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- All HBS Web (196)
- Faculty Publications (136)
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- All HBS Web (196)
- Faculty Publications (136)
- November 2019 (Revised June 2020)
- Case
Indigo Agriculture: Harnessing Nature
By: Marco Iansiti, Michael W. Toffel and James Barnett
Indigo Agriculture used a digital-enabled research and development (R&D) process to launch its initial product, microbial coatings for agricultural seeds, which increase crop yields while reducing the need for fertilizers. In doing so, the company developed direct...
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Keywords:
Carbon Sequestration;
Operations;
Supply Chain;
Social Enterprise;
Product Development;
Distribution Channels;
Business Strategy;
Digital Platforms;
Environmental Sustainability;
Science-Based Business;
Climate Change;
Agriculture and Agribusiness Industry;
Green Technology Industry;
United States;
Massachusetts
Iansiti, Marco, Michael W. Toffel, and James Barnett. "Indigo Agriculture: Harnessing Nature." Harvard Business School Case 620-024, November 2019. (Revised June 2020.)
- 17 Feb 2010
- First Look
First Look: Feb. 17
Working PapersThe Evolution of Science-Based Business: Innovating How We Innovate Author:Gary P. Pisano An abstract in unavailable at this time. Download the paper: http://www.hbs.edu/research/pdf/10-062.pdf PublicationsTargeted...
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Keywords:
Martha Lagace
- July 1997 (Revised June 2001)
- Case
H.E. Butt Grocery Company: A Leader in ECR Implementation (B) (Abridged)
By: Robert D. Austin and F. Warren McFarlan
H.E. Butt Grocery Co. led the grocery industry in adopting many innovations, including category management, electronic data interchange, and continuous replenishment. They have also moved aggressively and profitably into newer applications such as Scanner-based payment...
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Keywords:
Information Management;
Independent Innovation and Invention;
Innovation and Invention;
Business Organization;
Risk and Uncertainty;
Science-Based Business;
Cross-Cultural and Cross-Border Issues;
Management Analysis, Tools, and Techniques;
Risk Management;
Electronics Industry;
Computer Industry
Austin, Robert D., and F. Warren McFarlan. "H.E. Butt Grocery Company: A Leader in ECR Implementation (B) (Abridged)." Harvard Business School Case 198-016, July 1997. (Revised June 2001.)
- July 2011 (Revised January 2013)
- Case
Digital Microscopy Is Making Me Crazy!
By: Willy Shih
For Carl Zeiss Microimaging, modular hardware and software enabled customers to tailor Zeiss's broad range of microscopy systems hardware and software to meet a wide range of needs from basic scientific research in the biological and medical sciences to clinical...
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Keywords:
Information Infrastructure;
Applications and Software;
Corporate Strategy;
Disruptive Innovation;
Science-Based Business;
Management Analysis, Tools, and Techniques;
Business Conglomerates;
Digital Platforms;
Opportunities;
Medical Devices and Supplies Industry;
Computer Industry
Shih, Willy. "Digital Microscopy Is Making Me Crazy!" Harvard Business School Case 612-002, July 2011. (Revised January 2013.)
- October 2019 (Revised November 2019)
- Case
C16 Biosciences: Lab-Grown Palm Oil
By: Jeffrey J. Bussgang and Olivia Hull
Synthetic biology start-up C16 Biosciences wants to solve a big problem: replace palm oil, a major contributor to deforestation and climate change, with a lab-grown substitute. CEO Shara Ticku has ambitious plans to supply her lab-grown palm oil to food manufacturers,...
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Keywords:
Science-Based Business;
Environmental Sustainability;
Social Entrepreneurship;
Product Development;
Product Positioning;
Venture Capital;
Strategy;
Decision Making;
Food and Beverage Industry;
Consumer Products Industry
Bussgang, Jeffrey J., and Olivia Hull. "C16 Biosciences: Lab-Grown Palm Oil." Harvard Business School Case 820-008, October 2019. (Revised November 2019.)
- 28 Feb 2019
- Cold Call Podcast
Pursuing Precision Medicine at Intermountain Healthcare
- January 2024
- Case
Fusion Industry Association: Igniting the Future of Clean Energy
Fusion energy is evolving from a scientific idea to a commercial possibility, drawing large investments and regulatory discussions; how should the FIA navigate this evolution?
The Fusion Industry Association (FIA) is at the forefront of transforming fusion... View Details
The Fusion Industry Association (FIA) is at the forefront of transforming fusion... View Details
Keywords:
Science-Based Business;
Engineering;
Venture Capital;
Entrepreneurship;
Government and Politics;
Government Legislation;
Industry Clusters;
Industry Growth;
Industry Structures;
Technological Innovation;
Energy Industry;
United States
Krieger, Joshua Lev, Jim Matheson, Kyle R. Myers, and Henry Tao. "Fusion Industry Association: Igniting the Future of Clean Energy." Harvard Business School Case 624-064, January 2024.
- 30 Nov 2018
- What Do You Think?
What’s the Best Administrative Approach to Climate Change?
Summing Up: Should a 'Montreal Protocol' for Administering Global Warming Be Pursued? Climate change and how to manage it is a daunting subject. Nevertheless, several readers of this month’s column were willing to venture a model or two for administering a system...
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- September 1993 (Revised October 1994)
- Case
Environment and International Trade
During the 1990s, environmental activists became interested in trade issues for the first time. Whereas GATT, the General Agreement on Tariffs and Trade, had previously been the province of trade specialists, a new poster popular among environmentalists depicted the...
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Keywords:
Trade;
Environmental Sustainability;
Science-Based Business;
Policy;
Government and Politics;
Agreements and Arrangements;
Alliances;
Globalization;
International Relations;
Conflict of Interests
Reinhardt, Forest L. "Environment and International Trade." Harvard Business School Case 794-018, September 1993. (Revised October 1994.)
- September 2023 (Revised March 2024)
- Case
ReMo Energy: Sizing Up Investors
By: Jeffrey J. Bussgang and Tom Quinn
In 2023, executives with ReMo Energy (founded 2020) were deciding which size ammonia plant to build as their first project. Their innovative model produced ammonia—useful for making fertilizer and for energy storage—from renewable energy, and they had received funding...
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Keywords:
Factories, Labs, and Plants;
Business Startups;
Cost vs Benefits;
Design;
Energy Conservation;
Energy Generation;
Renewable Energy;
Venture Capital;
Investment Return;
Goods and Commodities;
Size;
Infrastructure;
Risk and Uncertainty;
Science-Based Business;
Commercialization;
Technological Innovation;
Chemical Industry;
Energy Industry;
Green Technology Industry;
United States;
Boston
Bussgang, Jeffrey J., and Tom Quinn. "ReMo Energy: Sizing Up Investors." Harvard Business School Case 824-027, September 2023. (Revised March 2024.)
- October 2019 (Revised December 2019)
- Supplement
Extend Fertility: Conceiving the Market for Egg Preservation (B)
By: Debora L. Spar and Olivia Hull
Keywords:
Strategy;
Information Technology;
Business Startups;
Entrepreneurship;
Innovation Strategy;
Technological Innovation;
Commercialization;
Science-Based Business;
Marketing Strategy;
Business Plan;
Product Marketing;
Product Launch;
Product Positioning;
Mission and Purpose;
Personal Development and Career;
Social Issues;
Integration;
Health;
Health Industry
Spar, Debora L., and Olivia Hull. "Extend Fertility: Conceiving the Market for Egg Preservation (B)." Harvard Business School Supplement 720-017, October 2019. (Revised December 2019.)
- 2008
- Chapter
The Evidence Does Not Speak for Itself: Expert Witnesses and the Organization of DNA-Typing Companies
By: Arthur A. Daemmrich
During the past 15 years, new biotechnology companies have promoted DNA typing as a sophisticated criminal and paternity identification technique. Private testing laboratories produce results that link individuals with crime scenes and fathers to their children....
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- 19 Jun 2017
- News
Can Neuroscience Find You the Perfect Job?
And they're, in our minds and in other people's minds as well, very good investors, specifically when it comes to science-based companies. And so really this was, to my mind, kind of the be all and end all. I just really admired a lot of...
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- July 2013 (Revised November 2021)
- Module Note
Exploration vs. Exploitation
By: Willy Shih
This module note introduces James March's concept of exploration and exploitation, and the management challenge of balancing the allocation of resources to the two activities in the firm. The note also touches on the O'Reilly and Tushman paper on the ambidextrous...
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Keywords:
Exploration And Exploitation;
Exploitation;
Research;
Scientific Research;
Product Commercialization;
Innovation and Invention;
Innovation and Management;
Innovation Leadership;
Innovation Strategy;
Technological Innovation;
Knowledge Acquisition;
Growth and Development Strategy;
Resource Allocation;
Strategic Planning;
Research and Development;
Science-Based Business;
Corporate Strategy;
Knowledge Sharing;
Biotechnology Industry;
Information Technology Industry;
Manufacturing Industry;
Medical Devices and Supplies Industry;
Pharmaceutical Industry;
Semiconductor Industry;
Technology Industry;
United States
Shih, Willy. "Exploration vs. Exploitation." Harvard Business School Module Note 614-004, July 2013. (Revised November 2021.)
- February 2014
- Case
BGI: Data-driven Research
By: Willy Shih and Sen Chai
BGI has the largest installed gene-sequencing capacity in the world, and to Zhang Gengyun, general manager of the Life Sciences Division, this represented an opportunity to apply his training as a plant breeder and his early career work as a biochemist to improving...
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Keywords:
Genomics;
Gene Sequencing;
Life Sciences;
Plant Breeding;
Human Genome Program;
Beijing Genomics Institute;
BGI;
Rice Genome;
Technological Innovation;
Innovation Strategy;
Research;
Research and Development;
Science;
Genetics;
Science-Based Business;
Strategy;
Commercialization;
Corporate Strategy;
Information Technology;
Applications and Software;
Agriculture and Agribusiness Industry;
Biotechnology Industry;
Food and Beverage Industry;
China;
United States
Shih, Willy, and Sen Chai. "BGI: Data-driven Research." Harvard Business School Case 614-056, February 2014.
- 12 Oct 2006
- First Look
First Look: October 12, 2006
prescriptions for companies, investors, and policymakers seeking ways to improve the industry's performance. According to Pisano, the biotech industry's problems stem from its special character as a science-based business. This character...
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Keywords:
Sean Silverthorne
- Research Summary
Overview
By: Kyle R. Myers
Professor Myers studies the economics of what determines the rate and direction of innovation. He has examined the reallocation of scientists through the use of targeted research grants at the National Institutes of Health, and is working to further understand how...
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Keywords:
Technology Networks;
Commercialization;
Science-Based Business;
Research and Development;
Knowledge Management;
Patents;
Innovation Strategy;
Technological Innovation;
Health Care and Treatment;
Entrepreneurship;
Health;
Innovation and Invention;
Science;
Technology;
Knowledge;
Intellectual Property;
Economics;
Microeconomics;
Biotechnology Industry;
Health Industry;
Pharmaceutical Industry;
Technology Industry
- August 1991 (Revised March 1993)
- Case
Champion International Corp.: Timber, Trade, and the Northern Spotted Owl
Champion's forest products division owns timberlands, sawmills, and plywood mills in the Pacific Northwest. The listing of the northern spotted owl as an endangered species, and restrictions on exports of logs from state-owned lands, have disrupted the stumpage, log...
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Keywords:
Science-Based Business;
Natural Environment;
Product Marketing;
Governing Rules, Regulations, and Reforms;
Government and Politics;
Environmental Sustainability;
Corporate Strategy;
Trade;
Decisions;
Management Teams;
Forest Products Industry;
North and Central America
Reinhardt, Forest L. "Champion International Corp.: Timber, Trade, and the Northern Spotted Owl." Harvard Business School Case 792-017, August 1991. (Revised March 1993.)
- August 2023 (Revised March 2024)
- Case
Arla Foods: Data-Driven Decarbonization (A)
By: Michael Parzen, Michael W. Toffel, Susan Pinckney and Amram Migdal
The case describes Arla’s history, in particular its climate change mitigation efforts, and how it implemented a price incentive system to motivate individual farms to implement scope 1 greenhouse gas emissions mitigation measures and receive a higher milk price. The...
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Keywords:
Dairy Industry;
Business Earnings;
Agribusiness;
Animal-Based Agribusiness;
Acquisition;
Mergers and Acquisitions;
Decision Making;
Decisions;
Voting;
Environmental Management;
Climate Change;
Environmental Regulation;
Environmental Sustainability;
Green Technology;
Pollution;
Moral Sensibility;
Values and Beliefs;
Financial Strategy;
Price;
Profit;
Revenue;
Food;
Geopolitical Units;
Global Strategy;
Ownership Type;
Cooperative Ownership;
Performance Efficiency;
Performance Evaluation;
Problems and Challenges;
Natural Environment;
Science-Based Business;
Business Strategy;
Commercialization;
Cooperation;
Corporate Strategy;
Food and Beverage Industry;
Agriculture and Agribusiness Industry;
Europe;
United Kingdom;
European Union;
Germany;
Denmark;
Sweden;
Luxembourg;
Belgium
Parzen, Michael, Michael W. Toffel, Susan Pinckney, and Amram Migdal. "Arla Foods: Data-Driven Decarbonization (A)." Harvard Business School Case 624-003, August 2023. (Revised March 2024.)
- November 2012
- Case
CSIRO: The Light Metals Flagship Decision
By: Willy Shih, Margaret P. Pierson and Dawn Lau
This case explores the challenge of investing in basic research as a public good. CSIRO was Australia's leading science and research agency, and it was chartered to enhance national prosperity through R&D. Its Flagships program was designed to align research interests...
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Keywords:
R&D;
Basic Research;
Government-funded Research;
Public Goods;
Extractive Industries;
Metals;
Metals Processing;
Decision Choices and Conditions;
Decisions;
Globalized Markets and Industries;
Growth and Development;
Innovation Strategy;
Technological Innovation;
Research and Development;
Science-Based Business;
Technology Adoption;
Technology Platform;
Manufacturing Industry;
Mining Industry;
Oceania;
Australia
Shih, Willy, Margaret P. Pierson, and Dawn Lau. "CSIRO: The Light Metals Flagship Decision." Harvard Business School Case 613-029, November 2012.