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      • Faculty Publications  (59)

      Scientific Research Remove Scientific Research →

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      • May 2022
      • Article

      How Status of Research Papers Affects the Way They Are Read and Cited

      By: Misha Teplitskiy, Eamon Duede, Michael Menietti and Karim R. Lakhani
      Although citations are widely used to measure the influence of scientific works, research shows that many citations serve rhetorical functions and reflect little-to-no influence on the citing authors. If highly cited papers disproportionately attract rhetorical...  View Details
      Keywords: Metrics; Influence; Status; Citations; Science; Measurement and Metrics; Research; Perception
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      Teplitskiy, Misha, Eamon Duede, Michael Menietti, and Karim R. Lakhani. "How Status of Research Papers Affects the Way They Are Read and Cited." Research Policy 51, no. 4 (May 2022).
      • April 27, 2022
      • Article

      Inequality in Researchers' Minds: Four Guiding Questions for Studying Subjective Perceptions of Economic Inequality

      By: Jon M. Jachimowicz, Shai Davidai, Daniela Goya-Tocchetto, Barnabas Szaszi, Martin Day, Stephanie Tepper, L. Taylor Phillips, M. Usman Mirza, Nailya Ordabayeva and Oliver P. Hauser
      Subjective perceptions of inequality can substantially influence policy attitudes, public health metrics, and societal well-being, but the lack of consensus in the scientific community on how to best operationalize and measure these perceptions may impede progress on...  View Details
      Keywords: Equality and Inequality; Perception; Analysis
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      Jachimowicz, Jon M., Shai Davidai, Daniela Goya-Tocchetto, Barnabas Szaszi, Martin Day, Stephanie Tepper, L. Taylor Phillips, M. Usman Mirza, Nailya Ordabayeva, and Oliver P. Hauser. "Inequality in Researchers' Minds: Four Guiding Questions for Studying Subjective Perceptions of Economic Inequality." Journal of Economic Surveys (April 27, 2022).
      • Article

      Potentially Long-Lasting Effects of the Pandemic on Scientists

      By: Jian Gao, Yian Yin, Kyle R. Myers, Karim R. Lakhani and Dashun Wang
      Two surveys of principal investigators conducted between April 2020 and January 2021 reveal that while the COVID-19 pandemic’s initial impacts on scientists’ research time seem alleviated, there has been a decline in the rate of initiating new projects. This dimension...  View Details
      Keywords: COVID-19; Scientists; Scientific Research; Health Pandemics; Research; Gender
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      Gao, Jian, Yian Yin, Kyle R. Myers, Karim R. Lakhani, and Dashun Wang. "Potentially Long-Lasting Effects of the Pandemic on Scientists." Art. 6188. Nature Communications 12 (2021).
      • May 2021
      • Case

      The SMA Foundation: Steering Therapeutic Research and Development in a Rare Disease

      By: Amitabh Chandra, Spencer Lee-Rey and Caroline Marra
      This case explores incentives for rare disease drug development by chronicling the role of the Spinal Muscular Atrophy (SMA) Foundation in forming strategic partnerships with the scientific research community and pharmaceutical developers to transform the trajectory...  View Details
      Keywords: Innovation and Invention; Strategy; Business or Company Management; Society; Health; Public Administration Industry; Health Industry; United States
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      Chandra, Amitabh, Spencer Lee-Rey, and Caroline Marra. "The SMA Foundation: Steering Therapeutic Research and Development in a Rare Disease." Harvard Business School Case 621-112, May 2021.
      • February 2021 (Revised January 2022)
      • Case

      Marie Curie: Changing the World

      By: Robert Simons and Shirley Sun
      This case describes the rise of Marie Curie from a poor family in Poland to the pinnacle of scientific fame. The case describes how Curie, as a young woman interested in science, found a way to earn a doctorate at the Sorbonne and perform pathbreaking research on...  View Details
      Keywords: Science; Research; Personal Characteristics; Mission and Purpose; Success; Work-Life Balance; Higher Education; Personal Development and Career
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      Simons, Robert, and Shirley Sun. "Marie Curie: Changing the World." Harvard Business School Case 121-059, February 2021. (Revised January 2022.)
      • Article

      Assessing the Food and Drug Administration's Risk-Based Framework for Software Precertification with Top Health Apps in the United States: Quality Improvement Study

      By: Noy Alon, Ariel Dora Stern and John Torous
      BACKGROUND: As the development of mobile health apps continues to accelerate, the need to implement a framework that can standardize categorizing these apps to allow for efficient, yet robust regulation grows. However, regulators and researchers are faced with numerous...  View Details
      Keywords: Mobile Health; Smartphone; Food And Drug Administration; Risk-based Framework; Health Care and Treatment; Mobile Technology; Software; Framework
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      Alon, Noy, Ariel Dora Stern, and John Torous. "Assessing the Food and Drug Administration's Risk-Based Framework for Software Precertification with Top Health Apps in the United States: Quality Improvement Study." JMIR mHealth and uHealth 8, no. 10 (October 2020).
      • 2020
      • Working Paper

      When Do Experts Listen to Other Experts? The Role of Negative Information in Expert Evaluations for Novel Projects

      By: Jacqueline N. Lane, Misha Teplitskiy, Gary Gray, Hardeep Ranu, Michael Menietti, Eva C. Guinan and Karim R. Lakhani
      The evaluation of novel projects lies at the heart of scientific and technological innovation, and yet literature suggests that this process is subject to inconsistency and potential biases. This paper investigates the role of information sharing among experts as the...  View Details
      Keywords: Project Evaluation; Innovation; Knowledge Frontier; Negativity Bias; Projects; Innovation and Invention; Information; Diversity; Judgments
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      Lane, Jacqueline N., Misha Teplitskiy, Gary Gray, Hardeep Ranu, Michael Menietti, Eva C. Guinan, and Karim R. Lakhani. "When Do Experts Listen to Other Experts? The Role of Negative Information in Expert Evaluations for Novel Projects." Harvard Business School Working Paper, No. 21-007, July 2020. (Revised November 2020.)
      • 2020
      • Working Paper

      Scientific Production: An Exploration into Organization, Resource Allocation, and Funding

      By: Jerry Thursby, Marie Thursby, Karim R. Lakhani, Kyle R. Myers, Nina Cohodes, Sarah Bratt, Dennis Byrski, Hannah Cohoon and Maria Roche
      Production of scientific knowledge is core to civilizational advancement in economic and material wellbeing of societies. Despite its fundamental importance, however, a systematic effort to quantitatively study the factors underlying scientific production, particularly...  View Details
      Keywords: Funding; Science; Knowledge; Research; Information Management; Resource Allocation
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      Thursby, Jerry, Marie Thursby, Karim R. Lakhani, Kyle R. Myers, Nina Cohodes, Sarah Bratt, Dennis Byrski, Hannah Cohoon, and Maria Roche. "Scientific Production: An Exploration into Organization, Resource Allocation, and Funding." Working Paper, May 2020.
      • March 2020
      • Case

      ZEISS Group: Organize by Customer Culture?

      By: Willy C. Shih
      How should ZEISS, the German manufacturer of precision optical and optoelectronic systems manage two historic businesses that operated fairly autonomously? The Industrial Quality Solutions (IQS) business sold measurement equipment to manufacturing companies in sectors...  View Details
      Keywords: Organizational Structure; Organizational Culture; Manufacturing Industry; Europe; Germany
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      Shih, Willy C. "ZEISS Group: Organize by Customer Culture?" Harvard Business School Case 620-103, March 2020.
      • July 2019
      • Article

      'Forward Flow': A New Measure to Quantify Free Thought and Predict Creativity

      By: Kurt Gray, Stephen Anderson, Eric Evan Chen, John Michael Kelly, Michael S. Christian, John Patrick, Laura Huang, Yoed N. Kenett and Kevin Lewis
      When the human mind is free to roam, its subjective experience is characterized by a continuously evolving stream of thought. Although there is a technique that captures people’s streams of free thought—free association—its utility for scientific research is undermined...  View Details
      Keywords: Cognition and Thinking; Creativity; Forecasting and Prediction
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      Gray, Kurt, Stephen Anderson, Eric Evan Chen, John Michael Kelly, Michael S. Christian, John Patrick, Laura Huang, Yoed N. Kenett, and Kevin Lewis. "'Forward Flow': A New Measure to Quantify Free Thought and Predict Creativity." American Psychologist 74, no. 5 (July 2019): 539–554.
      • 2018
      • Chapter

      Competing Interests

      By: Joel Goh
      Book Abstract: The editors, aided by a team of internationally acclaimed experts, have curated this timely volume to help newcomers and seasoned researchers alike to rapidly comprehend a diverse set of thrusts and tools in this rapidly growing cross-disciplinary field....  View Details
      Keywords: Healthcare; Analytics; Health Care and Treatment; Research; Competition
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      Goh, Joel. "Competing Interests." Chap. 4 in Handbook of Healthcare Analytics: Theoretical Minimum for Conducting 21st Century Research on Healthcare Operations, edited by Tinglong Dai and Sridhar Tayur, 51–78. John Wiley & Sons, 2018.
      • Article

      A Field Experiment on Search Costs and the Formation of Scientific Collaborations

      By: Kevin Boudreau, Tom Brady, Ina Ganguli, Patrick Gaule, Eva C. Guinan, Anthony Hollenberg and Karim R. Lakhani
      We present the results of a field experiment conducted at Harvard Medical School to understand the extent to which search costs affect matching among scientific collaborators. We generated exogenous variation in search costs for pairs of potential collaborators by...  View Details
      Keywords: Search Costs; Cost; Marketplace Matching; Groups and Teams; Science; Collaborative Innovation and Invention
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      Boudreau, Kevin, Tom Brady, Ina Ganguli, Patrick Gaule, Eva C. Guinan, Anthony Hollenberg, and Karim R. Lakhani. "A Field Experiment on Search Costs and the Formation of Scientific Collaborations." Review of Economics and Statistics 99, no. 4 (October 2017): 565–576.
      • September 2017
      • Case

      Sensing (and Monetizing) Happiness at Hitachi

      By: Ethan Bernstein and Stephanie Marton
      Inspired by research linking happiness and productivity, Hitachi had invested in developing new “people analytics” technologies to help companies increase employee happiness. Hitachi had begun manufacturing high-tech badges that quantify a wearer’s activity patterns....  View Details
      Keywords: People Analytics; Japan; Sociometers; Wearables; Interpersonal Communication; Human Resources; Happiness; Technology Industry; Japan
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      Bernstein, Ethan, and Stephanie Marton. "Sensing (and Monetizing) Happiness at Hitachi." Harvard Business School Case 418-019, September 2017.
      • 2017
      • Article

      True Happiness: The Role of Morality in the Concept of Happiness

      By: Jonathan Phillips, Julian De Freitas, Christian Mott, June Gruber and Joshua Knobe
      Recent scientific research has settled on a purely descriptive definition of happiness that is focused solely on agents' psychological states (high positive affect, low negative affect, high life satisfaction). In contrast to this understanding, recent research has...  View Details
      Keywords: Moral Cognition; Happiness; Moral Sensibility; Emotions; Well-being
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      Phillips, Jonathan, Julian De Freitas, Christian Mott, June Gruber, and Joshua Knobe. "True Happiness: The Role of Morality in the Concept of Happiness." Journal of Experimental Psychology: General 146, no. 2 (2017): 165–181.
      • Winter 2017
      • Article

      Why Big Data Isn't Enough

      By: Sen Chai and Willy C. Shih
      There is a growing belief that sophisticated algorithms can explore huge databases and find relationships independent of any preconceived hypotheses. But in businesses that involve scientific research and technological innovation, this approach is misguided and...  View Details
      Keywords: Big Data; Science-based; Science; Scientific Research; Data Analytics; Data Science; Data-driven Management; Data Scientists; Technological Innovation; Data and Data Sets; Mathematical Methods; Theory
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      Chai, Sen, and Willy C. Shih. "Why Big Data Isn't Enough." Art. 58227. MIT Sloan Management Review 58, no. 2 (Winter 2017): 57–61.
      • Article

      One Obstacle to Curing Cancer: Patient Data Isn't Shared

      By: Richard G. Hamermesh and Kathy Giusti
      Precision Medicine requires large datasets to identify the mutations that lead to various cancers. Currently, genomic information is hoarded in fragmented silos within numerous academic medical centers, pharmaceutical companies, and some disease-based foundations. For...  View Details
      Keywords: Healthcare; Technological And Scientific Innovation; Cancer Care In The U.S.; Cancer Treatment; Precision Medicine; Personalized Medicine; Data Sharing; Technological Innovation; Data and Data Sets; Health Disorders; Medical Specialties; Research and Development; Customization and Personalization; Health Industry; United States
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      Hamermesh, Richard G., and Kathy Giusti. "One Obstacle to Curing Cancer: Patient Data Isn't Shared." Harvard Business Review (website) (November 28, 2016).
      • October 2016 (Revised September 2017)
      • Case

      The CRISPR-Cas9 Quarrel

      By: Richard G. Hamermesh and Matthew G. Preble
      In mid-2016, the Broad Institute and the University of California, Berkeley were in the middle of a contentious patent dispute over which entity controlled a breakthrough gene editing technology called CRISPR-Cas9. With CRISPR-Cas9, scientists might soon be able to...  View Details
      Keywords: CRISPR; Broad Institute; University Of California Berkeley; Intellectual Property; Patents; Law; Lawsuits and Litigation; Science; Genetics; Entrepreneurship; Biotechnology Industry; United States
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      Hamermesh, Richard G., and Matthew G. Preble. "The CRISPR-Cas9 Quarrel." Harvard Business School Case 817-020, October 2016. (Revised September 2017.)
      • October 2016
      • Article

      Looking Across and Looking Beyond the Knowledge Frontier: Intellectual Distance and Resource Allocation in Science

      By: Kevin J. Boudreau, Eva Guinan, Karim R. Lakhani and Christoph Riedl
      Selecting among alternative innovative projects is a core management task in all innovating organizations. In this paper, we focus on the evaluation of frontier scientific research projects. We argue that the "intellectual distance" between the knowledge embodied in...  View Details
      Keywords: Knowledge; Innovation; Novelty; Evaluation; Resource Allocation; Decision Choices and Conditions; Innovation and Management; Science-Based Business; Experience and Expertise
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      Boudreau, Kevin J., Eva Guinan, Karim R. Lakhani, and Christoph Riedl. "Looking Across and Looking Beyond the Knowledge Frontier: Intellectual Distance and Resource Allocation in Science." Management Science 62, no. 10 (October 2016).
      • February 2016
      • Article

      Bridging Science and Technology Through Academic-Industry Partnerships

      By: Sen Chai and Willy C. Shih
      Partnerships that foster the translation of scientific advances emerging from academic research organizations into commercialized products at private firms are a policy tool that has attracted increased interest. This paper examines empirical data from the Danish...  View Details
      Keywords: Economic Development; Technological Change; Government Policy; Technological Innovation; Research and Development; Technology; Policy; Technology Industry; Denmark
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      Chai, Sen, and Willy C. Shih. "Bridging Science and Technology Through Academic-Industry Partnerships." Research Policy 45, no. 1 (February 2016): 148–158.
      • November 2014
      • Case

      Napalm: From Soldiers Field to Trang Bang

      By: Tom Nicholas and Jonas Peter Akins
      Napalm is one of the most destructive weapons ever to be invented. Yet, at its original inception it was nothing more than a technical challenge, and it was never intended to be used in indiscriminate antipersonnel warfare. The pathway of its development by a Harvard...  View Details
      Keywords: Moral Sensibility; War; Chemicals; Research and Development; Chemical Industry; Viet Nam; Cambridge; United States
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      Nicholas, Tom, and Jonas Peter Akins. "Napalm: From Soldiers Field to Trang Bang." Harvard Business School Case 815-060, November 2014.
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