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- 2021
- Working Paper
Fecal Microbiota Transplants (FMT): Case Histories of Significant Medical Advances
By: Amar Bhide and Srikant M. Datar
By 2013, after many decades of very slow development and adoption, Fecal Microbiota Transplantation procedures were attracting widespread attention. This case history chronicles the: 1) pioneering fecal transplants performed in the 20th century; 2) development of the...
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Keywords:
Health Care and Treatment;
Innovation and Invention;
Governing Rules, Regulations, and Reforms
Bhide, Amar, and Srikant M. Datar. "Fecal Microbiota Transplants (FMT): Case Histories of Significant Medical Advances." Harvard Business School Working Paper, No. 21-132, June 2021.
- March 2021 (Revised April 2021)
- Technical Note
Tales of Life-changing Innovations: Too Simple to be Safe? | Note on the Development of Fecal Transplants
By: Amar Bhidé and Srikant M. Datar
Bhidé, Amar, and Srikant M. Datar. "Tales of Life-changing Innovations: Too Simple to be Safe? | Note on the Development of Fecal Transplants." Harvard Business School Technical Note 321-065, March 2021. (Revised April 2021.)
- December 2020 (Revised May 2021)
- Case
Dame Cicely Saunders and the Modern Hospice Movement: A Brother's View
By: Amar Bhidé and Srikant M. Datar
Bhidé, Amar, and Srikant M. Datar. "Dame Cicely Saunders and the Modern Hospice Movement: A Brother's View." Harvard Business School Case 321-102, December 2020. (Revised May 2021.)
- December 2020 (Revised May 2021)
- Background Note
Tales of Life-changing Innovations: Living Drugs | Note on the Development of CAR-T Therapies (through 2019)
By: Amar Bhidé and Srikant M. Datar
Bhidé, Amar, and Srikant M. Datar. "Tales of Life-changing Innovations: Living Drugs | Note on the Development of CAR-T Therapies (through 2019)." Harvard Business School Background Note 321-063, December 2020. (Revised May 2021.)
- 2021
- Working Paper
Development of CAR-T Therapies: Case Histories of Significant Medical Advances
By: Amar Bhidé and Srikant M. Datar
In 2017, the US Food and Drug Administration (FDA) approved an immunotherapeutic treatment, called CAR-T therapy, for two kinds of blood cancers—acute leukemia (ALL) and a lymphoma. We describe 1) how CAR-T works; 2) the foundational advances and discoveries; 3)...
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Keywords:
Immunotherapy;
Health Care and Treatment;
Innovation and Invention;
Research and Development;
Governing Rules, Regulations, and Reforms
Bhidé, Amar, and Srikant M. Datar. "Development of CAR-T Therapies: Case Histories of Significant Medical Advances." Harvard Business School Working Paper, No. 21-035, August 2020. (Revised May 2021.)
- 2021
- Working Paper
Cephalosporins: Case Histories of Significant Medical Advances
By: Amar Bhidé, Srikant Datar and Katherine Stebbins
Our case history describes the development of three generations of cephalosporins—antibiotics that have significantly reduced hospital infections. After providing an overview of antibiotic development and its challenges we describe how: 1) Early (pre-cephalosporin)...
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Keywords:
Health Care and Treatment;
Technological Innovation;
Innovation Strategy;
Technology Adoption;
Collaborative Innovation and Invention;
Innovation and Invention;
Governing Rules, Regulations, and Reforms
Bhidé, Amar, Srikant Datar, and Katherine Stebbins. "Cephalosporins: Case Histories of Significant Medical Advances." Harvard Business School Working Paper, No. 20-133, July 2020. (Revised May 2021.)
- 2021
- Working Paper
Laparoscopy: Case Histories of Significant Medical Advances
By: Amar Bhidé, Caitlin N. Bowler and Srikant M. Datar
We describe how operations through laparoscopes—tubular instruments inserted into abdominal cavities—revolutionized gynecological and other surgeries inside the abdomen such as gall bladder removal. Specifically, we chronicle the: 1) foundational technologies and...
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Keywords:
Health Care and Treatment;
Technological Innovation;
Innovation Strategy;
Technology Adoption;
Collaborative Innovation and Invention;
Innovation and Invention;
Governing Rules, Regulations, and Reforms
Bhidé, Amar, Caitlin N. Bowler, and Srikant M. Datar. "Laparoscopy: Case Histories of Significant Medical Advances." Harvard Business School Working Paper, No. 20-008, July 2019. (Revised May 2021.)
- 2021
- Working Paper
Magnetic Resonance Imaging: Case Histories of Significant Medical Advances
By: Srikant M. Datar, Amar Bhidé and Katherine Stebbins
We describe how and why Magnetic Resource Imaging (MRI) came to complement – and partially replace -- computed tomography (CT) imaging of soft tissue. Specifically we chronicle: 1) the development of foundational techniques and prototypes (through the 1970s); 2)...
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Keywords:
Health Care and Treatment;
Technological Innovation;
Innovation Strategy;
Technology Adoption;
Collaborative Innovation and Invention;
Innovation and Invention;
Governing Rules, Regulations, and Reforms
Datar, Srikant M., Amar Bhidé, and Katherine Stebbins. "Magnetic Resonance Imaging: Case Histories of Significant Medical Advances." Harvard Business School Working Paper, No. 20-001, July 2019. (Revised June 2021.)
- October 1990 (Revised August 1991)
- Case
Peanut Butter Fantasies
By: Amar Bhide and Myra M. Hart
Addresses the interrelated challenges of marketing and finance faced by a small, struggling packaged foods company.
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Keywords:
Business Ventures;
Finance;
Business or Company Management;
Marketing;
Distribution;
Problems and Challenges;
Food and Beverage Industry
Bhide, Amar, and Myra M. Hart. "Peanut Butter Fantasies." Harvard Business School Case 391-072, October 1990. (Revised August 1991.)
- July 1990
- Background Note
Note on Acquiring Bank Credit
By: Amar Bhide and Howard H. Stevenson
Outlines the issues and alternatives faced by start-up businesses in attracting bank credit. The topics covered are how to lay the groundwork for establishing a banking relationship, selecting a bank, preparing an application, and negotiating a loan.
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Bhide, Amar, and Howard H. Stevenson. "Note on Acquiring Bank Credit." Harvard Business School Background Note 391-010, July 1990.