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- Faculty Publications (136)
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- All HBS Web (197)
- Faculty Publications (136)
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- November 2001
- Case
Aventis CropScience and StarLink Corn
By: Ray A. Goldberg and James M Beagle
Aventis CropScience responds to the discovery of an unapproved corn variety in food supplies and draws lessons for the company, industry, and governments.
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- November 2023 (Revised April 2024)
- Case
BiomX: Bringing Phage Back to the Stage
By: Paul A. Gompers, Elie Ofek, Orna Dan and Emilie Billaud
In the spring of 2023, and following the favorable results of a trial involving its phage cocktail for treating lung infections among cystic fibrosis (CF) patients, the leadership of BiomX had several critical issues to wrestle with. First, given its precarious...
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Keywords:
Working Capital;
Financing and Loans;
Health Testing and Trials;
Product Development;
Research and Development;
Science-Based Business;
Commercialization;
Biotechnology Industry;
Pharmaceutical Industry
Gompers, Paul A., Elie Ofek, Orna Dan, and Emilie Billaud. "BiomX: Bringing Phage Back to the Stage." Harvard Business School Case 524-051, November 2023. (Revised April 2024.)
- 2010
- Working Paper
From Bench to Board: Gender Differences in University Scientists' Participation in Commercial Science
This paper examines gender differences in the participation of university life science faculty in commercial science. Based on theory and field interviews, we develop hypotheses regarding how scientists' productivity, co-authorship networks, and institutional...
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Keywords:
Business Startups;
For-Profit Firms;
Gender Characteristics;
Higher Education;
Entrepreneurship;
Governing and Advisory Boards;
Science-Based Business;
Nonprofit Organizations;
Biotechnology Industry
Ding, Waverly W., Fiona Murray, and Toby E. Stuart. "From Bench to Board: Gender Differences in University Scientists' Participation in Commercial Science." Harvard Business School Working Paper, No. 11-014, August 2010.
- 17 Feb 2010
- First Look
First Look: Feb. 17
Working PapersThe Evolution of Science-Based Business: Innovating How We Innovate Author:Gary P. Pisano An abstract in unavailable at this time. Download the paper: http://www.hbs.edu/research/pdf/10-062.pdf PublicationsTargeted...
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Keywords:
Martha Lagace
- October 2016 (Revised November 2016)
- Case
Innovating Beyond Ochsner
By: Richard G. Hamermesh and Olivia Hull
The Ochsner Health System has developed a proprietary software tool designed to treat hypertension. Built into the system’s electronic medical records, the Hypertension Digital Medicine program allows patients to record their blood pressure at home and share readings...
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Keywords:
Electronic Medical Records;
Telemedicine;
Hypertension;
High Blood Pressure;
Chronic Disease;
Entrepreneurship;
Health Disorders;
Business Model;
Business Startups;
Innovation and Invention;
Growth Management;
Marketing Strategy;
Product Launch;
Product Positioning;
Science-Based Business;
Business Strategy;
Health Industry;
Technology Industry;
New Orleans;
Louisiana
Hamermesh, Richard G., and Olivia Hull. "Innovating Beyond Ochsner." Harvard Business School Case 817-028, October 2016. (Revised November 2016.)
- January 2011 (Revised July 2012)
- Case
Arcadia Biosciences: Seeds of Change (Abridged)
By: Arthur A. Daemmrich
Arcadia Biosciences is seeking to introduce genetically modified rice to China that will lower farmers' costs and generate environmental benefits through reduced greenhouse gas emissions. The case describes challenges facing this small agricultural biotechnology...
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Keywords:
Plant-Based Agribusiness;
Intellectual Property;
Genetics;
Environmental Sustainability;
Science-Based Business;
Climate Change;
Agriculture and Agribusiness Industry;
Biotechnology Industry;
China
Daemmrich, Arthur A. "Arcadia Biosciences: Seeds of Change (Abridged)." Harvard Business School Case 711-050, January 2011. (Revised July 2012.)
- 22 Apr 2008
- First Look
First Look: April 22, 2008
Business Harvard Business School Case 608-136 Novartis is a science-based drug company, which has important implications for its business...
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Keywords:
Martha Lagace
- July 1997 (Revised June 2001)
- Case
H.E. Butt Grocery Company: A Leader in ECR Implementation (B) (Abridged)
By: Robert D. Austin and F. Warren McFarlan
H.E. Butt Grocery Co. led the grocery industry in adopting many innovations, including category management, electronic data interchange, and continuous replenishment. They have also moved aggressively and profitably into newer applications such as Scanner-based payment...
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Keywords:
Information Management;
Independent Innovation and Invention;
Innovation and Invention;
Business Organization;
Risk and Uncertainty;
Science-Based Business;
Cross-Cultural and Cross-Border Issues;
Management Analysis, Tools, and Techniques;
Risk Management;
Electronics Industry;
Computer Industry
Austin, Robert D., and F. Warren McFarlan. "H.E. Butt Grocery Company: A Leader in ECR Implementation (B) (Abridged)." Harvard Business School Case 198-016, July 1997. (Revised June 2001.)
- July 2011 (Revised January 2013)
- Case
Digital Microscopy Is Making Me Crazy!
By: Willy Shih
For Carl Zeiss Microimaging, modular hardware and software enabled customers to tailor Zeiss's broad range of microscopy systems hardware and software to meet a wide range of needs from basic scientific research in the biological and medical sciences to clinical...
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Keywords:
Information Infrastructure;
Applications and Software;
Corporate Strategy;
Disruptive Innovation;
Science-Based Business;
Management Analysis, Tools, and Techniques;
Business Conglomerates;
Digital Platforms;
Opportunities;
Medical Devices and Supplies Industry;
Computer Industry
Shih, Willy. "Digital Microscopy Is Making Me Crazy!" Harvard Business School Case 612-002, July 2011. (Revised January 2013.)
- October 2019 (Revised November 2019)
- Case
C16 Biosciences: Lab-Grown Palm Oil
By: Jeffrey J. Bussgang and Olivia Hull
Synthetic biology start-up C16 Biosciences wants to solve a big problem: replace palm oil, a major contributor to deforestation and climate change, with a lab-grown substitute. CEO Shara Ticku has ambitious plans to supply her lab-grown palm oil to food manufacturers,...
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Keywords:
Science-Based Business;
Environmental Sustainability;
Social Entrepreneurship;
Product Development;
Product Positioning;
Venture Capital;
Strategy;
Decision Making;
Food and Beverage Industry;
Consumer Products Industry
Bussgang, Jeffrey J., and Olivia Hull. "C16 Biosciences: Lab-Grown Palm Oil." Harvard Business School Case 820-008, October 2019. (Revised November 2019.)
- 28 Feb 2019
- Cold Call Podcast
Pursuing Precision Medicine at Intermountain Healthcare
- October 1998 (Revised December 1999)
- Case
Gene Research, the Mapping of Life and the Global Economy
By: Ray A. Goldberg and Juan Enriquez-Cabot
A new firm is being created to speed up the process of mapping humans, animals, and plants by combining gene technology with rapid gene identification to improve the health and well being of the human population and the productivity of crops and animals. How does one...
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Keywords:
Information Technology;
Organizational Structure;
Technological Innovation;
Business Processes;
Health Care and Treatment;
Performance Productivity;
Welfare;
Agribusiness;
Genetics;
Science-Based Business;
Biotechnology Industry;
Agriculture and Agribusiness Industry
Goldberg, Ray A., and Juan Enriquez-Cabot. "Gene Research, the Mapping of Life and the Global Economy." Harvard Business School Case 599-016, October 1998. (Revised December 1999.)
- November 2009 (Revised December 2009)
- Case
GTC Biotherapeutics: Developing Medicines in the Milk of Goats
By: Ray A. Goldberg and Sarah Morton
GTC is the first company in the animal world to receive FDA approval of a transgenic pharmaceutical. What are the implications for other firms in plants and animals and their opportunities to produce new medicines in an economical and safe fashion?
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Keywords:
Health Care and Treatment;
Animal-Based Agribusiness;
Plant-Based Agribusiness;
Science-Based Business;
Medical Specialties;
Product;
Technological Innovation;
Health Industry;
Pharmaceutical Industry;
United States
Goldberg, Ray A., and Sarah Morton. "GTC Biotherapeutics: Developing Medicines in the Milk of Goats." Harvard Business School Case 910-403, November 2009. (Revised December 2009.)
- 2009
- Working Paper
Social Influence Given (Partially) Deliberate Matching: Career Imprints in the Creation of Academic Entrepreneurs
By: Pierre Azoulay, Christopher C. Liu and Toby E. Stuart
Actors often match with associates on a small set of dimensions that matter most for the particular relationship at hand. In so doing, they are exposed to unanticipated social influences because counterparts have more interests, attitudes, and preferences than would-be...
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Keywords:
Entrepreneurship;
Patents;
Marketplace Matching;
Mathematical Methods;
Science-Based Business;
Power and Influence;
Social and Collaborative Networks;
Biotechnology Industry
Azoulay, Pierre, Christopher C. Liu, and Toby E. Stuart. "Social Influence Given (Partially) Deliberate Matching: Career Imprints in the Creation of Academic Entrepreneurs." Harvard Business School Working Paper, No. 09-136, May 2009.
- June 2019
- Teaching Note
Zebra Medical Vision
By: Shane Greenstein and Sarah Gulick
Teaching note is meant to accompany Zebra Medical Vision case, which offers a look at a company’s decisions as a small startup competing with other startups and major technology companies. It also demonstrates the challenges faced by a machine learning company working...
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- October 2012
- Teaching Plan
Vertex Pharmaceuticals and the Cystic Fibrosis Foundation: Venture Philanthropy Funding for Biotech (TP)
By: Robert F. Higgins
This is the teaching note related to HBS case 808005. In 2001, Vertex Pharmaceuticals Incorporated acquired the San Diego-based biotech company, Aurora Biosciences. The combination of Vertex's and Aurora's technologies would improve the flow of novel drug candidates...
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Keywords:
Venture Philanthropy;
Biotechnology;
Funding Philanthropy Venture;
Cystic Fibrosis;
Foundations;
Pharmaceuticals;
Mergers and Acquisitions;
For-Profit Firms;
Venture Capital;
Philanthropy and Charitable Giving;
Science-Based Business;
Nonprofit Organizations;
Pharmaceutical Industry;
Biotechnology Industry;
United States;
San Diego
- 2008
- Chapter
The Evidence Does Not Speak for Itself: Expert Witnesses and the Organization of DNA-Typing Companies
By: Arthur A. Daemmrich
During the past 15 years, new biotechnology companies have promoted DNA typing as a sophisticated criminal and paternity identification technique. Private testing laboratories produce results that link individuals with crime scenes and fathers to their children....
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- 2015
- Case
Advanced Leadership Pathways: Torsten Thiele and the Global Ocean Trust
By: Rosabeth Moss Kanter and Brian Hoffstein
Following a successful career in finance, Torsten Thiele devoted himself full-time to the challenging cause of ocean conservation and stewardship. In August 2015, Thiele had already come a long way in spearheading initiatives towards the protection of the ocean: from...
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Keywords:
Environment;
Natural Environment;
Environmental Sustainability;
Pollutants;
Science-Based Business;
Climate Change;
Social Enterprise;
Leadership
Kanter, Rosabeth Moss, and Brian Hoffstein. "Advanced Leadership Pathways: Torsten Thiele and the Global Ocean Trust." Harvard Business Publishing Case 316-039, 2015. (Harvard Advanced Leadership Initiative.)
- February 2020
- Supplement
Indigo Agriculture: Harnessing Nature
By: Michael W. Toffel and James Barnett
Indigo Agriculture used a digital-enabled research and development (R&D) process to launch its initial product, microbial coatings for agricultural seeds, which increase crop yields while reducing the need for fertilizers. In doing so, the company developed direct...
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Keywords:
Operations;
Supply Chain;
Social Enterprise;
Product Development;
Distribution Channels;
Business Strategy;
Digital Platforms;
Environmental Sustainability;
Science-Based Business;
Climate Change;
Agriculture and Agribusiness Industry;
Green Technology Industry;
United States;
Massachusetts
- February 2014
- Case
BGI: Data-driven Research
By: Willy Shih and Sen Chai
BGI has the largest installed gene-sequencing capacity in the world, and to Zhang Gengyun, general manager of the Life Sciences Division, this represented an opportunity to apply his training as a plant breeder and his early career work as a biochemist to improving...
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Keywords:
Genomics;
Gene Sequencing;
Life Sciences;
Plant Breeding;
Human Genome Program;
Beijing Genomics Institute;
BGI;
Rice Genome;
Technological Innovation;
Innovation Strategy;
Research;
Research and Development;
Science;
Genetics;
Science-Based Business;
Strategy;
Commercialization;
Corporate Strategy;
Information Technology;
Applications and Software;
Agriculture and Agribusiness Industry;
Biotechnology Industry;
Food and Beverage Industry;
China;
United States
Shih, Willy, and Sen Chai. "BGI: Data-driven Research." Harvard Business School Case 614-056, February 2014.