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- Faculty Publications (136)
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- All HBS Web (197)
- Faculty Publications (136)
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- October 2016 (Revised November 2018)
- Case
Indigo Agriculture
By: Marco Iansiti, Michael W. Toffel and Christine Snively
Indigo Agriculture had successfully developed and launched its first commercial product, microbe-enhanced cotton seeds, on an accelerated product development timeline. In late 2016, as the company was about to launch its second product, winter wheat, the management...
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Keywords:
Product Development;
Agribusiness;
Science-Based Business;
Operations;
Management;
Agriculture and Agribusiness Industry;
Technology Industry
Iansiti, Marco, Michael W. Toffel, and Christine Snively. "Indigo Agriculture." Harvard Business School Case 617-020, October 2016. (Revised November 2018.)
- August 2020 (Revised January 2022)
- Case
1928 Diagnostics: Fighting Antibiotics Resistance
By: Ariel D. Stern and Daniela Beyersdorfer
In 2019, the co-founders of the Swedish medical start-up 1928 Diagnostics, CEO Dr. Kristina Lagerstedt and COO Dr. Susanne Staaf, had to pick the right business model to commercialize their novel technology to hospitals and health care providers. Developed in...
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Keywords:
Health Care and Treatment;
Entrepreneurship;
Leadership;
Science-Based Business;
Growth and Development Strategy;
Business Growth and Maturation;
Business Model;
Information Technology;
Digital Platforms;
Health Disorders;
Market Entry and Exit;
Value Creation;
Business and Stakeholder Relations;
Health Industry;
Medical Devices and Supplies Industry;
Technology Industry;
Europe;
Sweden
Stern, Ariel D., and Daniela Beyersdorfer. "1928 Diagnostics: Fighting Antibiotics Resistance." Harvard Business School Case 621-025, August 2020. (Revised January 2022.)
- 17 Oct 2012
- Research & Ideas
America Needs a Manufacturing Renaissance
Editor's note: In their new book, Producing Prosperity: Why America Needs a Manufacturing Renaissance, Harvard Business School professors Gary P. Pisano and Willy C. Shih argue that reinvesting in America's manufacturing prowess is...
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- February 2024
- Supplement
Seeds of Innovation: GALY’s Quest to Cultivate the Future of Agriculture in the Lab
By: George Serafeim
In 2023, Luciano Bueno, CEO and founder of plant cell culture agriculture company GALY, was considering the best path forward for his company as he planned to pitch Series B investors. GALY, founded in 2019, aimed to produce cotton and other crops from cells grown in...
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Keywords:
Business Model;
Green Technology;
Goods and Commodities;
Growth and Development Strategy;
Science-Based Business;
Entrepreneurship;
Plant-Based Agribusiness;
Business Startups;
Decisions;
Technological Innovation;
Production;
Entrepreneurial Finance;
Agriculture and Agribusiness Industry;
Technology Industry;
Boston;
Sao Paulo
Serafeim, George. "Seeds of Innovation: GALY's Quest to Cultivate the Future of Agriculture in the Lab." Harvard Business School Multimedia/Video Supplement 124-705, February 2024.
- 24 Sep 2007
- Research & Ideas
The FDA: What Will the Next 100 Years Bring?
facilities each year, an increasing number of which are on foreign soil. "Without the FDA, each of us would individually spend a lot more time researching where products come from and what ingredients they contain," says Harvard Business...
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- January 2001
- Case
Abgenix and the XenoMouse
By: Robert J. Dolan
Abgenix has a unique method for generating antibodies useful in treating a number of diseases, including cancer. In early 2000, the company's cancer has performed very well in animal testing and is moving to early stage human testing. Abgenix must decide whether to...
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Keywords:
Product Development;
Marketing Strategy;
Health Testing and Trials;
Risk and Uncertainty;
Technological Innovation;
Innovation Strategy;
Science-Based Business;
Biotechnology Industry
Dolan, Robert J. "Abgenix and the XenoMouse." Harvard Business School Case 501-061, January 2001.
- October 2004 (Revised March 2005)
- Case
Langer Lab, The: Commercializing Science
By: H. Kent Bowen, Alex Kazaks, Ayr Muir-Harmony and Bryce LaPierre
Professor Robert Langer's laboratory at MIT is the source of an unusually large number of published papers, patents, and technology licenses to start-up and established companies in the biomedical industry. Explores Langer's leadership and other factors that create a...
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Keywords:
Entrepreneurship;
Technological Innovation;
Business Startups;
Research and Development;
Patents;
Innovation Leadership;
Science-Based Business;
Commercialization;
Biotechnology Industry;
Education Industry
Bowen, H. Kent, Alex Kazaks, Ayr Muir-Harmony, and Bryce LaPierre. "Langer Lab, The: Commercializing Science." Harvard Business School Case 605-017, October 2004. (Revised March 2005.)
- September 2023 (Revised April 2024)
- Case
Atomwise: Strategic Opportunities in AI for Pharma
By: Satish Tadikonda
Abraham Heifets and his co-founder, Izhar Wallach, had founded Atomwise to develop i) an AI engine to transform drug discovery by creating better medicines faster, and ii) a machine learning-based discovery engine that combined the power of convolutional neural...
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Keywords:
Business Model;
Business Startups;
AI and Machine Learning;
Science-Based Business;
Biotechnology Industry;
Pharmaceutical Industry
Tadikonda, Satish. "Atomwise: Strategic Opportunities in AI for Pharma." Harvard Business School Case 824-043, September 2023. (Revised April 2024.)
- January 2017
- Case
Danaher Corporation, 2007–2017
By: John R. Wells and Gabriel Ellsworth
On July 2, 2016, Danaher Corporation completed the spinoff of Fortive Corporation. The previous day, Danaher’s stock price had reached an all-time high. In 2015, Danaher had decided to split off its test and measurement, fuel and fleet management, and automation...
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Keywords:
Danaher;
Fortive;
Larry Culp;
Beckman Coulter;
Pall;
Life Sciences;
Diagnostics;
Environmental Operations;
Water Management;
Dental;
Testing;
Measurement;
Fuel;
Fleet Management;
Automation;
Toolmaking;
Tools;
Disease Management;
Continuous Improvement;
Toyota Production System;
Divestiture;
Spinoffs;
Spin-off;
Networks;
Acquisition;
Mergers and Acquisitions;
Business Conglomerates;
Business Divisions;
Business Subsidiaries;
Business Units;
Business Growth and Maturation;
Business Model;
For-Profit Firms;
Joint Ventures;
Restructuring;
Engineering;
Chemicals;
Construction;
Machinery and Machining;
Profit;
Revenue;
Globalized Firms and Management;
Multinational Firms and Management;
Health;
Health Care and Treatment;
Health Disorders;
Medical Specialties;
Business History;
Job Cuts and Outsourcing;
Business or Company Management;
Growth and Development Strategy;
Management Analysis, Tools, and Techniques;
Management Practices and Processes;
Management Succession;
Management Systems;
Resource Allocation;
Market Entry and Exit;
Measurement and Metrics;
Logistics;
Business Processes;
Organizational Change and Adaptation;
Public Ownership;
Problems and Challenges;
Science;
Genetics;
Natural Environment;
Wastes and Waste Processing;
Science-Based Business;
Opportunities;
Strategy;
Adaptation;
Business Strategy;
Competition;
Competitive Strategy;
Competitive Advantage;
Consolidation;
Corporate Strategy;
Diversification;
Expansion;
Technology;
Software;
Technology Networks;
Technology Platform;
Value;
Valuation;
Aerospace Industry;
Auto Industry;
Biotechnology Industry;
Chemical Industry;
Computer Industry;
Construction Industry;
Consumer Products Industry;
Distribution Industry;
Electronics Industry;
Food and Beverage Industry;
Health Industry;
Industrial Products Industry;
Information Technology Industry;
Manufacturing Industry;
Medical Devices and Supplies Industry;
Pharmaceutical Industry;
Retail Industry;
Rubber Industry;
Semiconductor Industry;
Shipping Industry;
Technology Industry;
Telecommunications Industry;
Utilities Industry;
United States;
District of Columbia
Wells, John R., and Gabriel Ellsworth. "Danaher Corporation, 2007–2017." Harvard Business School Case 717-464, January 2017.
- February 2020 (Revised March 2020)
- Case
Prime Coalition: Catalytic Capital for Climate Innovation
By: Ramana Nanda, Benjamin N. Roth and Olivia Hull
With long development timelines and high risk, new energy technologies were often left to languish in the “valley of death,” unable to raise enough funds to bring a product to market. In 2014, Sarah Kearney founded the nonprofit Prime Coalition to solve this problem....
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Keywords:
Energy Conservation;
Renewable Energy;
Social Entrepreneurship;
Venture Capital;
Investment;
Innovation and Invention;
Technological Innovation;
Mission and Purpose;
Science-Based Business;
Nonprofit Organizations;
Social Enterprise;
Energy Industry;
Technology Industry;
Green Technology Industry;
United States
Nanda, Ramana, Benjamin N. Roth, and Olivia Hull. "Prime Coalition: Catalytic Capital for Climate Innovation." Harvard Business School Case 820-007, February 2020. (Revised March 2020.)
- May 2009 (Revised August 2013)
- Case
The DiagnoFirst Opportunity
By: Robert C. Pozen and Rukmini Balu
John Mason, a principle at Oldwell Partners, was facing a decision of whether or not to invest in DiagnoFirst, a molecular diagnostics firm. DiagnoFirst's key product was a genetic test that identified a subset of prostate cancer patients with a high risk of clinical...
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Keywords:
Genetic Engineering;
Genetically Modified;
Genomics;
Venture Capital;
Patents;
Genetics;
Decision Choices and Conditions;
Laws and Statutes;
Investment;
Science-Based Business;
Biotechnology Industry
Pozen, Robert C., and Rukmini Balu. "The DiagnoFirst Opportunity." Harvard Business School Case 309-112, May 2009. (Revised August 2013.)
- 29 Jul 2008
- First Look
First Look: July 29, 2008
the impact of technology shifts on those boundaries, with significant implications for the incumbents. Purchase this case: http://www.hbsp.harvard.edu/b01/en/common/item_detail.jhtml?id=608159 Symyx Technologies, Inc. Harvard Business...
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Keywords:
Martha Lagace
- 20 Oct 2003
- Research & Ideas
Gaps in the Historical Record: Development of the Electronics Industry
In a recently published book on current international research in business history, edited by Harvard Business School professor Geoffrey Jones, HBS professor emeritus Alfred D. Chandler Jr. contributed an...
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- April 2009
- Case
GSK's Acquisition of Sirtris: Independence or Integration?
By: Toby E. Stuart and James Weber
An executive from pharmaceutical company GSK must choose how much to integrate a recently acquired biotechnology firm, Sirtris. Moncef Slaoui, GSK's global head of R&D, championed the acquisition of Sirtris to gain access to its potentially revolutionary science....
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Keywords:
Mergers and Acquisitions;
Resource Allocation;
Organizational Change and Adaptation;
Organizational Culture;
Organizational Structure;
Research and Development;
Science-Based Business;
Integration
Stuart, Toby E., and James Weber. "GSK's Acquisition of Sirtris: Independence or Integration?" Harvard Business School Case 809-026, April 2009.
- March 2024
- Case
Biomanufacturing Decentralization by Stämm
By: Paul A. Gompers, Jenyfeer Martínez Buitrago and Mariana Cal
In Buenos Aires, Argentina, cousins Llamazares and D’Alvia founded Stämm, a startup based on the idea of decentralizing biomanufacturing processes and downsizing biotech facilities. After raising its seed and series A rounds, and while finalizing its series B round in...
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Keywords:
Business Model;
Business Startups;
Entrepreneurship;
Venture Capital;
Selection and Staffing;
Technological Innovation;
Science-Based Business;
Business Strategy;
Commercialization;
Growth and Development Strategy;
Product Launch;
Research and Development;
Biotechnology Industry;
Latin America;
South America;
Argentina;
Buenos Aires
- October 2012
- Case
GSK's Acquisition of Sirtris: Independence or Integration? (Abridged)
By: Toby Stuart and James Weber
An executive from pharmaceutical company GSK must choose how much to integrate a recently acquired biotechnology firm, Sirtris. Moncef Slaoui, GSK's global head of R&D, championed the acquisition of Sirtris to gain access to its potentially revolutionary science....
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Keywords:
Mergers and Acquisitions;
Resource Allocation;
Organizational Change and Adaptation;
Organizational Culture;
Organizational Structure;
Research and Development;
Science-Based Business;
Integration
Stuart, Toby, and James Weber. "GSK's Acquisition of Sirtris: Independence or Integration? (Abridged)." Harvard Business School Case 813-028, October 2012.
- 04 Apr 2017
- First Look
First Look at New Research, April 4
businesses have led the venture capital model to adapt in fundamental ways over the prior decade. We both document and provide a framework to understand the changes in the investment strategy of VCs in recent years—an increased prevalence...
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Keywords:
Sean Silverthorne
- November 2023 (Revised March 2024)
- Case
Infarm: Betting the (Indoor) Farm on Food Security
By: Elie Ofek
In the summer of 2023, the co-founders of Infarm, a controlled environment agriculture (CEA) company, were contemplating a major pivot going forward. While Infarm had successfully shown it could grow over 75 products—mainly herbs, leafy greens and mushrooms—in modular...
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Keywords:
Plant-Based Agribusiness;
Business Model;
Market Entry and Exit;
Science-Based Business;
Business Strategy;
Transition;
Agriculture and Agribusiness Industry;
Europe;
North America;
Toronto;
Northeastern United States
Ofek, Elie. "Infarm: Betting the (Indoor) Farm on Food Security." Harvard Business School Case 524-043, November 2023. (Revised March 2024.)
- 31 May 2016
- HBS Case
Who Owns Space?
New Space sector: namely, to use it as a means of launching classroom discussion and research on the subtleties and challenges of the relationship between the public and private sectors. An associate professor of business administration...
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- November 1983 (Revised May 1984)
- Case
SSS (Scientific Systems Services)
By: Howard H. Stevenson and Michael J. Roberts
Keywords:
Science-Based Business
Stevenson, Howard H., and Michael J. Roberts. "SSS (Scientific Systems Services)." Harvard Business School Case 384-129, November 1983. (Revised May 1984.)