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- Faculty Publications (145)
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- All HBS Web (207)
- Faculty Publications (145)
- 2010
- Working Paper
Boundary Spanning in a For-profit Research Lab: An Exploration of the Interface Between Commerce and Academe
By: Christopher C. Liu and Toby E. Stuart
In innovative industries, private-sector companies increasingly are participants in open communities of science and technology. To participate in the system of exchange in such communities, firms often publicly disclose what would otherwise remain private discoveries....
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Keywords:
For-Profit Firms;
Higher Education;
Information Publishing;
Innovation and Invention;
Science-Based Business;
Social and Collaborative Networks;
Boundaries;
Biotechnology Industry;
Pharmaceutical Industry
Liu, Christopher C., and Toby E. Stuart. "Boundary Spanning in a For-profit Research Lab: An Exploration of the Interface Between Commerce and Academe." Harvard Business School Working Paper, No. 11-012, August 2010.
- February 2020
- Supplement
Indigo Agriculture: Harnessing Nature
By: Michael W. Toffel and James Barnett
Indigo Agriculture used a digital-enabled research and development (R&D) process to launch its initial product, microbial coatings for agricultural seeds, which increase crop yields while reducing the need for fertilizers. In doing so, the company developed direct...
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Keywords:
Operations;
Supply Chain;
Social Enterprise;
Product Development;
Distribution Channels;
Business Strategy;
Digital Platforms;
Environmental Sustainability;
Science-Based Business;
Climate Change;
Agriculture and Agribusiness Industry;
Green Technology Industry;
United States;
Massachusetts
- August 1991 (Revised March 1993)
- Case
Champion International Corp.: Timber, Trade, and the Northern Spotted Owl
Champion's forest products division owns timberlands, sawmills, and plywood mills in the Pacific Northwest. The listing of the northern spotted owl as an endangered species, and restrictions on exports of logs from state-owned lands, have disrupted the stumpage, log...
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Keywords:
Science-Based Business;
Natural Environment;
Product Marketing;
Governing Rules, Regulations, and Reforms;
Government and Politics;
Environmental Sustainability;
Corporate Strategy;
Trade;
Decisions;
Management Teams;
Forest Products Industry;
North and Central America
Reinhardt, Forest L. "Champion International Corp.: Timber, Trade, and the Northern Spotted Owl." Harvard Business School Case 792-017, August 1991. (Revised March 1993.)
- September 2023 (Revised November 2023)
- Case
Seeds of Innovation: GALY's Quest to Cultivate the Future of Agriculture in the Lab
By: George Serafeim and Michael Norris
In 2023, Luciano Bueno, CEO and founder of plant cell culture agriculture company GALY, was considering the best path forward for his company as he planned to pitch Series B investors. GALY, founded in 2019, aimed to produce cotton and other crops from cells grown in...
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Keywords:
Business Model;
Green Technology;
Goods and Commodities;
Growth and Development Strategy;
Science-Based Business;
Entrepreneurship;
Plant-Based Agribusiness;
Business Startups;
Decisions;
Technological Innovation;
Production;
Agriculture and Agribusiness Industry;
Technology Industry;
Boston;
Sao Paulo
Serafeim, George, and Michael Norris. "Seeds of Innovation: GALY's Quest to Cultivate the Future of Agriculture in the Lab." Harvard Business School Case 124-017, September 2023. (Revised November 2023.)
- November 2023 (Revised April 2024)
- Case
BiomX: Bringing Phage Back to the Stage
By: Paul A. Gompers, Elie Ofek, Orna Dan and Emilie Billaud
In the spring of 2023, and following the favorable results of a trial involving its phage cocktail for treating lung infections among cystic fibrosis (CF) patients, the leadership of BiomX had several critical issues to wrestle with. First, given its precarious...
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Keywords:
Working Capital;
Financing and Loans;
Health Testing and Trials;
Product Development;
Research and Development;
Science-Based Business;
Commercialization;
Biotechnology Industry;
Pharmaceutical Industry
Gompers, Paul A., Elie Ofek, Orna Dan, and Emilie Billaud. "BiomX: Bringing Phage Back to the Stage." Harvard Business School Case 524-051, November 2023. (Revised April 2024.)
- 17 Jul 2012
- First Look
First Look: July 17
Science-Based Business (Abridged) Ananth Raman and Inga MaurerHarvard Business School Case 611-027 Ray Gilmartin faces a dilemma. His company's credibility has been damaged by the recent withdrawal of Vioxx, a multi-billion dollar drug....
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Keywords:
Sean Silverthorne
- November 2012
- Case
CSIRO: The Light Metals Flagship Decision
By: Willy Shih, Margaret P. Pierson and Dawn Lau
This case explores the challenge of investing in basic research as a public good. CSIRO was Australia's leading science and research agency, and it was chartered to enhance national prosperity through R&D. Its Flagships program was designed to align research interests...
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Keywords:
R&D;
Basic Research;
Government-funded Research;
Public Goods;
Extractive Industries;
Metals;
Metals Processing;
Decision Choices and Conditions;
Decisions;
Globalized Markets and Industries;
Growth and Development;
Innovation Strategy;
Technological Innovation;
Research and Development;
Science-Based Business;
Technology Adoption;
Technology Platform;
Manufacturing Industry;
Mining Industry;
Oceania;
Australia
Shih, Willy, Margaret P. Pierson, and Dawn Lau. "CSIRO: The Light Metals Flagship Decision." Harvard Business School Case 613-029, November 2012.
- November 2016 (Revised November 2016)
- Case
Radial Analytics Probes Post-Acute Care
By: Richard G. Hamermesh and Olivia Hull
Thaddeus Fulford-Jones and Eric Weiss, founders of healthcare technology startup Radial Analytics, have been busy developing a software program designed to save hospitals money and improve patient outcomes by producing customized care plans for patients leaving the...
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Keywords:
Electronic Medical Records;
Electronic Health Records;
Data Science;
Entrepreneurship;
Health Care and Treatment;
Business Model;
Business Startups;
Innovation and Invention;
Growth Management;
Marketing Strategy;
Product Launch;
Product Positioning;
Science-Based Business;
Business Strategy;
Health Industry;
Technology Industry;
Cambridge;
Massachusetts
Hamermesh, Richard G., and Olivia Hull. "Radial Analytics Probes Post-Acute Care." Harvard Business School Case 817-029, November 2016. (Revised November 2016.)
- 29 Jul 2008
- First Look
First Look: July 29, 2008
the impact of technology shifts on those boundaries, with significant implications for the incumbents. Purchase this case: http://www.hbsp.harvard.edu/b01/en/common/item_detail.jhtml?id=608159 Symyx Technologies, Inc. Harvard Business School Case 608-152 Symyx is a...
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Keywords:
Martha Lagace
- October 2016 (Revised November 2016)
- Case
Innovating Beyond Ochsner
By: Richard G. Hamermesh and Olivia Hull
The Ochsner Health System has developed a proprietary software tool designed to treat hypertension. Built into the system’s electronic medical records, the Hypertension Digital Medicine program allows patients to record their blood pressure at home and share readings...
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Keywords:
Electronic Medical Records;
Telemedicine;
Hypertension;
High Blood Pressure;
Chronic Disease;
Entrepreneurship;
Health Disorders;
Business Model;
Business Startups;
Innovation and Invention;
Growth Management;
Marketing Strategy;
Product Launch;
Product Positioning;
Science-Based Business;
Business Strategy;
Health Industry;
Technology Industry;
New Orleans;
Louisiana
Hamermesh, Richard G., and Olivia Hull. "Innovating Beyond Ochsner." Harvard Business School Case 817-028, October 2016. (Revised November 2016.)
- July 2004 (Revised March 2006)
- Case
RosettaNet and ebXML: Betting on the Right eBusiness Standard
By: F. Warren McFarlan and Veronika Belokhvostova
A major enterprise software company must select which technologies to support, based on their long-term and short-term viability and benefits. The protagonist is involved in the release of the B2B integration component of major enterprise software whose purpose is to...
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Keywords:
Communication Technology;
Customer Focus and Relationships;
Markets;
Standards;
Science-Based Business;
Situation or Environment;
Applications and Software;
Technology Adoption;
Information Technology Industry
McFarlan, F. Warren, and Veronika Belokhvostova. "RosettaNet and ebXML: Betting on the Right eBusiness Standard." Harvard Business School Case 305-006, July 2004. (Revised March 2006.)
- April 2009
- Case
GSK's Acquisition of Sirtris: Independence or Integration?
By: Toby E. Stuart and James Weber
An executive from pharmaceutical company GSK must choose how much to integrate a recently acquired biotechnology firm, Sirtris. Moncef Slaoui, GSK's global head of R&D, championed the acquisition of Sirtris to gain access to its potentially revolutionary science....
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Keywords:
Mergers and Acquisitions;
Resource Allocation;
Organizational Change and Adaptation;
Organizational Culture;
Organizational Structure;
Research and Development;
Science-Based Business;
Integration
Stuart, Toby E., and James Weber. "GSK's Acquisition of Sirtris: Independence or Integration?" Harvard Business School Case 809-026, April 2009.
- Research Summary
Overview
By: Kyle R. Myers
Professor Myers studies the economics of what determines the rate and direction of innovation. He has examined the reallocation of scientists through the use of targeted research grants at the National Institutes of Health, and is working to further understand how...
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Keywords:
Technology Networks;
Commercialization;
Science-Based Business;
Research and Development;
Knowledge Management;
Patents;
Innovation Strategy;
Technological Innovation;
Health Care and Treatment;
Entrepreneurship;
Health;
Innovation and Invention;
Science;
Technology;
Knowledge;
Intellectual Property;
Economics;
Microeconomics;
Biotechnology Industry;
Health Industry;
Pharmaceutical Industry;
Technology Industry
- January 2024
- Case
Fusion Industry Association: Igniting the Future of Clean Energy
Fusion energy is evolving from a scientific idea to a commercial possibility, drawing large investments and regulatory discussions; how should the FIA navigate this evolution?
The Fusion Industry Association (FIA) is at the forefront of transforming fusion... View Details
The Fusion Industry Association (FIA) is at the forefront of transforming fusion... View Details
Keywords:
Science-Based Business;
Engineering;
Venture Capital;
Entrepreneurship;
Government and Politics;
Government Legislation;
Industry Clusters;
Industry Growth;
Industry Structures;
Technological Innovation;
Energy Industry;
United States
Krieger, Joshua Lev, Jim Matheson, Kyle R. Myers, and Henry Tao. "Fusion Industry Association: Igniting the Future of Clean Energy." Harvard Business School Case 624-064, January 2024.
- February 2024 (Revised March 2024)
- Teaching Note
X: The Foghorn Decision
By: Kyle Myers and Walter Frick
Teaching Note for HBS Case No. 618-060.
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Keywords:
Alternative Energy;
Energy Generation;
Energy Sources;
Climate Change;
Green Technology;
Selection and Staffing;
Knowledge;
Product Design;
Product Development;
Research and Development;
Risk and Uncertainty;
Science-Based Business;
Innovation and Invention;
Auto Industry;
Biotechnology Industry;
Chemical Industry;
Computer Industry;
Electronics Industry;
Green Technology Industry;
Technology Industry
- March 2024
- Case
Biomanufacturing Decentralization by Stämm
By: Paul A. Gompers, Jenyfeer Martínez Buitrago and Mariana Cal
In Buenos Aires, Argentina, cousins Llamazares and D’Alvia founded Stämm, a startup based on the idea of decentralizing biomanufacturing processes and downsizing biotech facilities. After raising its seed and series A rounds, and while finalizing its series B round in...
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Keywords:
Business Model;
Business Startups;
Entrepreneurship;
Venture Capital;
Selection and Staffing;
Technological Innovation;
Science-Based Business;
Business Strategy;
Commercialization;
Growth and Development Strategy;
Product Launch;
Research and Development;
Biotechnology Industry;
Latin America;
South America;
Argentina;
Buenos Aires
- 01 Jun 2017
- News
Alumni and Faculty Books for June 2017
demonstrate the solidity of France’s business ecosystem and the extraordinary opportunity of being an entrepreneur there. A Song of Humanity: A Science-Based Alternative to the World’s Scriptures by Only One Man (i.e., Jim Clawson, DBA...
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- January 2013
- Supplement
Cabot Corporation: The Fuel Cell Decision (B)
By: Willy Shih and Ying Zhou
Managers at Cabot Corporation are faced with deciding the future of its fuel cell program. The (A) case recounts the view of the business manager and the technical project lead, and the (B) case describes the perspective of a senior manager who is the head of the New...
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Keywords:
Technical Decision-making;
Decision Making Process;
Fuel Cells;
Decision Choices and Conditions;
Decisions;
Judgments;
Business Plan;
Business Exit or Shutdown;
Energy Generation;
Energy Sources;
Innovation and Management;
Innovation Strategy;
Technological Innovation;
Research and Development;
Science-Based Business;
Commercialization;
Technology Industry;
Manufacturing Industry;
United States;
Massachusetts
Shih, Willy, and Ying Zhou. "Cabot Corporation: The Fuel Cell Decision (B)." Harvard Business School Supplement 613-067, January 2013.
- September 1993 (Revised October 1994)
- Case
Environment and International Trade
During the 1990s, environmental activists became interested in trade issues for the first time. Whereas GATT, the General Agreement on Tariffs and Trade, had previously been the province of trade specialists, a new poster popular among environmentalists depicted the...
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Keywords:
Trade;
Environmental Sustainability;
Science-Based Business;
Policy;
Government and Politics;
Agreements and Arrangements;
Alliances;
Globalization;
International Relations;
Conflict of Interests
Reinhardt, Forest L. "Environment and International Trade." Harvard Business School Case 794-018, September 1993. (Revised October 1994.)
- July 2013 (Revised November 2021)
- Module Note
Exploration vs. Exploitation
By: Willy Shih
This module note introduces James March's concept of exploration and exploitation, and the management challenge of balancing the allocation of resources to the two activities in the firm. The note also touches on the O'Reilly and Tushman paper on the ambidextrous...
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Keywords:
Exploration And Exploitation;
Exploitation;
Research;
Scientific Research;
Product Commercialization;
Innovation and Invention;
Innovation and Management;
Innovation Leadership;
Innovation Strategy;
Technological Innovation;
Knowledge Acquisition;
Growth and Development Strategy;
Resource Allocation;
Strategic Planning;
Research and Development;
Science-Based Business;
Corporate Strategy;
Knowledge Sharing;
Biotechnology Industry;
Information Technology Industry;
Manufacturing Industry;
Medical Devices and Supplies Industry;
Pharmaceutical Industry;
Semiconductor Industry;
Technology Industry;
United States
Shih, Willy. "Exploration vs. Exploitation." Harvard Business School Module Note 614-004, July 2013. (Revised November 2021.)