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- 2024
- Working Paper
Dusting Off the Old Ones: Drug Licensing to Startups, Innovation Success and Efficiency
By: Mosab Hammoudeh, Joshua Lev Krieger and Jiajie Xu
This paper investigates whether moving R&D from incumbents to startups can increase innovation. Using comprehensive drug development data, we examine the outcomes of drug projects licensed from large firms to startups. We find that these projects licensed to startups...
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Keywords:
Product Development;
Innovation and Invention;
Business Startups;
Research and Development;
Performance Efficiency;
Pharmaceutical Industry
Hammoudeh, Mosab, Joshua Lev Krieger, and Jiajie Xu. "Dusting Off the Old Ones: Drug Licensing to Startups, Innovation Success and Efficiency." Harvard Business School Working Paper, No. 24-067, March 2024.
- 2023
- Working Paper
Estimating Productivity in the Presence of Spillovers: Firm-Level Evidence from the U.S. Production Network
By: Ebehi Iyoha
This paper examines the extent to which productivity gains are transmitted across U.S. firms through buyer-supplier relationships. Many empirical studies measure firm-to-firm spillovers using firm-level productivity estimates derived from control function approaches....
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Iyoha, Ebehi. "Estimating Productivity in the Presence of Spillovers: Firm-Level Evidence from the U.S. Production Network." Harvard Business School Working Paper, No. 24-033, December 2023. (Winner of the Young Economists' Essay Award at the 2021 Annual Conference of the European Association for Research in Industrial Economics (EARIE))
- December 2023
- Article
What Can Stockouts Tell Us About Inflation? Evidence from Online Micro Data
By: Alberto Cavallo and Oleksiy Kryvtsov
We use a detailed micro dataset on product availability and stockouts to construct a direct high-frequency measure of consumer product shortages during the 2020-2022 pandemic. We document a widespread multi-fold rise in stockouts in nearly all sectors early in the...
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Keywords:
Prices;
Stockouts;
Inventories;
Supply Disruptions;
COVID-19 Pandemic;
Supply Chain;
Product;
Demand and Consumers
Cavallo, Alberto, and Oleksiy Kryvtsov. "What Can Stockouts Tell Us About Inflation? Evidence from Online Micro Data." Journal of International Economics 146 (December 2023).
- October 2023
- Article
Laboratory Safety and Research Productivity
By: Alberto Galasso, Hong Luo and Brooklynn Zhu
Are laboratory safety practices a tax on scientific productivity? We examine this question by exploiting the substantial increase in safety regulations at the University of California following the shocking accidental death of a research assistant in 2008....
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Keywords:
Economics Of Science;
Risk Perception;
Safety Regulations;
Governing Rules, Regulations, and Reforms;
Working Conditions;
Safety;
Performance Productivity
Galasso, Alberto, Hong Luo, and Brooklynn Zhu. "Laboratory Safety and Research Productivity." Art. 104827. Research Policy 52, no. 8 (October 2023).
- September 2022
- Article
Find and Replace: R&D Investment Following the Erosion of Existing Products
By: Joshua L. Krieger, Xuelin Li and Richard T. Thakor
How do innovative firms react when existing products experience negative shocks? We explore this question with detailed project-level data from drug development firms. Using FDA Public Health Advisories as idiosyncratic negative shocks to approved drugs, we first...
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Keywords:
R&D Investments;
Drug Development;
Product Shocks;
M&A;
Biopharmaceutical Industry;
FDA;
System Shocks;
Research and Development;
Investment;
Decision Making;
Pharmaceutical Industry
Krieger, Joshua L., Xuelin Li, and Richard T. Thakor. "Find and Replace: R&D Investment Following the Erosion of Existing Products." Management Science 68, no. 9 (September 2022): 6552–6571.
- 2023
- Working Paper
Dynamic Pricing, Intertemporal Spillovers, and Efficiency
By: Alexander J. MacKay, Dennis Svartbäck and Anders G. Ekholm
Pricing technology that allows firms to rapidly adjust prices has two potential benefits.
Time-varying prices can respond to high-frequency demand shocks to generate greater revenues,
and they can also be used to smooth out demand to reduce costs. Using data...
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MacKay, Alexander J., Dennis Svartbäck, and Anders G. Ekholm. "Dynamic Pricing, Intertemporal Spillovers, and Efficiency." Harvard Business School Working Paper, No. 23-007, July 2022. (Revised December 2023.)
- 2021
- Working Paper
Multi-location Workers in Multinational Firms? Tradeoffs in Contextual Specialization of Employees and Organizational Outcomes
We study how “contextual specialization,” the act of focusing workers’ organizational tasks within a particular locational context, and “contextual non-specialization,” the practice of diversifying workers’ organizational tasks among multiple locational contexts,...
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Keywords:
Talent and Talent Management;
Performance;
Experience and Expertise;
Selection and Staffing;
Strength and Weakness;
Personal Development and Career
Gibson, Hise O., Ryan W. Buell, and Prithwiraj Choudhury. "Multi-location Workers in Multinational Firms? Tradeoffs in Contextual Specialization of Employees and Organizational Outcomes." Harvard Business School Working Paper, No. 22-007, August 2021.
- February 2021
- Article
Do Household Wealth Shocks Affect Productivity? Evidence from Innovative Workers During the Great Recession
By: S. Bernstein, T. McQuade and R. Townsend
We investigate how the deterioration of household balance sheets affects worker productivity, and, in turn, economic downturns. Specifically, we compare the output of innovative workers who experienced differential declines in housing wealth during the financial crisis...
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Keywords:
Great Recession;
Household;
Financial Condition;
System Shocks;
Employees;
Performance Productivity
Bernstein, S., T. McQuade, and R. Townsend. "Do Household Wealth Shocks Affect Productivity? Evidence from Innovative Workers During the Great Recession." Journal of Finance 76, no. 1 (February 2021): 57–111.
- January 2021
- Article
Turbulence, Firm Decentralization and Growth in Bad Times
By: Philippe Aghion, Nicholas Bloom, Brian Lucking, Raffaella Sadun and John Van Reenen
What is the optimal form of firm organization during “bad times”? We present a model of delegation within the firm to show that the effect is ambiguous. The greater turbulence following macro shocks may benefit decentralized firms because the value of local information...
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Keywords:
Decentralization;
Growth;
Turbulence;
Great Recession;
Organizational Design;
System Shocks;
Economic Growth;
Performance
Aghion, Philippe, Nicholas Bloom, Brian Lucking, Raffaella Sadun, and John Van Reenen. "Turbulence, Firm Decentralization and Growth in Bad Times." American Economic Journal: Applied Economics 13, no. 1 (January 2021): 133–169.
- Article
Foreign Competition and Domestic Innovation: Evidence from U.S. Patents
By: David Autor, David Dorn, Gordon H. Hanson, Gary P. Pisano and Pian Shu
Manufacturing accounts for more than three-quarters of U.S. corporate patents. The competitive shock to this sector emanating from China's economic ascent could in theory either augment or stifle U.S. innovation. Using three decades of U.S. patents matched to corporate...
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Autor, David, David Dorn, Gordon H. Hanson, Gary P. Pisano, and Pian Shu. "Foreign Competition and Domestic Innovation: Evidence from U.S. Patents." American Economic Review: Insights 2, no. 3 (September 2020): 357–374.
- Summer 2020
- Article
Is It Time to Rethink Globalized Supply Chains?: The COVID-19 Pandemic Should Be a Wake-up Call for Managers and Prompt Them to Consider Actions That Will Improve Their Resilience to Future Shocks
By: Willy C. Shih
The COVID-19 pandemic has exposed the complex interdependencies of globalized supply chains. While these global multistage production networks had spread during a relatively benign environment of falling trade barriers and increasing interdependencies among countries,...
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Keywords:
Supply Chains;
Pandemic;
Resilience;
Supply Chain Management;
Supply Chain;
Global Range;
Health Pandemics;
Disruption;
System Shocks;
Crisis Management;
Manufacturing Industry;
United States;
Asia;
Europe;
China
Shih, Willy C. "Is It Time to Rethink Globalized Supply Chains? The COVID-19 Pandemic Should Be a Wake-up Call for Managers and Prompt Them to Consider Actions That Will Improve Their Resilience to Future Shocks." MIT Sloan Management Review 61, no. 4 (Summer 2020): 16–18.
- 2023
- Working Paper
Founder-CEO Compensation and Selection into Venture Capital-Backed Entrepreneurship
By: Michael Ewens, Ramana Nanda and Christopher Stanton
We show theoretically that a critical determinant of the attractiveness of VC-backed entrepreneurship for high-earning potential founders is the expected time to develop a startup’s initial product. This is because founder-CEOs’ cash compensation increases...
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Ewens, Michael, Ramana Nanda, and Christopher Stanton. "Founder-CEO Compensation and Selection into Venture Capital-Backed Entrepreneurship." Harvard Business School Working Paper, No. 20-119, May 2020. (Revised September 2023. Forthcoming at Journal of Finance.)
- Fall 2019
- Article
Endogenous Productivity of Demand-Induced R&D: Evidence from Pharmaceuticals
By: Kyle Myers and Mark Pauly
We examine trends in the productivity of the pharmaceutical sector over the past three decades. Motivated by Ricardo’s insight that productivity and rents are endogenous to demand when inputs are scarce, we examine the industry’s aggregate R&D production function....
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Keywords:
Innovation;
Productivity;
Pharmaceuticals;
Innovation and Invention;
Performance Productivity;
Pharmaceutical Industry
Myers, Kyle, and Mark Pauly. "Endogenous Productivity of Demand-Induced R&D: Evidence from Pharmaceuticals." RAND Journal of Economics 50, no. 3 (Fall 2019): 591–614.
- 2019
- Working Paper
The Effect of Payment Choices on Online Retail: Evidence from the 2016 Indian Demonetization
By: Chaithanya Bandi, Antonio Moreno, Donald Ngwe and Zhiji Xu
The Indian banknote demonetization in 2016 was one of the most significant international events of that year. Overnight, 86% of Indian currency in circulation was declared invalid unless exchanged for new bills. The sudden and unexpected demonetization constituted a...
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Keywords:
Cash On Delivery;
Online Retail;
Product Returns;
Payment Methods;
Digitization;
Emerging Markets;
Currency;
Internet and the Web;
Demand and Consumers;
Retail Industry;
India
Bandi, Chaithanya, Antonio Moreno, Donald Ngwe, and Zhiji Xu. "The Effect of Payment Choices on Online Retail: Evidence from the 2016 Indian Demonetization." Harvard Business School Working Paper, No. 19-123, June 2019.
- June 2019
- Case
The Shale Revolution: America's Energy Independence?
By: Richard H.K. Vietor and Howaida Kamel
The shale revolution has upended oil and gas markets for nearly a decade and has positioned the U.S. to become a net energy exporter by 2020. Technological improvements pushed productivity forward which has had positive overall positive affects for the U.S. economy....
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- 2019
- Working Paper
Government Technology Policy, Social Value, and National Competitiveness
By: Frank Nagle
This study seeks to better understand the impact that government technology procurement regulations have on social value and national competitiveness. To do this, it examines the impact of a change in France’s technology procurement policy that required government...
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Keywords:
Social Value;
Competitiveness;
Government Administration;
Information Technology;
Acquisition;
Policy;
Value
Nagle, Frank. "Government Technology Policy, Social Value, and National Competitiveness." Harvard Business School Working Paper, No. 19-103, March 2019.
- August 2018 (Revised August 2018)
- Case
The De Beers Group: Launching Lightbox Jewelry for Lab-Grown Diamonds
By: Benjamin C. Esty
In May 2018, the De Beers Group shocked the diamond industry when it announced it was launching a new fashion jewelry brand of laboratory-grown (synthetic) diamonds. The reaction was swift as people sought to understand the company’s motivations: was it a “huge gamble”...
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Keywords:
Diamonds;
Differentiation;
New Business;
Strategy Development;
Strategy Execution;
Scope;
Adjacency;
Core;
Commoditization;
New Product Launch;
Mining;
Retail;
Corporate Strategy;
Business Strategy;
Disruption;
Value Creation;
Product Launch;
Segmentation;
Expansion;
Competitive Advantage;
United States;
United Kingdom
Esty, Benjamin C. "The De Beers Group: Launching Lightbox Jewelry for Lab-Grown Diamonds." Harvard Business School Case 719-408, August 2018. (Revised August 2018.)
- 2016
- Working Paper
Foreign Competition and Domestic Innovation: Evidence from U.S. Patents
By: David Autor, David Dorn, Gordon H. Hanson, Pian Shu and Gary Pisano
Manufacturing is the locus of U.S. innovation, accounting for more than three quarters of U.S. corporate patents. The rise of import competition from China has represented a major competitive shock to the sector, which in theory could benefit or stifle innovation. In...
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Keywords:
Patents;
Competition;
System Shocks;
Trade;
Innovation and Invention;
Manufacturing Industry;
China;
United States
Autor, David, David Dorn, Gordon H. Hanson, Pian Shu, and Gary Pisano. "Foreign Competition and Domestic Innovation: Evidence from U.S. Patents." NBER Working Paper Series, No. 22879, December 2016.
- 2016
- Chapter
Networks and the Macroeconomy: An Empirical Exploration
By: Daron Acemoglu, Ufuk Akcigit and William R. Kerr
The propagation of macroeconomic shocks through input-output and geographic networks can be a powerful driver of macroeconomic fluctuations. We first exposit that in the presence of Cobb-Douglas production functions and consumer preferences, there is a specific pattern...
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Keywords:
Economic Fluctuations;
Geographic Collocation;
Input-output Linkages;
Propagation;
Shocks;
Networks;
Fluctuation;
System Shocks;
Macroeconomics
Acemoglu, Daron, Ufuk Akcigit, and William R. Kerr. "Networks and the Macroeconomy: An Empirical Exploration." In NBER Macroeconomics Annual 2015, Vol. 30, edited by Martin Eichenbaum and Jonathan Parker, 273–335. Chicago, IL: University of Chicago Press, 2016.
- 2015
- Working Paper
Networks and the Macroeconomy: An Empirical Exploration
By: Daron Acemoglu, Ufuk Akcigit and William Kerr
The propagation of macroeconomic shocks through input-output and geographic networks can be a powerful driver of macroeconomic fluctuations. We first exposit that in the presence of Cobb-Douglas production functions and consumer preferences there is a specific pattern...
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Keywords:
Economic Fluctuations;
Geographic Collocation;
Input-output Linkages;
Propagation;
Shocks;
Networks;
Fluctuation;
System Shocks;
Macroeconomics
Acemoglu, Daron, Ufuk Akcigit, and William Kerr. "Networks and the Macroeconomy: An Empirical Exploration." Harvard Business School Working Paper, No. 16-006, July 2015.