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- November 2009 (Revised March 2010)
- Case
Managing Drugs on the Forefront of Personalized Medicine: The Erbitux and Vectibix Story
By: Richard G. Hamermesh, Raju Kucherlapati and Rachel Gordon
In May 2007, Amgen Inc. (Amgen) received disappointing news from the European Medicines Agency (EMEA) that its drug Vectibix, developed to fight metastatic colorectal cancer, had been rejected. This was especially surprising news given that a similar rival drug had...
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Keywords:
Entrepreneurship;
Governing Rules, Regulations, and Reforms;
Health Testing and Trials;
Marketing Strategy;
Product Positioning;
Genetics;
Biotechnology Industry;
Europe;
United States
Hamermesh, Richard G., Raju Kucherlapati, and Rachel Gordon. "Managing Drugs on the Forefront of Personalized Medicine: The Erbitux and Vectibix Story." Harvard Business School Case 810-066, November 2009. (Revised March 2010.)
- October 2008
- Case
Diagnostic Genomics
By: Regina E. Herzlinger and Mark P. Allyn
Should this gene detection firm enter the business of providing tests for the detection of genetic diseases? If so, how should it prioritize the tests it could develop?
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Keywords:
Health Testing and Trials;
Market Entry and Exit;
Product Development;
Genetics;
Strategy;
Health Industry;
Medical Devices and Supplies Industry
Herzlinger, Regina E., and Mark P. Allyn. "Diagnostic Genomics." Harvard Business School Case 309-040, October 2008.
- February 2006 (Revised August 2006)
- Case
deCODE Genetics: Hunting for Genes to Develop Drugs
By: Debora L. Spar
In 1996, Kari Stefansson launched a new kind of biotechnology company and a whole new way of attacking diseases. Based in Iceland, his firm, deCODE Genetics, plans to identify the individual genetic markers that lead to society's most prevalent diseases. To do so, it...
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Keywords:
Information;
Innovation Strategy;
Genetics;
Ethics;
Health Disorders;
Biotechnology Industry;
Iceland
Spar, Debora L., and Chris Bebenek. "deCODE Genetics: Hunting for Genes to Develop Drugs." Harvard Business School Case 706-040, February 2006. (Revised August 2006.)
- 2003
- Other Unpublished Work
Short Selling in Practice--Intermediating Uncertain Share Availability
By: Gene M D'Avolio and André Perold
- June 2003 (Revised March 2008)
- Case
Schering-Plough and Genome Therapeutics: Discovering an Asthma Gene
By: Regina E. Herzlinger and Marc Aquino
Personalized medicine requires the identification of mutated genes. Schering-Plough's search for the one related to asthma requires finding families with the disease. Examines the industry that helps conduct such research, including contract research organizations.
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Keywords:
Health Disorders;
Research and Development;
Genetics;
Biotechnology Industry;
Pharmaceutical Industry
Herzlinger, Regina E., and Marc Aquino. "Schering-Plough and Genome Therapeutics: Discovering an Asthma Gene." Harvard Business School Case 303-044, June 2003. (Revised March 2008.)
- October 1998 (Revised December 1999)
- Case
Gene Research, the Mapping of Life and the Global Economy
By: Ray A. Goldberg and Juan Enriquez-Cabot
A new firm is being created to speed up the process of mapping humans, animals, and plants by combining gene technology with rapid gene identification to improve the health and well being of the human population and the productivity of crops and animals. How does one...
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Keywords:
Information Technology;
Organizational Structure;
Technological Innovation;
Business Processes;
Health Care and Treatment;
Performance Productivity;
Welfare;
Agribusiness;
Genetics;
Science-Based Business;
Biotechnology Industry;
Agriculture and Agribusiness Industry
Goldberg, Ray A., and Juan Enriquez-Cabot. "Gene Research, the Mapping of Life and the Global Economy." Harvard Business School Case 599-016, October 1998. (Revised December 1999.)
- 1970
- Book
Organizational Structure and Design
By: Gene W. Dalton, Paul R. Lawrence and J. W. Lorsch
Dalton, Gene W., Paul R. Lawrence and J. W. Lorsch, eds. Organizational Structure and Design. Homewood, IL: Richard D. Irwin, 1970.