on clinical trials and venture capital investments to understand the likely trajectory of genetically focused...
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Keywords:
Gene Therapy;
Gene Editing;
Impact;
Health Care and Treatment;
Technological Innovation;
Health Testing and Trials;
Venture Capital;
Change
Pian, Julia, Amitabh Chandra, and Ariel Dora Stern. "The Past, Present, and (Near) Future of Gene Therapy and Gene Editing." NEJM Catalyst Innovations in Care Delivery 1, no. 5 (September–October 2020).