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- 2011
- Article
Scalable Detection of Anomalous Patterns With Connectivity Constraints
By: Skyler Speakman, Edward McFowland III and Daniel B. Neill
We present GraphScan, a novel method for detecting arbitrarily shaped connected clusters in graph or network data. Given a graph structure, data observed at each node, and a score function defining the anomalousness of a set of nodes, GraphScan can efficiently and...
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- 2015
- Article
Scalable Detection of Anomalous Patterns With Connectivity Constraints
By: Skyler Speakman, Edward McFowland III and Daniel B. Neill
We present GraphScan, a novel method for detecting arbitrarily shaped connected clusters in graph or network data. Given a graph structure, data observed at each node, and a score function defining the anomalousness of a set of nodes, GraphScan can efficiently and...
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Speakman, Skyler, Edward McFowland III, and Daniel B. Neill. "Scalable Detection of Anomalous Patterns With Connectivity Constraints." Journal of Computational and Graphical Statistics 24, no. 4 (2015): 1014–1033.
- Article
Fast Subset Scan for Multivariate Spatial Biosurveillance
By: Daniel B. Neill, Edward McFowland III and Huanian Zheng
We present new subset scan methods for multivariate event detection in massive space-time datasets. We extend the recently proposed 'fast subset scan' framework from univariate to multivariate data, enabling computationally efficient detection of irregular space-time...
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Neill, Daniel B., Edward McFowland III, and Huanian Zheng. "Fast Subset Scan for Multivariate Spatial Biosurveillance." Statistics in Medicine 32, no. 13 (June 15, 2013): 2185–2208.
- November–December 2015
- Article
Active Postmarketing Drug Surveillance for Multiple Adverse Events
By: Joel Goh, Margrét V. Bjarnadóttir, Mohsen Bayati and Stefanos A. Zenios
Postmarketing drug surveillance is the process of monitoring the adverse events of pharmaceutical or medical devices after they are approved by the appropriate regulatory authorities. Historically, such surveillance was based on voluntary reports by medical...
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Keywords:
Drug Surveillance;
Health Care;
Stochastic Models;
Queueing;
Diffusion Approximation;
Brownian Motion;
Health Care and Treatment;
Analytics and Data Science;
Analysis
Goh, Joel, Margrét V. Bjarnadóttir, Mohsen Bayati, and Stefanos A. Zenios. "Active Postmarketing Drug Surveillance for Multiple Adverse Events." Operations Research 63, no. 6 (November–December 2015): 1528–1546. (Finalist, 2012 INFORMS Health Applications Society Pierskalla Award.)
- 2016
- Article
Penalized Fast Subset Scanning
By: Skyler Speakman, Sriram Somanchi, Edward McFowland III and Daniel B. Neill
We present the penalized fast subset scan (PFSS), a new and general framework for scalable and accurate pattern detection. PFSS enables exact and efficient identification of the most anomalous subsets of the data, as measured by a likelihood ratio scan statistic....
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Keywords:
Disease Surveillance;
Likelihood Ratio Statistic;
Pattern Detection;
Scan Statistic;
Mathematical Methods
Speakman, Skyler, Sriram Somanchi, Edward McFowland III, and Daniel B. Neill. "Penalized Fast Subset Scanning." Journal of Computational and Graphical Statistics 25, no. 2 (2016): 382–404. (Selected for “Best of JCGS” invited session by the journal’s editor in chief.)
- September 1986 (Revised February 1991)
- Case
Graves Industries, Inc. (C): Consumer Hardware Division
Describes events occurring over a three-year period in a division of Graves Industries. The division is being squeezed for profit, and managers in the division get involved in some fraudulent financial reporting schemes involving revenues and capitalization of...
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Merchant, Kenneth A. "Graves Industries, Inc. (C): Consumer Hardware Division." Harvard Business School Case 187-047, September 1986. (Revised February 1991.)
- September 1986 (Revised March 1987)
- Case
Graves Industries, Inc. (B): Lohnes Marine Hardware Division
Describes events occurring over a four-year period in one division of Graves Industries. The division goes through a business cycle and uses several methods of managing earnings to meet its budget targets. The purpose of the case is to allow the exploration of the...
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Merchant, Kenneth A. "Graves Industries, Inc. (B): Lohnes Marine Hardware Division." Harvard Business School Case 187-046, September 1986. (Revised March 1987.)
- 2022
- Working Paper
Post-market Surveillance of Software Medical Devices: Evidence from Regulatory Data
By: Alexander O. Everhart and Ariel D. Stern
Medical devices increasingly include software components, which facilitate remote patient monitoring. The introduction of software into previously analog medical devices as well as innovation in software-driven devices may introduce new safety concerns—all the more so...
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Keywords:
Technological Innovation;
Safety;
Governing Rules, Regulations, and Reforms;
Health Care and Treatment;
Medical Devices and Supplies Industry
Everhart, Alexander O., and Ariel D. Stern. "Post-market Surveillance of Software Medical Devices: Evidence from Regulatory Data." Harvard Business School Working Paper, No. 23-035, November 2022.
- 27 Jan 2020
- Research & Ideas
Hard Work Isn't Enough: How to Find Your Edge
Evidently the professor detected none of her sarcasm and gave her a B-minus. Huang avoided the mistake many people make: counting themselves out of the running based on the constraints other people place on them—or ones they place on...
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by Dina Gerdeman
- 06 Apr 2010
- First Look
First Look: April 6
methodologies for detecting "tunneling," or efforts by firms' controlling owner managers to take money for themselves at the expense of minority shareholders. We find that, in contrast to prior views, Indian business groups are...
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Keywords:
Martha Lagace
- 20 Dec 2011
- First Look
First Look: December 20
technological development offered by the Royal Agricultural Society of England at annual competitions between 1839 and 1939. We find that the effects of prizes on competitive entry are large, and we also detect an impact of the prizes on...
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Keywords:
Carmen Nobel
- 05 Dec 2012
- What Do You Think?
Should Managers Bother Listening to Predictions?
predictors. Taleb, in The Black Swan, worried that cataclysmic events (Sandy) are next to impossible to predict and too costly to prepare for, given the small probability that they will ever occur. Human beings by and large do not have...
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by James Heskett
- 24 Feb 2009
- First Look
First Look: February 24, 2009
complete, and advertisers can extend this delay both to improve detection of improper partner practices and to punish partners who turn out to be rule-breakers. I capture these relationships in a screening model with delayed payments and...
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Keywords:
Martha Lagace
- 21 Nov 2006
- First Look
First Look: November 21, 2006
meanness level that a penal system based on "retribution" tries to detect when deciding the severity of the punishment. We find that when initial beliefs differ, two equilibria can emerge out of identical fundamentals. In the...
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Keywords:
Sean Silverthorne
- 05 Nov 2014
- What Do You Think?
Are We Entering an Era of Neuromanagement?
by high levels of ambition and values or leadership behaviors at companies." Johnny added, "Neuromanagement will be based on electronic testing however it will not detect 'will-power.' It is our will that determines how...
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by James Heskett
- 09 Mar 2010
- First Look
First Look: March 9
legal event as a natural experiment to examine equity-debt conflicts in the vicinity of financial distress. A 1991 Delaware bankruptcy ruling changed the nature of corporate directors' fiduciary duties in that state. This change limited...
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Keywords:
Martha Lagace
- 12 Jan 2016
- First Look
January 12, 2016
and minimizes the expected time to detection under a pre-specified alternative hypothesis. We apply our method to a model in which the interdependency among the multiple adverse events is captured by a Cox...
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Carmen Nobel
- 14 Aug 2007
- First Look
First Look: August 14, 2007
activism are high for the subset of targets that are acquired ex-post, but not detectably different from zero for targets that remain independent a year after the initial activist request. Announcement returns show a similar pattern....
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Martha Lagace
- 25 Jul 2006
- First Look
First Look: July 25, 2006
and other government entities to detect and deter such attacks. Explores why complex organizations with multiple missions develop seams and become vulnerable to threats that cut across those seams. Fuels a discussion of whether and how...
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Keywords:
Sean Silverthorne
- 15 Jul 2002
- Research & Ideas
Going Green Makes Good Business Sense
living longer—but eventually dying of diseases that could plausibly have an environmental component. Just as there has been progress in scientifically detecting foreign contaminants in the air and water, the public clamors for protection...
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Keywords:
by Martha Lagace