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- Faculty Publications (44)
- November 2019
- Case
The Genesis Lab at Novartis
By: Amy C. Edmondson, Ranjay Gulati, Patrick J. Healy and Kerry Herman
Novartis' Genesis Labs program, launched in 2016 as part of Novartis Institutes for Biomedical Research (NIBR), hosted pitch competitions where teams of NIBR scientists proposed ideas to explore that aimed to revolutionize drug discovery. The goal was to break down...
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Keywords:
Drug Discovery;
Health Care and Treatment;
Research and Development;
Innovation and Invention;
Programs;
Management
Edmondson, Amy C., Ranjay Gulati, Patrick J. Healy, and Kerry Herman. "The Genesis Lab at Novartis." Harvard Business School Case 620-007, November 2019.
- April 2019 (Revised June 2019)
- Case
Ariadne Labs: Building Impactful Partnerships
By: Ariel D. Stern and Sarah Mehta
In September 2018, the executive team at Ariadne Labs (Ariadne), a Boston-based organization dedicated to improving health systems through the discovery and implementation of simple tools, faced a number of strategic decisions. Chief among them, the seven-year-old...
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Keywords:
Health;
Health Care and Treatment;
Innovation and Invention;
Social Enterprise;
Nonprofit Organizations;
Partners and Partnerships;
Health Industry;
Boston
Stern, Ariel D., and Sarah Mehta. "Ariadne Labs: Building Impactful Partnerships." Harvard Business School Case 619-017, April 2019. (Revised June 2019.)
- November 2018 (Revised January 2022)
- Case
JUUL and the Vaping Revolution
By: Michael W. Toffel, John Masko and Sarah Mehta
In late 2019, San Francisco-based electronic cigarette (e-cigarette) maker JUUL Labs (pronounced “jewel”) faced intense pressure. Sales of JUUL products exceeded $1 billion in 2018, dominating the e-cigarette category. While JUUL Labs’ stated goal was to help current...
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Keywords:
Electronic Cigarettes;
E-Cigarettes;
Vaping;
Nicotine Replacement;
JUUL;
Juuling;
Advertising;
Digital Marketing;
Customers;
Innovation and Invention;
Marketing;
Ethics;
Brands and Branding;
Marketing Communications;
Marketing Strategy;
Product Marketing;
Corporate Social Responsibility and Impact;
Social Issues;
Information Technology;
Technology Industry;
San Francisco;
California
Toffel, Michael W., John Masko, and Sarah Mehta. "JUUL and the Vaping Revolution." Harvard Business School Case 619-006, November 2018. (Revised January 2022.)
- October 2018 (Revised July 2019)
- Case
Sidewalk Labs: Privacy in a City Built from the Internet Up
By: Leslie K. John, Mitchell Weiss and Julia Kelley
Email mking@hbs.edu for a courtesy copy.
By the time Dan Doctoroff, CEO of Sidewalk Labs, began hosting a Reddit “Ask Me Anything” session in January 2018, he had only nine months remaining to convince the people... View Details
By the time Dan Doctoroff, CEO of Sidewalk Labs, began hosting a Reddit “Ask Me Anything” session in January 2018, he had only nine months remaining to convince the people... View Details
Keywords:
Public Entrepreneurship;
Govtech;
CivicTech;
Smart Cities;
City Innovation;
Government Innovation;
Privacy;
Sidewalk Labs;
Dan Doctoroff;
Entrepreneurship;
Public Sector;
Consumer Behavior;
Governance;
Business and Government Relations;
Innovation and Invention;
Technology Industry;
Public Administration Industry;
Transportation Industry;
Real Estate Industry;
Canada
John, Leslie K., Mitchell Weiss, and Julia Kelley. "Sidewalk Labs: Privacy in a City Built from the Internet Up." Harvard Business School Case 819-024, October 2018. (Revised July 2019.) (Email mking@hbs.edu for a courtesy copy.)
- September 2018 (Revised May 2021)
- Teaching Plan
Eastern Bank: Innovating Through Eastern Labs
By: Karen Mills, Dennis Campbell and Aaron Mukerjee
Eastern Bank is a 200-year-old New England mutual bank with a community focus. Eastern specializes in small business lending, having made strategic investments to become the top SBA lender in New England in the midst of the Great Recession, when other banks were...
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Keywords:
Banks;
Fintech;
Innovation;
Innovation & Entrepreneurship;
Innovation And Strategy;
Technological Change;
Technology And Innovation Management;
Entrepreneurial Management;
Intrapreneurship;
Banks and Banking;
Innovation and Invention;
Entrepreneurship;
Innovation Strategy;
Technological Innovation;
Information Technology;
Management
- Article
Navigating Talent Hot Spots
By: William R. Kerr
Innovation clusters like San Francisco and Boston have long had an outsize impact on the global economy, and their influence keeps growing. In 2017, for instance, America’s ten largest tech hubs accounted for 58% of U.S. patents. Globally, cities such as Tokyo, Paris,...
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Keywords:
Talent and Talent Management;
Innovation and Invention;
Urban Scope;
Industry Clusters;
Innovation and Management
Kerr, William R. "Navigating Talent Hot Spots." Harvard Business Review 96, no. 5 (September–October 2018): 80–86.
- February 2018 (Revised March 2018)
- Case
Artificial Intelligence and the Machine Learning Revolution in Finance: Cogent Labs and the Google Cloud Platform (GCP)
By: Lauren Cohen, Christopher Malloy and William Powley
This case examines the intersection of two firms (Cogent Labs—a machine learning software firm in Tokyo; and Google, the technology infrastructure giant) attempting to exploit the benefits of artificial intelligence and machine learning in the financial services...
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Keywords:
Technological Innovation;
Finance;
Growth and Development Strategy;
Business Model;
Applications and Software;
Infrastructure;
Technology Industry;
Financial Services Industry
Cohen, Lauren, Christopher Malloy, and William Powley. "Artificial Intelligence and the Machine Learning Revolution in Finance: Cogent Labs and the Google Cloud Platform (GCP)." Harvard Business School Case 218-080, February 2018. (Revised March 2018.)
- October 2017 (Revised April 2019)
- Case
Eastern Bank: Innovating Through Eastern Labs
By: Karen Mills, Dennis Campbell and Aaron Mukerjee
Eastern Bank is a 200-year-old New England mutual bank with a community focus. Eastern specializes in small business lending, having made strategic investments to become the top SBA lender in New England in the midst of the Great Recession, when other banks were...
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Mills, Karen, Dennis Campbell, and Aaron Mukerjee. "Eastern Bank: Innovating Through Eastern Labs." Harvard Business School Case 318-068, October 2017. (Revised April 2019.)
- September 2014
- Case
Pfizer's Centers for Therapeutic Innovation (CTI)
By: Gary Pisano, James Weber and Kait Szydlowski
In 2010, Pfizer established four small research units in New York, Boston, San Francisco, and San Diego located close to several premier Academic Medical Centers (AMCs), or hospitals with adjoining medical schools. The goal of these units was to redesign collaboration...
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Keywords:
Drug Development;
Academic Collaboration;
Research And Development;
Innovation;
Translational Research;
Management;
Operations;
Problems and Challenges;
Research;
Science;
Information Technology;
Strategy;
Biotechnology Industry;
Pharmaceutical Industry;
North and Central America;
Europe;
Asia
Pisano, Gary, James Weber, and Kait Szydlowski. "Pfizer's Centers for Therapeutic Innovation (CTI)." Harvard Business School Case 615-024, September 2014.
- 2014
- Working Paper
The Organizational and Geographic Drivers of Absorptive Capacity: An Empirical Analysis of Pharmaceutical R&D Laboratories
By: Francesca Lazzeri and Gary P. Pisano
Scholars and practitioners alike now recognize that a firm's capacity to assimilate and use know-how from external sources—what Cohen and Levinthal (1990) called "absorptive capacity"—plays a central role in innovation performance. In recent years, a common strategy...
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Keywords:
Geographic Location;
Industry Clusters;
Knowledge Acquisition;
Pharmaceutical Industry;
San Francisco;
San Diego;
Massachusetts
Lazzeri, Francesca, and Gary P. Pisano. "The Organizational and Geographic Drivers of Absorptive Capacity: An Empirical Analysis of Pharmaceutical R&D Laboratories." Harvard Business School Working Paper, No. 14-098, April 2014.
- 2018
- Working Paper
Information Provision and Innovation: Natural Experiment of Herbal Patent Prior Art Adoption at the United States and European Patent Offices
By: Prithwiraj Choudhury and Tarun Khanna
We exploit a natural experiment to study how codifying information about prior innovation affects subsequent innovation. A codified database of traditional Indian herbal formulations was adopted by the European Patent Office (EPO) and the U.S. Patent and Trademark...
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Keywords:
Patents;
Plant-Based Agribusiness;
Ethnicity;
Health Care and Treatment;
Pharmaceutical Industry;
Agriculture and Agribusiness Industry;
China;
India
Choudhury, Prithwiraj, and Tarun Khanna. "Information Provision and Innovation: Natural Experiment of Herbal Patent Prior Art Adoption at the United States and European Patent Offices." Harvard Business School Working Paper, No. 14-079, February 2014. (Revised January 2018.)
- January 2014 (Revised December 2014)
- Case
GenapSys: Business Models for the Genome
By: Richard G. Hamermesh, Joseph B. Fuller and Matthew Preble
GenapSys, a California-based startup, was soon to release a new DNA sequencer that the company's founder, Hesaam Esfandyarpour, believed was truly revolutionary. The sequencer would be substantially less expensive—potentially costing just a few thousand dollars—and... View Details
Keywords:
DNA Sequencing;
Life Sciences;
Business Model;
Innovation & Entrepreneurship;
Health Care and Treatment;
Genetics;
Business Strategy;
Biotechnology Industry;
Pharmaceutical Industry;
Technology Industry;
Health Industry;
Medical Devices and Supplies Industry;
United States
Hamermesh, Richard G., Joseph B. Fuller, and Matthew Preble. "GenapSys: Business Models for the Genome." Harvard Business School Case 814-050, January 2014. (Revised December 2014.)
- October 2013 (Revised January 2014)
- Supplement
Fred Khosravi and AccessClosure (B)
By: Richard G. Hamermesh and Lauren Barley
It was January 2013, and Fred Khosravi, chairman of the board of AccessClosure Inc., wondered what the new year had in store for him and AccessClosure, the company he founded in late 2002. Khosravi was cautiously optimistic—the Mountain View, California-based medical...
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Keywords:
Medical Devices;
Vascular Closure Device;
Patent Litigation;
Patenting;
Biomedical Research;
Biotechnology;
Biotech;
Technological Innovation;
Patents;
Health Care and Treatment;
Biotechnology Industry;
United States;
California
Hamermesh, Richard G., and Lauren Barley. "Fred Khosravi and AccessClosure (B)." Harvard Business School Supplement 814-038, October 2013. (Revised January 2014.)
- Article
Experiments in Open Innovation at Harvard Medical School
By: Eva C. Guinan, Kevin J. Boudreau and Karim R. Lakhani
Harvard Medical School seems an unlikely organization to open up its innovation process. By most measures, the more than 20,000 faculty, research staff and graduate students affiliated with Harvard Medical School are already world class and at the top of the medical...
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Guinan, Eva C., Kevin J. Boudreau, and Karim R. Lakhani. "Experiments in Open Innovation at Harvard Medical School." Art. 3. MIT Sloan Management Review 54, no. 3 (Spring 2013): 45–52.
- 2013
- Case
Innovation and Development of China Machine Press in the New Century
By: F. Warren McFarlan, Ning Jia and Guo Jia
China Machine Press (CMP), founded in 1952, is a leading multi-field, multi-discipline and multimedia publishing group in China with large scale, comprehensive and specialized business that integrates paper media, audiovisual media and online media, and combines...
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McFarlan, F. Warren, Ning Jia, and Guo Jia. "Innovation and Development of China Machine Press in the New Century." Tsinghua University Case, 2013.
- 2013
- Teaching Note
Innovation and Development of China Machine Press in the New Century (TN)
By: F. Warren McFarlan, Ning Jia and Guo Jia
China Machine Press (CMP), founded in 1952, is a leading multi-field, multi-discipline and multimedia publishing group in China with large scale, comprehensive and specialized business that integrates paper media, audiovisual media and online media, and combines...
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McFarlan, F. Warren, Ning Jia, and Guo Jia. "Innovation and Development of China Machine Press in the New Century (TN)." Tsinghua University Teaching Note, 2013.
- April 2012 (Revised June 2012)
- Case
HP Labs in Singapore
By: Willy Shih, Pankaj Agarwal and Christine Chi
When HP established a branch of its corporate research lab in Singapore, the government played a key role through its Economic Development Board (EDB). Chris Whitney, the lab's director, sought to generate revenue from the lab's innovations, making it financially...
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Keywords:
Research and Development;
Factories, Labs, and Plants;
Development Economics;
Government and Politics;
Motivation and Incentives;
Innovation and Invention;
Revenue;
Technology Industry;
Singapore
Shih, Willy, Pankaj Agarwal, and Christine Chi. "HP Labs in Singapore." Harvard Business School Case 612-080, April 2012. (Revised June 2012.)
- Article
The Evolution of Science-Based Business: Innovating How We Innovate
By: Gary P. Pisano
Science has long been connected to innovation and to business. As early as the late 19th century, chemical companies, realizing the commercial potential of science, created the first industrial research laboratories. During much of the 20th century, large-scale...
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Keywords:
Entrepreneurship;
Governance;
Innovation and Management;
Risk Management;
Research and Development;
Science-Based Business;
Commercialization
Pisano, Gary P. "The Evolution of Science-Based Business: Innovating How We Innovate." Special Issue on Management Innovation—Essays in the Spirit of Alfred D. Chandler. Industrial and Corporate Change 19, no. 2 (April 2010): 465–482.
- January 2009
- Article
Spatial Diversity in Invention: Evidence from the Early R&D Labs
By: Tom Nicholas
This article uses historical data on inventor and firm R&D lab locations to examine the technological and geographic structure of corporate knowledge capital accumulation during a formative period in the organization of US innovation. Despite the localization of...
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Keywords:
Factories, Labs, and Plants;
Geographic Location;
Innovation and Invention;
Patents;
Knowledge Acquisition;
Research and Development;
United States
Nicholas, Tom. "Spatial Diversity in Invention: Evidence from the Early R&D Labs." Journal of Economic Geography 9, no. 1 (January 2009).
- June 2008 (Revised October 2009)
- Case
InnoCentive.com (A)
By: Karim R. Lakhani
InnoCentive.com, a firm connecting R&D labs of large organizations to diverse external solvers through innovation contests, has to decide if it will enable collaboration in its community. Case covers the basics of a distributed innovation system works and the...
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Keywords:
Collaborative Innovation and Invention;
Open Source Distribution;
Research and Development;
Competition;
Cooperation
Lakhani, Karim R. "InnoCentive.com (A)." Harvard Business School Case 608-170, June 2008. (Revised October 2009.)