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- December 2023 (Revised February 2024)
- Case
Transforming Healthcare Delivery at Karolinska University Hospital
By: Susanna Gallani, Mary Witkowski, Elena Corsi and Nikolina Jonsson
The case study examines the journey toward value-based healthcare at Karolinska University Hospital. The hospital's ambitious shift to a patient-centered care delivery model, accompanied by the construction of a new facility, encountered challenges such as high costs,...
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Keywords:
Change Management;
Transformation;
Transition;
Business Organization;
Communication Strategy;
Information Infrastructure;
Service Delivery;
Organizational Change and Adaptation;
Organizational Structure;
Health Industry;
Sweden;
Europe
Gallani, Susanna, Mary Witkowski, Elena Corsi, and Nikolina Jonsson. "Transforming Healthcare Delivery at Karolinska University Hospital." Harvard Business School Case 124-070, December 2023. (Revised February 2024.)
- 2023
- Article
Dynamic HTA for Digital Health Solutions: Opportunities and Challenges for Patient-Centered Evaluation
By: Jan B. Brönneke, Annika Herr, Simon Reif and Ariel D. Stern
Germany’s 2019 Digital Healthcare Act (Digitale-Versorgung-Gesetz, or DVG) created a number of opportunities for the digital transformation of the health care delivery system. Key among these was the creation of a reimbursement pathway for patient-centered digital...
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Keywords:
Digital Transformation;
Applications and Software;
Product Development;
Insurance;
Policy;
Health Industry;
Germany
Brönneke, Jan B., Annika Herr, Simon Reif, and Ariel D. Stern. "Dynamic HTA for Digital Health Solutions: Opportunities and Challenges for Patient-Centered Evaluation." International Journal of Technology Assessment in Health Care 39, no. 1 (2023).
- October 2023 (Revised October 2023)
- Case
Veeva Systems: The Next Frontier
By: Satish Tadikonda and William Marks
Born out of a desire to bring technological advances in enterprise software into the healthcare vertical, Peter Gassner and Matt Wallach founded Veeva to bring life sciences companies into the digital age for data management in both the commercial and R&D sectors. Over...
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Tadikonda, Satish, and William Marks. "Veeva Systems: The Next Frontier." Harvard Business School Case 824-074, October 2023. (Revised October 2023.)
- August 2023
- Supplement
Parexel (B): The Future of the CRO Industry
By: Regina E. Herzlinger and Ben Creo
How should Parexel respond to the rapidly changing environment in clinical research, now that it is owned by a private equity firm and its founder is no longer with the firm?
Parexel, a major clinical research organization, has experienced substantial... View Details
Parexel, a major clinical research organization, has experienced substantial... View Details
- August 2023
- Article
Explaining Machine Learning Models with Interactive Natural Language Conversations Using TalkToModel
By: Dylan Slack, Satyapriya Krishna, Himabindu Lakkaraju and Sameer Singh
Practitioners increasingly use machine learning (ML) models, yet models have become more complex and harder to understand. To understand complex models, researchers have proposed techniques to explain model predictions. However, practitioners struggle to use...
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Slack, Dylan, Satyapriya Krishna, Himabindu Lakkaraju, and Sameer Singh. "Explaining Machine Learning Models with Interactive Natural Language Conversations Using TalkToModel." Nature Machine Intelligence 5, no. 8 (August 2023): 873–883.
- July 2023
- Case
DayTwo: Going to Market with Gut Microbiome (Abridged)
By: Ayelet Israeli
DayTwo is a young Israeli startup that applies research on the gut microbiome and machine learning algorithms to deliver personalized nutritional recommendations to its users in order to minimize blood sugar spikes after meals. After a first year of trial rollout in...
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Keywords:
Business Startups;
AI and Machine Learning;
Nutrition;
Market Entry and Exit;
Product Marketing;
Distribution Channels
Israeli, Ayelet. "DayTwo: Going to Market with Gut Microbiome (Abridged)." Harvard Business School Case 524-015, July 2023.
- July 2023
- Case
HealthVerity: Real World Data and Evidence
By: Satish Tadikonda
Andrew Kress (CEO and founder) and his team had built a promising marketplace business at HealthVerity serving its core market in healthcare, with a focus on pharmaceutical R&D and services. Thus far, HealthVerity’s products had been unique to the pharma and pharma...
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Tadikonda, Satish. "HealthVerity: Real World Data and Evidence." Harvard Business School Case 824-019, July 2023.
- June 2023
- Article
Gaining Organizational Adoption: Strategically Pacing the Deployment of Digital Innovations
By: Rebecca Karp
Scholars have long suggested that to foster adoption for their innovative products and services, entrepreneurs should engage with customers to better understand their unmet needs. Yet, customers frequently reside in organizations, and organizational members may not be...
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Keywords:
Entrepreneurship And Strategy;
Digital Innovation;
Healthcare;
Work And Organizations;
Organizational Adoption;
B2B;
Customers;
Technology Adoption;
Innovation Strategy;
Organizational Change and Adaptation
Karp, Rebecca. "Gaining Organizational Adoption: Strategically Pacing the Deployment of Digital Innovations." Academy of Management Journal 66, no. 3 (June 2023): 773–796.
- December 2022 (Revised June 2023)
- Case
Sword Health
By: Regina E. Herzlinger and Annelena Lobb
Virgilio “V” Bento, CEO of Sword Health—a startup that provided virtual physical therapy to patients in self-insured firms via AI and sensor technology with supervision by a physical therapist with a doctorate—considered how to increase its U.S. market share. To do so,...
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Keywords:
Business Growth and Maturation;
Competitive Strategy;
Technology Industry;
Technology Industry
Herzlinger, Regina E., and Annelena Lobb. "Sword Health." Harvard Business School Case 323-022, December 2022. (Revised June 2023.)
- November 2022
- Case
Ajax Health: A New Model for Medical Technology Innovation
By: Regina E. Herzlinger and Ben Creo
This case teaches key success factors for both startup and established MedTech firms. It examines how to structure a firm to maximize innovation and financial returns with organizational structures that better align the incentives for the different skill sets...
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Keywords:
Business Startups;
Success;
Innovation Strategy;
Mergers and Acquisitions;
Market Entry and Exit;
Financial Strategy;
Business Model;
Partners and Partnerships;
Entrepreneurship;
Private Equity;
Technology Industry;
Technology Industry
Herzlinger, Regina E., and Ben Creo. "Ajax Health: A New Model for Medical Technology Innovation." Harvard Business School Case 323-043, November 2022.
- November 2022
- Case
The Battle Among Channels for Marketing Pharmaceuticals: UpScript, Pharmacy Benefit Managers, and Direct-to-Consumer Sales
By: Regina E. Herzlinger and Tiffany Farrell
Can an online, direct-to-consumer pharmacy both improve the quality and speed of care for patients who need branded drugs and stabilize profits for pharmaceutical manufacturers? UpScript, after years spent achieving legal and regulatory compliance and simultaneous...
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Keywords:
DTC;
Internet and the Web;
Marketing Channels;
Customer Value and Value Chain;
Governing Rules, Regulations, and Reforms;
Competitive Strategy;
Service Delivery;
Growth and Development Strategy;
Pharmaceutical Industry;
Health Industry;
Retail Industry
Herzlinger, Regina E., and Tiffany Farrell. "The Battle Among Channels for Marketing Pharmaceuticals: UpScript, Pharmacy Benefit Managers, and Direct-to-Consumer Sales." Harvard Business School Case 323-031, November 2022.
- October 2022 (Revised May 2023)
- Case
Podimetrics: Next Steps for Diabetes Cases
By: Regina E. Herzlinger and Ben Creo
Podimetrics, a virtual care management company treating adults with acute diabetes, sat at the intersection of medical device technology, digital health, and health services. Its SmartMat had demonstrated that it could help prevent amputations and that people with...
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Keywords:
Health Care;
Health Care Delivery;
Health Care Entrepreneurship;
Health Care Outcomes;
Diabetes;
Chronic Disease;
Chronic Illness;
Health Care and Treatment;
Health Disorders;
Medical Specialties;
Technological Innovation;
Innovation Strategy;
Product Development;
Business Model;
Customer Focus and Relationships;
Medical Devices and Supplies Industry;
Health Industry
- September 2022
- Case
Proactive for Her
By: Rembrand Koning and Kairavi Dey
Proactive for Her began amid the COVID-19 pandemic, in August 2020 as a digital platform to provide accessible, evidence-based, primary, preventive non-judgmental healthcare services for Indian women, who were often dissuaded from seeking help as premarital sex and...
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Keywords:
Women's Health;
Healthcare;
India;
Start-up;
Telehealth;
Digital Platforms;
Health Care and Treatment;
Customer Focus and Relationships;
Business Startups;
Health Industry;
Asia;
South Asia;
India
Koning, Rembrand, and Kairavi Dey. "Proactive for Her." Harvard Business School Case 723-351, September 2022.
- 2022
- Article
Data Poisoning Attacks on Off-Policy Evaluation Methods
By: Elita Lobo, Harvineet Singh, Marek Petrik, Cynthia Rudin and Himabindu Lakkaraju
Off-policy Evaluation (OPE) methods are a crucial tool for evaluating policies in high-stakes domains such as healthcare, where exploration is often infeasible, unethical, or expensive. However, the extent to which such methods can be trusted under adversarial threats...
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Lobo, Elita, Harvineet Singh, Marek Petrik, Cynthia Rudin, and Himabindu Lakkaraju. "Data Poisoning Attacks on Off-Policy Evaluation Methods." Proceedings of the Conference on Uncertainty in Artificial Intelligence (UAI) 38th (2022): 1264–1274.
- 2022
- Article
Towards Robust Off-Policy Evaluation via Human Inputs
By: Harvineet Singh, Shalmali Joshi, Finale Doshi-Velez and Himabindu Lakkaraju
Off-policy Evaluation (OPE) methods are crucial tools for evaluating policies in high-stakes domains such as healthcare, where direct deployment is often infeasible, unethical, or expensive. When deployment environments are expected to undergo changes (that is, dataset...
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Singh, Harvineet, Shalmali Joshi, Finale Doshi-Velez, and Himabindu Lakkaraju. "Towards Robust Off-Policy Evaluation via Human Inputs." Proceedings of the AAAI/ACM Conference on Artificial Intelligence, Ethics, and Society (2022): 686–699.
- July 2022 (Revised February 2024)
- Teaching Note
The DivaCup: Navigating Distribution and Growth
By: Ayelet Israeli
Teaching Note for HBS Case No. 519-055. When the mother-daughter founders of DivaCup set out with a mission to disrupt the menstrual care industry with an innovative product form, they initially struggled to gain legitimacy and convince retailers to carry their unique...
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Keywords:
Female;
Female Ceo;
Female Entrepreneur;
Female Protagonist;
Health & Wellness;
Healthcare;
Price Policies;
Minimum Advertised Price;
Differentiation;
Positioning;
Growth;
Health;
Health Care and Treatment;
Price;
Disruption;
Distribution;
Distribution Channels;
Competitive Strategy;
Competition;
Growth Management;
Mission and Purpose;
Product Development;
Product Marketing;
Product Launch;
Product Positioning;
Advertising;
Business Startups;
Internet and the Web;
Entrepreneurship;
Social Entrepreneurship;
Social Issues;
Social Enterprise;
Green Technology Industry;
Green Technology Industry;
Green Technology Industry;
Green Technology Industry;
Green Technology Industry;
Green Technology Industry;
Green Technology Industry;
Green Technology Industry;
Canada;
United States;
United Kingdom
- 2022
- Conference Presentation
Towards the Unification and Robustness of Post hoc Explanation Methods
By: Sushant Agarwal, Shahin Jabbari, Chirag Agarwal, Sohini Upadhyay, Steven Wu and Himabindu Lakkaraju
As machine learning black boxes are increasingly being deployed in critical domains such as healthcare and criminal justice, there has been a growing emphasis on developing techniques for explaining these black boxes in a post hoc manner. In this work, we analyze two...
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Keywords:
AI and Machine Learning
Agarwal, Sushant, Shahin Jabbari, Chirag Agarwal, Sohini Upadhyay, Steven Wu, and Himabindu Lakkaraju. "Towards the Unification and Robustness of Post hoc Explanation Methods." Paper presented at the 3rd Symposium on Foundations of Responsible Computing (FORC), 2022.
- Article
Advancing Digital Health Applications: Priorities for Innovation in Real-World Evidence Generation
By: Ariel Dora Stern, Jan Brönneke, Jörg F Debatin, Julia Hagen, Henrik Matthies, Smit Patel, Ieuan Clay, Bjoern Eskofier, Annika Herr, Kurt Hoeller, Ashley Jaksa, Daniel B Kramer, Mattias Kyhlstedt, Katherine T Lofgren, Nirosha Mahendraratnam, Holger Muehlan, Simon Reif, Lars Riedemann and Jennifer C Goldsack
In 2019, Germany passed the Digital Healthcare Act, which, among other things, created a “Fast-Track” regulatory and reimbursement pathway for digital health applications in the German market. The pathway explicitly provides for flexibility in how researchers can...
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Stern, Ariel Dora, Jan Brönneke, Jörg F Debatin, Julia Hagen, Henrik Matthies, Smit Patel, Ieuan Clay, Bjoern Eskofier, Annika Herr, Kurt Hoeller, Ashley Jaksa, Daniel B Kramer, Mattias Kyhlstedt, Katherine T Lofgren, Nirosha Mahendraratnam, Holger Muehlan, Simon Reif, Lars Riedemann, and Jennifer C Goldsack. "Advancing Digital Health Applications: Priorities for Innovation in Real-World Evidence Generation." Lancet Digital Health 4, no. 3 (March 2022): e200–e206.
- February 2022
- Case
Cleveland Clinic Abu Dhabi
By: Linda A. Hill and Emily Tedards
In 2006, the Cleveland Clinic and Mubadala Investment Company partnered with a bold ambition to deliver world class healthcare in the United Arab Emirates. In 2015, after nearly a decade of planning and construction, Cleveland Clinic Abu Dhabi opened its doors. By...
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Keywords:
Organizational Behavior;
Culture;
Alignment;
Organizational Effectiveness;
Purpose;
Impact;
Leadership Development;
Diversity;
Collaboration;
Co-creation;
Learning Organizations;
Empowerment;
Teams;
Team Dynamics;
Teamwork;
Team Effectiveness;
Trust;
Talent;
Talent Development And Retention;
Psychological Safety;
Organizational Evolution;
Coaching;
Board;
Analytics;
Innovation;
Data;
Data Visualization;
Digital Technology;
Digital;
Customer Experience;
Experimentation;
Change Management;
Data-driven Decision-making;
Debates;
Ecosystem;
Partnership;
Telemedicine;
Sustainability;
Global Organizations;
Local;
Hospital;
Healthcare;
United Arab Emirates;
Health Care and Treatment;
Partners and Partnerships;
Globalization;
Quality;
Organizational Culture;
Mission and Purpose;
Innovation and Management;
Information Technology;
Joint Ventures;
Leadership;
Performance Effectiveness;
Abu Dhabi;
United Arab Emirates
Hill, Linda A., and Emily Tedards. "Cleveland Clinic Abu Dhabi." Harvard Business School Case 422-058, February 2022.
- February 2022
- Case
Cleveland Clinic Abu Dhabi (Abridged)
By: Linda A. Hill and Emily Tedards
In 2006, the Cleveland Clinic and Mubadala Investment Company partnered with a bold ambition to deliver world class healthcare in the United Arab Emirates. In 2015, after nearly a decade of planning and construction, Cleveland Clinic Abu Dhabi opened its doors. By...
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Keywords:
Organization Behavior;
Culture;
Alignment;
Organizational Effectiveness;
Purpose;
Impact;
Leadership Development;
Diversity;
Collaboration;
Co-creation;
Learning Organizations;
Empowerment;
Teams;
Team Dynamics;
Teamwork;
Team Effectiveness;
Trust;
Talent;
Talent Development And Retention;
Psychological Safety;
Organizational Evolution;
Coaching;
Board;
Analytics;
Innovation;
Data;
Data Visualization;
Digital Technology;
Digital;
Customer Experience;
Experimentation;
Change Management;
Data-driven Decision-making;
Debates;
Ecosystem;
Partnership;
Telemedicine;
Sustainability;
Global Organizations;
Local;
Hospital;
Healthcare;
United Arab Emirates;
Health Care and Treatment;
Partners and Partnerships;
Globalization;
Quality;
Organizational Culture;
Mission and Purpose;
Innovation and Management;
Information Technology;
Joint Ventures;
Leadership;
Performance Effectiveness;
Abu Dhabi;
United Arab Emirates
Hill, Linda A., and Emily Tedards. "Cleveland Clinic Abu Dhabi (Abridged)." Harvard Business School Case 422-056, February 2022.