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- People (1)
- News (82)
- Research (185)
- Multimedia (3)
- Faculty Publications (123)
Show Results For
-
All HBS Web
(299)
- People (1)
- News (82)
- Research (185)
- Multimedia (3)
- Faculty Publications (123)
- Research Summary
Current Research Projects
1. Freedom and Openness in Scientific Research
This is a joint project with Philippe Aghion, Scott Stern, and Fiona Murray. It analyzes the effects of shifts in the availability of genetically modified mice for follow-on research. ... View Details
- October 2020
- Case
Genomics in the Family Office
By: Lauren Cohen, Ronnie Stangler and Spencer C. N. Hagist
Alice Anane is the member of a large, wealthy family that collectively operates a multi-pronged family business in Israel. Upon discovering partway into her pregnancy that the rapidly degenerative brain disease her father succumbed to now threatens her and potentially...
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Cohen, Lauren, Ronnie Stangler, and Spencer C. N. Hagist. "Genomics in the Family Office." Harvard Business School Case 221-035, October 2020.
- 17 Oct 2018
- Video
Unlocking the Potential of Precision Medicine
- September 2017 (Revised February 2023)
- Case
Intermountain Healthcare: Pursuing Precision Medicine
By: Richard G. Hamermesh, Kathy E. Giusti, Robert S. Huckman and Julia Kelley
Headquartered in Salt Lake City, Intermountain Healthcare operates 23 hospitals and hundreds of clinics in Utah and Idaho and provides insurance to approximately 850,000 patients through its insurance arm, SelectHealth. In 2013, Intermountain, known for its commitment...
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Keywords:
Precision Medicine;
Healthcare;
Innovation;
Cancer;
Cancer Research;
Health Care;
Technology;
Health Care and Treatment;
Innovation Leadership;
Disruptive Innovation;
Entrepreneurship;
Decision Choices and Conditions;
Health Industry;
Insurance Industry;
Utah;
United States;
North America
Hamermesh, Richard G., Kathy E. Giusti, Robert S. Huckman, and Julia Kelley. "Intermountain Healthcare: Pursuing Precision Medicine." Harvard Business School Case 818-018, September 2017. (Revised February 2023.)
- March 2012 (Revised October 2013)
- Supplement
Gene Patents (B)
By: Richard Hamermesh and Phillip Andrews
The case updates events since the Court's ruling against Myriad Genetics on March 29, 2010 and should be used in conjunction with Gene Patents (A). On July 29, 2011, a US Appeals Court reversed the prior ruling against Myriad. On September 16, 2011, the first major...
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Keywords:
Courts and Trials;
Patents;
Genetics;
Judgments;
Investment;
Biotechnology Industry;
United States
Hamermesh, Richard, and Phillip Andrews. "Gene Patents (B)." Harvard Business School Supplement 812-130, March 2012. (Revised October 2013.)
- May 2006 (Revised June 2006)
- Case
Codon Devices
By: Joseph B. Lassiter III and David Kiron
In December 2005, 40-year-old John Danner was about to make his first presentation to the board of directors of Codon Devices, a one-year-old biotechnology start-up based in Cambridge, Massachusetts. After a month as the company's CEO, Danner was prepared to lay out...
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Keywords:
Strategic Planning;
Venture Capital;
Intellectual Property;
Governing and Advisory Boards;
Genetics;
Competitive Advantage;
Science-Based Business;
Business Startups;
Growth and Development Strategy;
Biotechnology Industry;
Cambridge
Lassiter, Joseph B., III, and David Kiron. "Codon Devices." Harvard Business School Case 806-198, May 2006. (Revised June 2006.)
- September–October 2020
- Article
The Past, Present, and (Near) Future of Gene Therapy and Gene Editing
By: Julia Pian, Amitabh Chandra and Ariel Dora Stern
Emerging gene therapy and gene-editing technologies will have a growing impact on patient lives and health-care delivery. We analyzed a decade of data on clinical trials and venture capital investments to understand the likely trajectory of genetically focused...
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Keywords:
Gene Therapy;
Gene Editing;
Impact;
Health Care and Treatment;
Technological Innovation;
Health Testing and Trials;
Venture Capital;
Change
Pian, Julia, Amitabh Chandra, and Ariel Dora Stern. "The Past, Present, and (Near) Future of Gene Therapy and Gene Editing." NEJM Catalyst Innovations in Care Delivery 1, no. 5 (September–October 2020).
- 2016
- Chapter
Deriving an Optimally Deceptive Policy in Two-Player Iterated Games
By: Elisabeth Paulson and Christopher Griffin
We formulate the problem of determining an optimally deceptive strategy in a repeated game framework. We assume that two players are engaged in repeated play. During an initial time period, Player 1 may deceptively train his opponent to expect a specific strategy. The...
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Paulson, Elisabeth, and Christopher Griffin. "Deriving an Optimally Deceptive Policy in Two-Player Iterated Games." In Proceedings of 2016 American Control Conference. IEEE Press, 2016. (Developed with Booz Allen Hamilton.)
- September 2014
- Article
Advancing Consumer Neuroscience
By: Ale Smidts, Ming Hsu, Alan G. Sanfey, Maarten A. S. Boksem, Richard B. Ebstein, Scott A. Huettel, Joe W. Kable, Uma R. Karmarkar, Shinobu Kitayama, Brian Knutson, Israel Liberzon, Terry Lohrenz, Mirre Stallen and Carolyn Yoon
In the first decade of consumer neuroscience, strong progress has been made in understanding how neuroscience can inform consumer decision making. Here, we sketch the development of this discipline and compare it to that of the adjacent field of neuroeconomics. We...
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Keywords:
Consumer Neuroscience;
Neuroeconomics;
Social Neuroscience;
Genes;
Machine Learning;
Meta-analysis;
Consumer Behavior;
Decision Making;
Science
Smidts, Ale, Ming Hsu, Alan G. Sanfey, Maarten A. S. Boksem, Richard B. Ebstein, Scott A. Huettel, Joe W. Kable, Uma R. Karmarkar, Shinobu Kitayama, Brian Knutson, Israel Liberzon, Terry Lohrenz, Mirre Stallen, and Carolyn Yoon. "Advancing Consumer Neuroscience." Marketing Letters 25, no. 3 (September 2014): 257–267.
- July 2000 (Revised April 2001)
- Case
Agricultural Biotechnology and its Regulation
In the United States, genetically modified corn and soybeans are now widely grown and consumed. In Europe, however, they have been dubbed "Frankenstein foods," shunned by packaged food manufacturers, and subjected to a host of governmental restrictions. This case...
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Keywords:
Agribusiness;
Genetics;
Governing Rules, Regulations, and Reforms;
Corporate Strategy;
Trade;
Law;
Goods and Commodities;
Safety;
Environmental Sustainability;
Government and Politics;
Agriculture and Agribusiness Industry;
Biotechnology Industry;
Europe;
United States
Reinhardt, Forest L. "Agricultural Biotechnology and its Regulation." Harvard Business School Case 701-004, July 2000. (Revised April 2001.)
- October 2016 (Revised September 2017)
- Case
The CRISPR-Cas9 Quarrel
By: Richard G. Hamermesh and Matthew G. Preble
In mid-2016, the Broad Institute and the University of California, Berkeley were in the middle of a contentious patent dispute over which entity controlled a breakthrough gene editing technology called CRISPR-Cas9. With CRISPR-Cas9, scientists might soon be able to...
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Keywords:
CRISPR;
Broad Institute;
University Of California Berkeley;
Intellectual Property;
Patents;
Law;
Lawsuits and Litigation;
Science;
Genetics;
Entrepreneurship;
Biotechnology Industry;
United States
Hamermesh, Richard G., and Matthew G. Preble. "The CRISPR-Cas9 Quarrel." Harvard Business School Case 817-020, October 2016. (Revised September 2017.)
- December 2001
- Background Note
Reporting on Agribusiness in the 21st Century
By: Ray A. Goldberg and Anne M Fitzgerald
Agriculture is not what it used to be. Neither is coverage of the industry by news organizations. A century ago, about 40% of the U.S. population lived on the farm, and one in three U.S. jobs was tied to agriculture. It made sense for daily newspapers to cover farming...
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Keywords:
Agribusiness;
Newspapers;
Media;
Perception;
Change;
Agriculture and Agribusiness Industry;
United States
Goldberg, Ray A., and Anne M Fitzgerald. "Reporting on Agribusiness in the 21st Century." Harvard Business School Background Note 902-421, December 2001.
- January 15, 2015
- Article
Surviving in a Family Business When You're Not Part of the Family
By: Josh Baron and Rob Lachenauer
Navigating office politics in a family-owned business can be challenging for non-family executives. Based on experience with various business families worldwide, this article offers strategies for success:
Play in your room: Non-family executives should... View Details
Play in your room: Non-family executives should... View Details
Keywords:
Family Business;
Family and Family Relationships;
Employees;
Problems and Challenges;
Talent and Talent Management
Baron, Josh, and Rob Lachenauer. "Surviving in a Family Business When You're Not Part of the Family." Harvard Business Review (website) (January 15, 2015).
- January 2011 (Revised July 2012)
- Case
Arcadia Biosciences: Seeds of Change (Abridged)
By: Arthur A. Daemmrich
Arcadia Biosciences is seeking to introduce genetically modified rice to China that will lower farmers' costs and generate environmental benefits through reduced greenhouse gas emissions. The case describes challenges facing this small agricultural biotechnology...
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Keywords:
Plant-Based Agribusiness;
Intellectual Property;
Genetics;
Environmental Sustainability;
Science-Based Business;
Climate Change;
Agriculture and Agribusiness Industry;
Biotechnology Industry;
China
Daemmrich, Arthur A. "Arcadia Biosciences: Seeds of Change (Abridged)." Harvard Business School Case 711-050, January 2011. (Revised July 2012.)
- October 2001 (Revised March 2002)
- Case
Perlegen Sciences
By: Linda A. Hill and Nicole Tempest
As a biotech start-up company involved in studying human genomes, Perlegen needed to develop an organization that fostered innovation and teamwork among a group of highly trained professionals from both the science and technology fields. Perlegen's CEO, Brad Margus,...
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Keywords:
Innovation Leadership;
Groups and Teams;
Management Teams;
Problems and Challenges;
Business Startups;
Genetics;
Talent and Talent Management;
Innovation Strategy;
Biotechnology Industry
Hill, Linda A., and Nicole Tempest. "Perlegen Sciences." Harvard Business School Case 402-026, October 2001. (Revised March 2002.)
- Web
Capstone - MBA
guidance across all student interests. While Capstone advisors often include leading experts in their fields, students have the ability to choose capstones across any medical and biotechnology specialty. Recent capstone topics have included bioelectricity,...
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- Web
Curriculum - MBA
concerns about unjust research trials in low resource countries, and uncertainty about the value of genetic testing in drug development and study design will be explored. Pediatric Bioethics Pediatric bioethics addresses the complexities...
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- December 2008 (Revised January 2011)
- Case
Arcadia Biosciences: Seeds of Change
By: Arthur A. Daemmrich, Forest L. Reinhardt and Mary Louise Shelman
Arcadia Biosciences is an entrepreneurial California agricultural biotech company seeking to earn carbon credits by modifying commodity crops for use in China and India. Eric Rey, Arcadia's CEO, faced a strategic inflection point in early September 2008. The company...
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Keywords:
Business Startups;
Entrepreneurship;
Growth and Development Strategy;
Environmental Sustainability;
Science-Based Business;
Climate Change;
Agriculture and Agribusiness Industry;
Biotechnology Industry;
China;
India;
California
Daemmrich, Arthur A., Forest L. Reinhardt, and Mary Louise Shelman. "Arcadia Biosciences: Seeds of Change." Harvard Business School Case 709-019, December 2008. (Revised January 2011.)
- January 2009 (Revised February 2009)
- Case
Sydney IVF: Stem Cell Research
By: Robert L. Simons, Kathryn Rosenberg and Natalie Kindred
This case examines the strategy implementation and risk management decisions at Sydney IVF, a research-based in vitro fertilization and stem cell company based in Australia. Drs. Robert Jansen and Jock Anderson, who co-founded Sydney IVF in 1986, developed novel...
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Keywords:
Ethics;
Governing Rules, Regulations, and Reforms;
Innovation and Management;
Growth and Development Strategy;
Risk Management;
Genetics;
Commercialization;
Health Industry;
Australia
Simons, Robert L., Kathryn Rosenberg, and Natalie Kindred. "Sydney IVF: Stem Cell Research." Harvard Business School Case 109-017, January 2009. (Revised February 2009.)
- February 2014
- Case
BGI: Data-driven Research
By: Willy Shih and Sen Chai
BGI has the largest installed gene-sequencing capacity in the world, and to Zhang Gengyun, general manager of the Life Sciences Division, this represented an opportunity to apply his training as a plant breeder and his early career work as a biochemist to improving...
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Keywords:
Genomics;
Gene Sequencing;
Life Sciences;
Plant Breeding;
Human Genome Program;
Beijing Genomics Institute;
BGI;
Rice Genome;
Technological Innovation;
Innovation Strategy;
Research;
Research and Development;
Science;
Genetics;
Science-Based Business;
Strategy;
Commercialization;
Corporate Strategy;
Information Technology;
Applications and Software;
Agriculture and Agribusiness Industry;
Biotechnology Industry;
Food and Beverage Industry;
China;
United States
Shih, Willy, and Sen Chai. "BGI: Data-driven Research." Harvard Business School Case 614-056, February 2014.