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- November 2016 (Revised December 2016)
- Supplement
Anthony Starks at InSiL Therapeutics (B)
By: Vicki Sato and Gary Pisano
This case accompanies the (A) case from Anthony Starks's perspective.
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Keywords:
Biotech;
Management Challenges;
R&D;
R&D Project Management;
Management;
Biotechnology Industry;
California
Sato, Vicki, and Gary Pisano. "Anthony Starks at InSiL Therapeutics (B)." Harvard Business School Supplement 617-030, November 2016. (Revised December 2016.)
- November 2016
- Case
QuintilesIMS: Biosimilar Marketing in England
By: John A. Quelch and Emily C. Boudreau
QuintilesIMS was a leading healthcare consulting firm best known for its data and information offerings as well as its market research and management consulting services for life science companies. By 2015, the company was expanding beyond the biopharmaceutical...
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Keywords:
Health;
Pharmaceutical Industry;
Biotech;
Marketing;
Health Care and Treatment;
Biotechnology Industry;
England
Quelch, John A., and Emily C. Boudreau. "QuintilesIMS: Biosimilar Marketing in England." Harvard Business School Case 517-054, November 2016.
- October 2016 (Revised September 2017)
- Case
The CRISPR-Cas9 Quarrel
By: Richard G. Hamermesh and Matthew G. Preble
In mid-2016, the Broad Institute and the University of California, Berkeley were in the middle of a contentious patent dispute over which entity controlled a breakthrough gene editing technology called CRISPR-Cas9. With CRISPR-Cas9, scientists might soon be able to...
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Keywords:
CRISPR;
Broad Institute;
University Of California Berkeley;
Intellectual Property;
Patents;
Law;
Lawsuits and Litigation;
Science;
Genetics;
Entrepreneurship;
Biotechnology Industry;
United States
Hamermesh, Richard G., and Matthew G. Preble. "The CRISPR-Cas9 Quarrel." Harvard Business School Case 817-020, October 2016. (Revised September 2017.)
- October 2016 (Revised February 2017)
- Teaching Note
Alvogen
By: Daniel Isenberg, William R. Kerr and Alexis Brownell
Alvogen is an Icelandic pharmaceutical company that makes and sells generic drugs. Founder and CEO Robert Wessman is deciding whether to take on private equity investors willing to buy out all shareholders, merge with a large and publicly-traded US pharmaceutical...
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- May 25, 2016
- Comment
How Consumers and Businesses are Reshaping Public Health
By: John A. Quelch
Healthcare and education are two issues in which citizens around the world, rich and poor, are passionately interested. It has long been appreciated that the way that a society treats its youngest and oldest members says much about its moral maturity. Economic...
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Keywords:
Healthcare;
Consumer Power;
Innovation In Healthcare Delivery;
Mobile Healthcare;
Transition;
Transformation;
Trends;
Customer Satisfaction;
Customer Value and Value Chain;
Health Care and Treatment;
Information;
Collaborative Innovation and Invention;
Independent Innovation and Invention;
Innovation and Management;
Innovation Leadership;
Management;
Marketing;
Markets;
Planning;
Problems and Challenges;
Biotechnology Industry;
Biotechnology Industry;
Biotechnology Industry;
Biotechnology Industry;
Biotechnology Industry;
Biotechnology Industry;
Biotechnology Industry;
Biotechnology Industry;
Biotechnology Industry;
Biotechnology Industry;
Biotechnology Industry;
Biotechnology Industry;
South America;
North and Central America;
Middle East;
Europe;
Asia
Quelch, John A. "How Consumers and Businesses are Reshaping Public Health." Harvard Business School Working Knowledge (May 25, 2016).
- May 20, 2016
- Comment
World Health Organization Lacks Leadership to Combat Pandemics
By: John A. Quelch
When it comes to emergency preparedness for pandemics, the World Health Organization is falling short. It has not provided prompt and clear leadership to the world in combating either the Ebola or Zika viruses. Its leadership has been low energy, its representatives...
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Keywords:
Global Health;
World Health Organization;
World Bank;
Pandemics;
Emergency Preparedness;
Experience and Expertise;
Decisions;
Forecasting and Prediction;
Communication Strategy;
Nonverbal Communication;
Framework;
Governance;
Government and Politics;
Health;
Management;
Practice;
Problems and Challenges;
Projects;
Risk and Uncertainty;
Human Needs;
Civil Society or Community;
Social Issues;
Welfare or Wellbeing;
Biotechnology Industry;
Biotechnology Industry;
Biotechnology Industry;
Biotechnology Industry;
Biotechnology Industry;
Biotechnology Industry;
Biotechnology Industry;
Biotechnology Industry;
Africa;
Asia;
Europe;
Latin America;
North and Central America;
South America;
West Indies
Quelch, John A. "World Health Organization Lacks Leadership to Combat Pandemics." Harvard Business School Working Knowledge (May 20, 2016).
- March 2016
- Article
Environmental Demands and the Emergence of Social Structure: Technological Dynamism and Interorganizational Network Forms
By: Adam Tatarynowicz, Maxim Sytch and Ranjay Gulati
This study investigates the origins of variation in the structures of interorganizational networks across industries. We combine empirical analyses of existing interorganizational networks in six industries with an agent-based simulation model of network emergence....
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Keywords:
Interorganizatonal Relationships;
Social Networks;
Network Emergence;
Interorganizational Networks;
Information Technology;
Networks;
Organizational Structure;
Social and Collaborative Networks;
Social Media
Tatarynowicz, Adam, Maxim Sytch, and Ranjay Gulati. "Environmental Demands and the Emergence of Social Structure: Technological Dynamism and Interorganizational Network Forms." Administrative Science Quarterly 61, no. 1 (March 2016): 52–86.
- January 2016 (Revised February 2016)
- Course Overview Note
The Sustainable Core: Operations Management
By: Michael W. Toffel and L. Beril Toktay
This note is designed to help faculty embed environmental sustainability content into their core Operations Management course at the MBA or undergraduate level. It can also be used to identify cases with environmental content that can be used in operations electives...
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Keywords:
Environmental Management;
Operations Management;
Sustainable Operations;
Environmental Regulation;
Operations;
Supply Chain;
Supply Chain Management;
Agriculture and Agribusiness Industry;
Agriculture and Agribusiness Industry;
Agriculture and Agribusiness Industry;
Agriculture and Agribusiness Industry;
Agriculture and Agribusiness Industry;
Agriculture and Agribusiness Industry
Toffel, Michael W., and L. Beril Toktay. "The Sustainable Core: Operations Management." Harvard Business School Course Overview Note 616-022, January 2016. (Revised February 2016.)
- 2016
- Book
Consumers, Corporations, and Public Health: A Case-Based Approach to Sustainable Business
By: John A. Quelch
The public health footprint associated with corporate behavior has come under increased scrutiny in the last decade, with an increased expectation that private profit not come at the expense of consumer welfare.
Consumers, Corporations, and Public... View Details
Consumers, Corporations, and Public... View Details
Keywords:
Consumer;
Corporate Culture;
Public Health;
Consumer Behavior;
Marketing Strategy;
Corporate Strategy;
Health;
Innovation and Invention;
Innovation and Management;
Supply Chain Management;
Advertising Industry;
Advertising Industry;
Advertising Industry;
Advertising Industry;
Advertising Industry;
Advertising Industry;
Advertising Industry;
Advertising Industry;
Advertising Industry;
Advertising Industry;
Advertising Industry;
Advertising Industry;
Advertising Industry;
Advertising Industry;
Advertising Industry;
Advertising Industry;
Advertising Industry;
Advertising Industry;
Advertising Industry;
Advertising Industry;
Advertising Industry;
Asia;
Oceania;
North and Central America;
Middle East;
Latin America;
Europe
Quelch, John A. Consumers, Corporations, and Public Health: A Case-Based Approach to Sustainable Business. New York: Oxford University Press, 2016.
- Article
What to Know About Locating in a Cluster
By: Willy C. Shih and Sen Chai
As a study of two industry clusters in Denmark shows, factors that can make clusters attractive—easy people movement and knowledge spillovers—can also make it harder for individual companies to retain proprietary knowledge.
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Keywords:
Clusters;
Clustering;
Competitiveness;
Life Sciences;
Telecommunications;
Science-based;
Research And Development;
Industry Clusters;
Research;
Innovation Strategy;
Innovation and Management;
Geographic Location;
Pharmaceutical Industry;
Pharmaceutical Industry;
Pharmaceutical Industry;
Pharmaceutical Industry;
Denmark
Shih, Willy C., and Sen Chai. "What to Know About Locating in a Cluster." Art. 57117. MIT Sloan Management Review 57, no. 1 (Fall 2015): 104–107.
- May 2015
- Case
Transforming Alkermes into a Global Biopharmaceutical Company
By: C. Fritz Foley and Nicholas Haas
In the summer of 2011, Jim Frates, CFO of Alkermes faced choices about how to finance the acquisition of Dublin, Ireland-based Elan Drug Technologies (EDT)—a deal that was expected to close in the fall. The case describes the history of Alkermes, provides information...
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Keywords:
Financing;
Debt;
Merger;
CFO;
Financial Management;
Biotechnology Industry;
Biotechnology Industry;
United States;
Europe
Foley, C. Fritz, and Nicholas Haas. "Transforming Alkermes into a Global Biopharmaceutical Company." Harvard Business School Case 215-079, May 2015.
- February 2015 (Revised November 2015)
- Supplement
Building an Integrated Biopharma Company: Crucell (B)
By: Richard G. Hamermesh, Marianne Van Der Steen and Susan Harmeling
The Crucell (B) case updates events at Crucell since 2009. In September, 2009, Johnson & Johnson acquired 18% of Crucell for $400 million. This investment was part of a business development deal. Subsequently, in 2012, Johnson & Johnson acquired Crucell for $2.8...
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Keywords:
Biotechnology;
Biopharmacy Company;
Licensing Agreements In Biopharmacy;
Licensing;
Human Cell-line Technology;
Vaccine;
Healthcare Innovation;
Global Health;
Entrepreneurship;
Health Care and Treatment;
Acquisition;
Innovation and Invention;
Biotechnology Industry;
Biotechnology Industry
Hamermesh, Richard G., Marianne Van Der Steen, and Susan Harmeling. "Building an Integrated Biopharma Company: Crucell (B)." Harvard Business School Supplement 815-086, February 2015. (Revised November 2015.)
- February 2015 (Revised November 2015)
- Case
Building an Integrated Biopharma Company: Crucell (A)
By: Richard G. Hamermesh, Marianne Van Der Steen and Susan S. Harmeling
By 2009, Crucell had become the largest biopharma company in the Netherlands and a symbol of national pride. The case traces the evolution of the company from a University spin-off into a fully-integrated company. Crucell's success, particularly in the vaccine space,...
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Keywords:
Biotechnology;
Biopharmacy Company;
Licensing;
Licensing Agreements In Biopharmacy;
Human Cell-line Technology;
Vaccine;
Healthcare Innovation;
Global Health;
Partners and Partnerships;
Entrepreneurship;
Growth and Development Strategy;
Biotechnology Industry;
Biotechnology Industry;
Netherlands
Hamermesh, Richard G., Marianne Van Der Steen, and Susan S. Harmeling. "Building an Integrated Biopharma Company: Crucell (A)." Harvard Business School Case 815-085, February 2015. (Revised November 2015.)
- September 2014
- Case
Pfizer's Centers for Therapeutic Innovation (CTI)
By: Gary Pisano, James Weber and Kait Szydlowski
In 2010, Pfizer established four small research units in New York, Boston, San Francisco, and San Diego located close to several premier Academic Medical Centers (AMCs), or hospitals with adjoining medical schools. The goal of these units was to redesign collaboration...
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Keywords:
Drug Development;
Academic Collaboration;
Research And Development;
Innovation;
Translational Research;
Management;
Operations;
Problems and Challenges;
Research;
Science;
Information Technology;
Strategy;
Biotechnology Industry;
Biotechnology Industry;
North and Central America;
Europe;
Asia
Pisano, Gary, James Weber, and Kait Szydlowski. "Pfizer's Centers for Therapeutic Innovation (CTI)." Harvard Business School Case 615-024, September 2014.
- July 2014 (Revised January 2017)
- Course Overview Note
Building Life Science Businesses Spring Term 2017: Course Outline and Syllabus
This Course Outline and Syllabus gives an overview of the Spring 2016 class Building Life Science Businesses.7
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Keywords:
Healthcare Ventures;
Entrepreneurial Management;
Entrepreneurship;
Entrepreneurs;
Health Care and Treatment;
Health Testing and Trials;
Medical Specialties;
Health Industry;
Health Industry;
Health Industry;
Asia;
North America;
Europe
Hamermesh, Richard G. "Building Life Science Businesses Spring Term 2017: Course Outline and Syllabus." Harvard Business School Course Overview Note 815-003, July 2014. (Revised January 2017.)
- June 2014
- Supplement
Merrimack Pharmaceuticals, Inc. (B)
By: Amy C. Edmondson, Bethany Gerstein and Melissa Valentine
In 2006, the leadership team at Merrimack Pharmaceuticals, Inc. had to decide whether to keep its R&D organization in functional departments or restructure it into interdisciplinary teams. This case follows the outcomes of this decision from 2006 to mid-2014, and...
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Keywords:
Organizational Design;
Groups and Teams;
Collaborative Innovation and Invention;
Research and Development;
Biotechnology Industry;
Biotechnology Industry
Edmondson, Amy C., Bethany Gerstein, and Melissa Valentine. "Merrimack Pharmaceuticals, Inc. (B)." Harvard Business School Supplement 614-083, June 2014.
- April 2014
- Case
Merrimack Pharmaceuticals, Inc. (A)
By: Amy C. Edmondson, Bethany S. Gerstein and Melissa Valentine
In 2006, Merrimack Pharmaceuticals was a fast-growing biotechnology company. Its leadership team was divided over whether to keep R&D organized in functional departments or transition to interdisciplinary teams. As a small company, Merrimack's R&D organization had...
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Keywords:
Teamwork;
Interdisciplinary Collaboration;
R&D;
Biotechnology;
Complexity;
Innovation Management;
Organizational Design;
Groups and Teams;
Collaborative Innovation and Invention;
Research and Development;
Biotechnology Industry;
Biotechnology Industry
Edmondson, Amy C., Bethany S. Gerstein, and Melissa Valentine. "Merrimack Pharmaceuticals, Inc. (A)." Harvard Business School Case 614-063, April 2014.
- Spring 2014
- Article
Attracting Long-Term Investors Through Integrated Thinking and Reporting: A Clinical Study of a Biopharmaceutical Company
By: Andrew Knauer and George Serafeim
Faced with a large percentage of investors that chase short-term returns, companies could benefit by attracting investors with longer-term horizons and incentives that are more consistent with the long-term strategy of the company. The managers of most companies take...
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Keywords:
Investing;
Asset Management;
Long-term Investing;
Short-termism;
Sustainability;
Integrated Reporting;
Leadership & Corporate Accountability;
Pharmaceuticals;
Leadership;
Integrated Corporate Reporting;
Investment;
Business and Stakeholder Relations;
Corporate Finance;
Biotechnology Industry;
Biotechnology Industry
Knauer, Andrew, and George Serafeim. "Attracting Long-Term Investors Through Integrated Thinking and Reporting: A Clinical Study of a Biopharmaceutical Company." Journal of Applied Corporate Finance 26, no. 2 (Spring 2014): 57–64.
- March 2014
- Module Note
Implementing Environmentally Sustainable Operations
Keywords:
Sustainability;
Sustainability Management;
Sustainability Reporting;
Sustainable Supply Chains;
Sustainable Operations;
Environment;
Environmental And Social Sustainability;
Environmental Management;
Environmental Operations;
Environmental Performance;
Environmental Policy;
Environmental Protection;
Environmental Strategy;
Environmental Regulation;
Operations Management;
Operations Strategy;
Supply Chain Management;
Operations;
Supply Chain;
Business Processes;
Corporate Social Responsibility and Impact;
Performance Evaluation;
Performance Improvement;
Safety;
Social Enterprise;
Quality;
Production;
Working Conditions;
Animal-Based Agribusiness;
Buildings and Facilities;
Agriculture and Agribusiness Industry;
Agriculture and Agribusiness Industry;
Agriculture and Agribusiness Industry;
Agriculture and Agribusiness Industry;
Agriculture and Agribusiness Industry
Toffel, Michael W. "Implementing Environmentally Sustainable Operations." Harvard Business School Module Note 613-090, March 2014.
- February 2014
- Case
BGI: Data-driven Research
By: Willy Shih and Sen Chai
BGI has the largest installed gene-sequencing capacity in the world, and to Zhang Gengyun, general manager of the Life Sciences Division, this represented an opportunity to apply his training as a plant breeder and his early career work as a biochemist to improving...
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Keywords:
Genomics;
Gene Sequencing;
Life Sciences;
Plant Breeding;
Human Genome Program;
Beijing Genomics Institute;
BGI;
Rice Genome;
Technological Innovation;
Innovation Strategy;
Research;
Research and Development;
Science;
Genetics;
Science-Based Business;
Strategy;
Commercialization;
Corporate Strategy;
Information Technology;
Applications and Software;
Agriculture and Agribusiness Industry;
Agriculture and Agribusiness Industry;
Agriculture and Agribusiness Industry;
China;
United States
Shih, Willy, and Sen Chai. "BGI: Data-driven Research." Harvard Business School Case 614-056, February 2014.