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- 2024
- Working Paper
Does the Case for Private Equity Still Hold?
By: Nori Gerardo Lietz and Philipp Chvanov
Private Equity (“PE”) received a 10-fold increase in capital flows since the Great Financial Crisis (“GFC”) Investors sought higher nominal returns relative to those they could obtain in the public capital markets. This paper questions the fundamental assumptions...
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Lietz, Nori Gerardo, and Philipp Chvanov. "Does the Case for Private Equity Still Hold?" Harvard Business School Working Paper, No. 24-066, January 2024.
- April 2024
- Article
An Integrative Model of Hybrid Governance: The Role of Boards in Helping Sustain Organizational Hybridity
By: Anne-Claire Pache, Julie Battilana and Channing Spencer
Hybrid organizations must sustainably attend to multiple goals embedded in different institutional spheres. Past research has highlighted the value for hybrids in recruiting board members representing different logics to avoid attentional drifts; yet, diverse boards...
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Pache, Anne-Claire, Julie Battilana, and Channing Spencer. "An Integrative Model of Hybrid Governance: The Role of Boards in Helping Sustain Organizational Hybridity." Academy of Management Journal 67, no. 2 (April 2024): 437–467.
- 2023
- Working Paper
An Experimental Design for Anytime-Valid Causal Inference on Multi-Armed Bandits
By: Biyonka Liang and Iavor I. Bojinov
Typically, multi-armed bandit (MAB) experiments are analyzed at the end of the study and thus require the analyst to specify a fixed sample size in advance. However, in many online learning applications, it is advantageous to continuously produce inference on the...
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Liang, Biyonka, and Iavor I. Bojinov. "An Experimental Design for Anytime-Valid Causal Inference on Multi-Armed Bandits." Harvard Business School Working Paper, No. 24-057, March 2024.
- 2024
- Working Paper
Anytime-Valid Inference in Linear Models and Regression-Adjusted Causal Inference
By: Michael Lindon, Dae Woong Ham, Martin Tingley and Iavor I. Bojinov
Linear regression adjustment is commonly used to analyze randomized controlled experiments due to its efficiency and robustness against model misspecification. Current testing and interval estimation procedures leverage the asymptotic distribution of such estimators to...
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Lindon, Michael, Dae Woong Ham, Martin Tingley, and Iavor I. Bojinov. "Anytime-Valid Inference in Linear Models and Regression-Adjusted Causal Inference." Harvard Business School Working Paper, No. 24-060, March 2024.
- 2023
- Working Paper
Design-Based Inference for Multi-arm Bandits
By: Dae Woong Ham, Iavor I. Bojinov, Michael Lindon and Martin Tingley
Multi-arm bandits are gaining popularity as they enable real-world sequential decision-making across application areas, including clinical trials, recommender systems, and online decision-making. Consequently, there is an increased desire to use the available...
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Ham, Dae Woong, Iavor I. Bojinov, Michael Lindon, and Martin Tingley. "Design-Based Inference for Multi-arm Bandits." Harvard Business School Working Paper, No. 24-056, March 2024.
- February 2024 (Revised March 2024)
- Teaching Note
X: The Foghorn Decision
By: Kyle Myers and Walter Frick
Teaching Note for HBS Case No. 618-060.
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Keywords:
Alternative Energy;
Energy Generation;
Energy Sources;
Climate Change;
Green Technology;
Selection and Staffing;
Knowledge;
Product Design;
Product Development;
Research and Development;
Risk and Uncertainty;
Science-Based Business;
Innovation and Invention;
Auto Industry;
Biotechnology Industry;
Chemical Industry;
Computer Industry;
Electronics Industry;
Green Technology Industry;
Technology Industry
- February 2024
- Case
Compass Pathways: Pioneering Psychedelic Treatment
By: Tiona Zuzul, Kisha Lashley and Gamze Yucaoglu
This case follows Compass Pathways, a pioneering company developing treatment for depression based on psilocybin, the compound found in ‘magic mushrooms.’ Psilocybin was a federally illegal substance in the U.S., and a “Schedule I” drug, defined as a drug “with no...
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Keywords:
Commercialization;
Corporate Strategy;
Competitive Strategy;
Product Launch;
Health Testing and Trials;
Research and Development;
Laws and Statutes;
Pharmaceutical Industry;
Europe;
United States;
United Kingdom
Zuzul, Tiona, Kisha Lashley, and Gamze Yucaoglu. "Compass Pathways: Pioneering Psychedelic Treatment." Harvard Business School Case 724-412, February 2024.
- February 2024
- Article
Fifty Shades of QE: Robust Evidence
By: Brian Fabo, Marina Jančoková, Elisabeth Kempf and Ľuboš Pástor
Fabo et al. (2021) show that papers written by central bank researchers find quantitative easing (QE) to be more effective than papers written by academics. Weale and Wieladek (2022) show that a subset of these results lose statistical significance when OLS regressions...
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Keywords:
Quantitative Easing;
Research;
Mathematical Methods;
Perception;
Banks and Banking;
Body of Literature
Fabo, Brian, Marina Jančoková, Elisabeth Kempf, and Ľuboš Pástor. "Fifty Shades of QE: Robust Evidence." Art. 107065. Journal of Banking & Finance 159 (February 2024).
- February 2024 (Revised May 2024)
- Case
Moving Science: The Rowland Institute at Harvard
By: Maria P. Roche
Set in 2022, this case describes the considerations involved in organizing the physical relocation of the Rowland Institute at Harvard (RIH), a research institute established in 1980 by Edwin H. Land, the founder of the Polaroid Corporation, for the advancement of...
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Roche, Maria P. "Moving Science: The Rowland Institute at Harvard." Harvard Business School Case 724-441, February 2024. (Revised May 2024.)
- January 2024 (Revised April 2024)
- Case
Target Malaria: Editing Mosquitoes through Gene Drives
By: Shikhar Ghosh and Shweta Bagai
Target Malaria, a non-profit research consortium, is exploring the application of CRISPR-Cas9 gene editing technology to combat malaria in Sub-Saharan Africa. Its approach uses gene drives, a revolutionary tool, to suppress the population of malaria-carrying...
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Ghosh, Shikhar, and Shweta Bagai. "Target Malaria: Editing Mosquitoes through Gene Drives." Harvard Business School Case 824-068, January 2024. (Revised April 2024.)
- 2024
- Working Paper
Bootstrap Diagnostics for Irregular Estimators
By: Isaiah Andrews and Jesse M. Shapiro
Empirical researchers frequently rely on normal approximations in order to summarize and communicate uncertainty about their findings to their scientific audience. When such approximations are unreliable, they can lead the audience to make misguided decisions. We...
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Andrews, Isaiah, and Jesse M. Shapiro. "Bootstrap Diagnostics for Irregular Estimators." NBER Working Paper Series, No. 32038, January 2024.
- January 2024
- Article
Subset Scanning for Multi-Trait Analysis Using GWAS Summary Statistics
By: Rui Cao, Evan Olawsky, Edward McFowland III, Erin Marcotte, Logan Spector and Tianzhong Yang
Multi-trait analysis has been shown to have greater statistical power than single-trait analysis. Most of the existing multi-trait analysis methods only work with a limited number of traits and usually prioritize high statistical power over identifying relevant traits,...
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Cao, Rui, Evan Olawsky, Edward McFowland III, Erin Marcotte, Logan Spector, and Tianzhong Yang. "Subset Scanning for Multi-Trait Analysis Using GWAS Summary Statistics." Bioinformatics 40, no. 1 (January 2024).
- December 2023
- Teaching Note
Viceroy Research versus Medical Properties Trust
By: Jonas Heese and Joseph Pacelli
Teaching Note for HBS Case No. 124-027.
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- 2023
- Article
Balancing Risk and Reward: An Automated Phased Release Strategy
By: Yufan Li, Jialiang Mao and Iavor Bojinov
Phased releases are a common strategy in the technology industry for gradually releasing new products or updates through a sequence of A/B tests in which the number of treated units gradually grows until full deployment or deprecation. Performing phased releases in a...
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Li, Yufan, Jialiang Mao, and Iavor Bojinov. "Balancing Risk and Reward: An Automated Phased Release Strategy." Advances in Neural Information Processing Systems (NeurIPS) (2023).
- 2023
- Article
Dynamic HTA for Digital Health Solutions: Opportunities and Challenges for Patient-Centered Evaluation
By: Jan B. Brönneke, Annika Herr, Simon Reif and Ariel D. Stern
Germany’s 2019 Digital Healthcare Act (Digitale-Versorgung-Gesetz, or DVG) created a number of opportunities for the digital transformation of the health care delivery system. Key among these was the creation of a reimbursement pathway for patient-centered digital...
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Keywords:
Digital Transformation;
Applications and Software;
Product Development;
Insurance;
Policy;
Health Industry;
Germany
Brönneke, Jan B., Annika Herr, Simon Reif, and Ariel D. Stern. "Dynamic HTA for Digital Health Solutions: Opportunities and Challenges for Patient-Centered Evaluation." International Journal of Technology Assessment in Health Care 39, no. 1 (2023).
- 2023
- Article
Post Hoc Explanations of Language Models Can Improve Language Models
By: Satyapriya Krishna, Jiaqi Ma, Dylan Slack, Asma Ghandeharioun, Sameer Singh and Himabindu Lakkaraju
Large Language Models (LLMs) have demonstrated remarkable capabilities in performing complex tasks. Moreover, recent research has shown that incorporating human-annotated rationales (e.g., Chain-of-Thought prompting) during in-context learning can significantly enhance...
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Krishna, Satyapriya, Jiaqi Ma, Dylan Slack, Asma Ghandeharioun, Sameer Singh, and Himabindu Lakkaraju. "Post Hoc Explanations of Language Models Can Improve Language Models." Advances in Neural Information Processing Systems (NeurIPS) (2023).
- 2023
- Other Article
The Harvard USPTO Patent Dataset: A Large-Scale, Well-Structured, and Multi-Purpose Corpus of Patent Applications
By: Mirac Suzgun, Luke Melas-Kyriazi, Suproteem K. Sarkar, Scott Duke Kominers and Stuart Shieber
Innovation is a major driver of economic and social development, and information about many kinds of innovation is embedded in semi-structured data from patents and patent applications. Though the impact and novelty of innovations expressed in patent data are difficult...
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Keywords:
USPTO;
Natural Language Processing;
Classification;
Summarization;
Patent Novelty;
Patent Trolls;
Patent Enforceability;
Patents;
Innovation and Invention;
Intellectual Property;
AI and Machine Learning;
Analytics and Data Science
Suzgun, Mirac, Luke Melas-Kyriazi, Suproteem K. Sarkar, Scott Duke Kominers, and Stuart Shieber. "The Harvard USPTO Patent Dataset: A Large-Scale, Well-Structured, and Multi-Purpose Corpus of Patent Applications." Conference on Neural Information Processing Systems (NeurIPS), Datasets and Benchmarks Track 36 (2023).
- 2023
- Article
Verifiable Feature Attributions: A Bridge between Post Hoc Explainability and Inherent Interpretability
By: Usha Bhalla, Suraj Srinivas and Himabindu Lakkaraju
With the increased deployment of machine learning models in various real-world applications, researchers and practitioners alike have emphasized the need for explanations of model behaviour. To this end, two broad strategies have been outlined in prior literature to...
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Bhalla, Usha, Suraj Srinivas, and Himabindu Lakkaraju. "Verifiable Feature Attributions: A Bridge between Post Hoc Explainability and Inherent Interpretability." Advances in Neural Information Processing Systems (NeurIPS) (2023).
- 2023
- Article
Which Models Have Perceptually-Aligned Gradients? An Explanation via Off-Manifold Robustness
By: Suraj Srinivas, Sebastian Bordt and Himabindu Lakkaraju
One of the remarkable properties of robust computer vision models is that their input-gradients are often aligned with human perception, referred to in the literature as perceptually-aligned gradients (PAGs). Despite only being trained for classification, PAGs cause...
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Srinivas, Suraj, Sebastian Bordt, and Himabindu Lakkaraju. "Which Models Have Perceptually-Aligned Gradients? An Explanation via Off-Manifold Robustness." Advances in Neural Information Processing Systems (NeurIPS) (2023).
- October 2023
- Teaching Note
Timnit Gebru: 'SILENCED No More' on AI Bias and The Harms of Large Language Models
By: Tsedal Neeley and Tim Englehart
Teaching Note for HBS Case No. 422-085. Dr. Timnit Gebru—a leading artificial intelligence (AI) computer scientist and co-lead of Google’s Ethical AI team—was messaging with one of her colleagues when she saw the words: “Did you resign?? Megan sent an email saying that...
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